scholarly journals Global burden of chronic obstructive pulmonary disease attributable to ambient particulate matter pollution and household air pollution from solid fuels from 1990 to 2019

2022 ◽  
Author(s):  
Yinglin Wu ◽  
Shiyu Zhang ◽  
Bingting Zhuo ◽  
Miao Cai ◽  
Zhengmin Min Qian ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Air Pollution ◽  
Particulate Matter ◽  
Pulmonary Disease ◽  
Solid Fuels ◽  
Chronic Obstructive ◽  
Global Burden ◽  
Ambient Particulate Matter ◽  
Obstructive Pulmonary Disease ◽  
Particulate Matter Pollution

scholarly journals Investigation Regarding the Correlation between Particulate Matter 2.5 Air Pollution and Mortality Rates due to Chronic Obstructive Pulmonary Disease

2020 ◽  
Vol 6 (1) ◽  
pp. 53-59
Author(s):  
Ekta Dhanoa
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Air Pollution ◽  
Particulate Matter ◽  
Pulmonary Disease ◽  
Correlation Coefficient ◽  
Pearson Correlation ◽  
Chronic Obstructive ◽  
Pearson Correlation Coefficient ◽  
Obstructive Pulmonary Disease ◽  
The Relationship

In 2015, 3.2 million people died due to Chronic Obstructive Pulmonary Disease (COPD), worldwide. In fact, survival rates for those living with severe COPD are lower than for those with cancer. The one known contributor to this disease is air pollution, and with its rising levels every year, it is necessary to determine the exact correlation between air pollution and COPD. Data was gathered for a selection of 20 countries from the World Bank Database and Health Data Database. This data was graphed and analyzed using the Pearson correlation coefficient, which is a statistical test that measures the relationship between 2 variables. When calculated, the Pearson correlation coefficient was 0.756, determining that there is a significant relationship between air pollution and COPD. Through the investigation, it is concluded that there is a positive correlation between PM2.5 air pollution and mortality rate due to COPD. PM2.5 is a component of air pollution defined as the amount of atmospheric particulate matter with a diameter less than 2.5 micrometers. Due to its small physical nature, PM2.5 can easily infiltrate the lungs, causing infections in the respiratory organs. They can reach the bronchi and even the alveoli, causing inflammation which ultimately results in COPD and premature deaths. Therefore, this research will aim to investigate the relationship between PM2.5 air pollution and COPD, allowing for a better understanding of these variables.

scholarly journals Chronic Exposure to Ambient Particulate Matter Induces Gut Microbial Dysbiosis in a Rat COPD Model

2020 ◽  
Author(s):  
Naijian Li ◽  
Zhaowei Yang ◽  
Baoling Liao ◽  
Tianhui Pan ◽  
Jinding Pu ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Particulate Matter ◽  
Pulmonary Disease ◽  
Chronic Exposure ◽  
Short Chain Fatty Acids ◽  
Chronic Obstructive ◽  
Ambient Particulate Matter ◽  
Microbial Composition ◽  
Obstructive Pulmonary Disease ◽  
Microbial Dysbiosis

Abstract Background: The role of the gut microbiota in the pathogenesis of chronic obstructive pulmonary disease following exposure to ambient particulate matter is largely unknown. We hypothesized that exposure alters gut microbial composition and metabolites and may involved in the pathogenesis of chronic obstructive pulmonary disease.Methods: Fifty-four male Sprague-Dawley rats were exposed to clean air, biomass fuel, or motor vehicle exhaust for 4, 12, and 24 weeks. Lung tissue was assessed histologically and gut microbial composition was assessed by 16S rRNA pyrosequencing. Serum lipopolysaccharide levels were measured and short-chain fatty acids in colon contents were quantified. Results: After a 24-week exposure to particulate matter, rats exhibited pulmonary inflammation and pathological changes characteristic of chronic obstructive pulmonary disease. The gut microbiome was characterized by decreased microbial richness and diversity, distinct overall microbial composition, lower levels of short-chain fatty acids, and higher serum lipopolysaccharide. Conclusion: Chronic exposure to ambient particulate matter induces gut microbial dysbiosis and metabolite shifts in a rat model of chronic obstructive pulmonary disease.

scholarly journals Chronic Exposure to Ambient Particulate Matter Induces Gut Microbial Dysbiosis in a Rat COPD Model

2020 ◽  
Author(s):  
Naijian Li ◽  
Zhaowei Yang ◽  
Baoling Liao ◽  
Tianhui Pan ◽  
Jinding Pu ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Particulate Matter ◽  
Pulmonary Disease ◽  
Chronic Exposure ◽  
Short Chain Fatty Acids ◽  
Chronic Obstructive ◽  
Ambient Particulate Matter ◽  
Microbial Composition ◽  
Obstructive Pulmonary Disease ◽  
Microbial Dysbiosis

Abstract Background The role of the gut microbiota in the pathogenesis of chronic obstructive pulmonary disease following exposure to ambient particulate matter is largely unknown. We hypothesized that exposure alters gut microbial composition and metabolites and is involved in the pathogenesis of chronic obstructive pulmonary disease. Methods Fifty-four male Sprague-Dawley rats were exposed to clean air, biomass fuel, or motor vehicle exhaust for 4, 12, and 24 weeks. Lung tissue was assessed histologically and gut microbial composition was assessed by 16S rRNA pyrosequencing. Serum lipopolysaccharide levels were measured and short-chain fatty acids in colon contents were quantified. Results After a 24-week exposure to particulate matter, rats exhibited pulmonary inflammation and pathological changes characteristic of chronic obstructive pulmonary disease. The gut microbiome was characterized by decreased microbial richness and diversity, distinct overall microbial composition, lower levels of short-chain fatty acids, and higher serum lipopolysaccharide. Conclusion Chronic exposure to ambient particulate matter induces gut microbial dysbiosis and metabolite shifts in a rat model of chronic obstructive pulmonary disease.

scholarly journals Effects of Particulate Matter Education on Self-Care Knowledge Regarding Air Pollution, Symptom Changes, and Indoor Air Quality among Patients with Chronic Obstructive Pulmonary Disease

2020 ◽  
Vol 17 (11) ◽  
pp. 4103 ◽  
Author(s):  
Su-Er Guo ◽  
Miao-Ching Chi ◽  
Su-Lun Hwang ◽  
Chieh-Mo Lin ◽  
Yu-Ching Lin
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Air Pollution ◽  
Particulate Matter ◽  
Pulmonary Disease ◽  
Self Care ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Symptom Changes ◽  
Experimental Group

The burden of illness resulting from adverse environmental exposure is significant. Numerous studies have examined self-care behaviors among patients with chronic obstructive pulmonary disease (COPD), but seldom assess these behaviors in relation to air pollution. The study aims to examine the effects of particulate matter (PM) education on prevention and self-care knowledge regarding air pollution, symptom changes, and indoor PM concentration levels among patients with COPD. A longitudinal, quasi-experimental design using a generalized estimating equation examined the effectiveness of the education intervention. Participants were 63 patients with COPD, of whom only 25 received intervention. Levels of PM2.5 and PM10 decreased in the first-month follow-up in the experimental group. Improvement of knowledge and prevention regarding PM in the first and third months were also greater in the experimental group compared to the control. Regarding the COPD assessment test and physical domain scores, the experimental group exhibited a greater improvement in the first-month follow-up. Scores on the psychological domain significantly changed in the sixth-month follow-up. The PM education coordinated by nurses improved the health of participants, maintaining six-month effects. Further studies should evaluate the practice barriers and effects of health education on preventive self-care behaviors regarding indoor PM among patients with COPD.

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