Overview on the Current Status of Zika Virus Pathogenesis and Animal Related Research

2017 ◽  
Vol 12 (3) ◽  
pp. 371-388 ◽  
Author(s):  
Shashank S. Pawitwar ◽  
Supurna Dhar ◽  
Sneham Tiwari ◽  
Chet Raj Ojha ◽  
Jessica Lapierre ◽  
...  
Keyword(s):  
Zika Virus ◽  
Current Status ◽  
Related Research

scholarly journals Current Status of Zika Virus Vaccines: Successes and Challenges

Vaccines ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 266 ◽  
Author(s):  
Aryamav Pattnaik ◽  
Bikash R. Sahoo ◽  
Asit K. Pattnaik
Keyword(s):  
Zika Virus ◽  
Viral Infections ◽  
Current Status ◽  
Effective Vaccine ◽  
Congenital Diseases ◽  
Vaccine Candidates ◽  
Efficacy Trials ◽  
Nucleic Acid Vaccines ◽  
Funding Agencies ◽  
Inactivated Vaccines

The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) in adults. The unprecedented nature of the epidemic and serious diseases associated with the viral infections prompted the global research community to understand the immunopathogenic mechanisms of the virus and rapidly develop safe and efficacious vaccines. This has led to a number of ZIKV vaccine candidates that have shown significant promise in human clinical trials. These candidates include nucleic acid vaccines, inactivated vaccines, viral-vectored vaccines, and attenuated vaccines. Additionally, a number of vaccine candidates have been shown to protect animals in preclinical studies. However, as the epidemic has waned in the last three years, further development of the most promising vaccine candidates faces challenges in clinical efficacy trials, which is needed before a vaccine is brought to licensure. It is important that a coalition of government funding agencies and private sector companies is established to move forward with a safe and effective vaccine ready for deployment when the next ZIKV epidemic occurs.

Reflections on Research in Kinesiology

2021 ◽  
pp. 1-7
Author(s):  
Karl M. Newell
Keyword(s):  
Physical Activity ◽  
Research Agenda ◽  
Healthy Lifestyle ◽  
Human Movement ◽  
Current Status ◽  
Special Issue ◽  
New Developments ◽  
Related Research ◽  
Research And Teaching ◽  
Initial Research

This paper provides reflections on the progress to date and current status of research in kinesiology. The accompanying overview articles in this special issue of Kinesiology Review show that the contemporary disciplinary/professional foci of kinesiology remain, by and large, the same as the initial research and teaching structures of 50 years ago, as outlined in the inaugural overviews. Nevertheless, within this prevailing disciplinary/professional structure, there have been many new developments in movement-related research, including the juxtaposition of novel alignments and integrations of certain specializations of kinesiology. There is general consensus that the quality and quantity of research in kinesiology have advanced substantially, albeit unevenly, on multiple fronts, both within and between the areas of specialization. The research agenda in kinesiology has benefitted from the growing realization of the centrality of human movement and physical activity in contributing to a healthy lifestyle for individuals and societies.

Peer-to-Peer SIP for Mobile Computing

2011 ◽  
pp. 326-347 ◽  
Author(s):  
Erkki Harjula ◽  
Jani Hautakorpi ◽  
Nicklas Beijar ◽  
Mika Ylianttila
Keyword(s):  
Information Technology ◽  
Working Group ◽  
Task Force ◽  
Peer To Peer ◽  
Current Status ◽  
The Internet ◽  
Heterogeneous Environments ◽  
Information Technology Industry ◽  
Related Research ◽  
Technology Industry

Due to the increasing popularity of Peer-to-Peer (P2P) computing, the information technology industry and standardization organizations have started to direct their efforts on standardizing P2P algorithms and protocols. The Internet Engineering Task Force (IETF) has recently formed the Peer-to-Peer SIP (P2PSIP) working group for enabling serverless operation of Session Initiation Protocol (SIP). This chapter introduces the P2PSIP by presenting its background and purpose, operational principles, current status, and application areas. The focus is on the challenges and problem areas from the viewpoint of standardization and related research. The mobile- and heterogeneous environments are considered with special care. The authors provide a glance to the existing and emerging solutions that may be used in tackling the mentioned challenges and thus paving the way for successful deployment of P2PSIP in mobile environments.

