Risk of Second Primary Malignancies in Lung Cancer Survivors – The Influence of Different Treatments

2016 ◽  
Vol 12 (2) ◽  
pp. 219-227 ◽  
Author(s):  
Vincent Yi-Fong Su ◽  
Chia-Jen Liu ◽  
Yuh-Min Chen ◽  
Teh-Ying Chou ◽  
Tzeng-Ji Chen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Survivors ◽  
Second Primary ◽  
Second Primary Malignancies

scholarly journals Risk of second primary malignancies among cancer survivors in the United States, 1992 through 2008

Cancer ◽  
2016 ◽  
Vol 122 (19) ◽  
pp. 3075-3086 ◽  
Author(s):  
Nicholas Donin ◽  
Christopher Filson ◽  
Alexandra Drakaki ◽  
Hung-Jui Tan ◽  
Alex Castillo ◽  
...  
Keyword(s):  
United States ◽  
Cancer Survivors ◽  
The United States ◽  
Second Primary ◽  
Second Primary Malignancies

Second primary lung cancer in the United States: 1992–2008.

2017 ◽  
Vol 35 (6_suppl) ◽  
pp. 309-309
Author(s):  
Nicholas Donin ◽  
Lorna Kwan ◽  
Andrew T. Lenis ◽  
Drakaki Alexandra ◽  
Mark S. Litwin ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Bladder Cancer ◽  
Cancer Screening ◽  
Cancer Survivors ◽  
Lung Cancer Screening ◽  
The United States ◽  
Second Primary ◽  
Incidence And Mortality ◽  
Screening Trial

309 Background: Tobacco smoke is a known risk factor for both bladder and lung cancer. We hypothesized that bladder cancer survivors are at high risk for second primary lung cancers (SPLC), and sought to describe the incidence and mortality attributable to SPLC among survivors of bladder cancer as well as other common cancers in the United States. Methods: We identified adult patients diagnosed with a localized primary malignancy from 8 of the most common non-pulmonary cancer sites in Surveillance, Epidemiology, and End Results (SEER) data from 1992–2008. We explored factors associated with the incidence and mortality from SPLC using bivariable and multivariable models. Finally, we compared standardized incidence rates (SIRs) for SPLC in our cohort with the control arm of the National Lung Screening Trial (NLST), a large lung cancer screening trial in patients at high risk for lung cancer. Results: We identified 1,431,809 survivors of common non-pulmonary cancers, of whom 24,477 (1.7%) developed SPLC at a mean (SD) follow-up of 5.7 (3.6) years. Bladder cancer survivors developed SPLC at twice the rate of other cancer survivors, with 10% developing SPLC in the 20 years following their bladder cancer diagnosis. Increasing age and male gender were independent risk factors for SPLC, irrespective of the primary cancer type. Of patients who developed SPLC, 19,059 (78%) died during follow-up. Lung cancer was responsible for 73% of these deaths, such that over half (57%) of the cancer survivors who develop SPLC ultimately died of lung cancer. Bladder cancer survivors demonstrated a SIR of 512 cases/100,000 person-years, which approaches the rate (572 cases/100,000 person-years) seen in the control arm of the NLST. Conclusions: Over half of patients who develop SPLC died of their disease. Almost 10% of bladder cancer survivors develop SPLC in the 20-years following their diagnosis. This rate approaches that seen in the control arm of the NLST, suggesting that the incidence in bladder cancer survivors could justify lung cancer screening in this population. Further efforts to better define the potential risks and benefits of lung cancer screening in bladder cancer survivors is warranted.

Prognosis of lung cancer as a second primary malignancy among cancer survivors: A population-based cohort study.

2018 ◽  
Vol 36 (15_suppl) ◽  
pp. e21005-e21005
Author(s):  
Lei Deng ◽  
Zhengrui Xiao ◽  
Changchuan Jiang ◽  
Qian Wang ◽  
Haiying Cheng ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cohort Study ◽  
Cancer Survivors ◽  
Population Based ◽  
Second Primary ◽  
Second Primary Malignancy ◽  
Primary Malignancy

scholarly journals Association of EGFR mutations in second primary lung cancer and HER2 expression in breast cancer survivors

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Yoon Jung Jang ◽  
Seo Yun Kim ◽  
Hong Kyu Jung ◽  
Hye-Ryoun Kim ◽  
Cheol Hyeon Kim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lung Cancer ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Primary Lung Cancer ◽  
Egfr Mutations ◽  
Second Primary ◽  
Her2 Expression ◽  
Second Primary Lung