scholarly journals Metallomics in environmental and health related research: Current status and perspectives

2012 ◽  
Vol 58 (2) ◽  
pp. 169-176 ◽  
Author(s):  
LiGang Hu ◽  
Bin He ◽  
YuChuan Wang ◽  
GuiBin Jiang ◽  
HongZhe Sun
Keyword(s):  
Current Status ◽  
Related Research ◽  
Health Related Research ◽  
Health Related

scholarly journals Development of vaccines against the sexually transmitted infections gonorrhoea, syphilis, Chlamydia, herpes simplex virus, human immunodeficiency virus and Zika virus

2020 ◽  
Vol 8 ◽  
pp. 251513552092388
Author(s):  
Edwin David G. McIntosh
Keyword(s):  
Human Immunodeficiency Virus ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Sexually Transmitted Infections ◽  
Zika Virus ◽  
Vaccine Development ◽  
Current Status ◽  
Sexually Transmitted ◽  
Immunodeficiency Virus ◽  
Simplex Virus

The success in preventing hepatitis B virus and human papillomavirus infections by means of vaccination paves the way for the development of other vaccines to prevent sexually transmitted infections (STIs) such as gonorrhoea, syphilis, chlamydia, herpes simplex virus, human immunodeficiency virus and Zika virus. The current status of vaccine development for these infections will be explored in this review. The general principles for success include the need for prevention of latency, persistence and repeat infections. A reduction in transmission of STIs would reduce the global burden of disease. Therapeutic activity of vaccines against STIs would be advantageous over preventative activity alone, and prevention of congenital and neonatal infections would be an added benefit. There would be an added value in the prevention of long-term consequences of STIs. It may be possible to re-purpose ‘old’ vaccines for new indications. One of the major challenges is the determination of the target populations for STI vaccination.

scholarly journals The current status of Zika virus in Southeast Asia

2016 ◽  
Vol 38 ◽  
pp. e2016026 ◽  
Author(s):  
Viroj Wiwanitkit
Keyword(s):  
Southeast Asia ◽  
Zika Virus ◽  
Current Status

Need for more research on and health interventions for transgender people

Sexual Health ◽  
2017 ◽  
Vol 14 (2) ◽  
pp. 196 ◽  
Author(s):  
Yeimer Ortiz-Martínez ◽  
Carlos Miguel Ríos-González
Keyword(s):  
Latin American ◽  
Low Income ◽  
Scientific Output ◽  
Scientific Production ◽  
Current Status ◽  
Transgender People ◽  
Related Research ◽  
Medline Search ◽  
Bisexual And Transgender ◽  
The Uk

Background Recently, lesbian, gay, bisexual, and transgender (LGBT) scientific production is growing, but transgender (TG) people is less considered in the LGBT-related research, highlighting the lack of representative data on this neglected population. Methods: To assess the current status of scientific production on TG population, a bibliometric study was performed using the articles on TG people deposited in five databases, including PubMed/Medline, Scopus, Science Citation Index (SCI), Scientific Electronic Library Online (SciELO) and Latin American and Caribbean Health Sciences Literature (LILACS). Results: The PubMed/Medline search retrieved 2370 documents, which represented 0.008% of all articles recorded in Medline. The Scopus search identified 4974 articles. At SCI, 2863 articles were identified. A search of the SciELO database identified 39 articles, whereas the LILACS search identified 44 articles. Most papers were from the US (57.59%), followed by Canada (5.15%), the UK (4.42%), Australia (3.19%), The Netherlands (2.46%) and Peru (1.83%). These six countries accounted for 74.6% of all scientific output. Conclusions: The findings indicate that the TG-related research is low, especially in low-income developing countries, where stigma and discrimination are common. More awareness, knowledge, and sensitivity in healthcare communities are needed to eliminate barriers in health attention and research in this population.

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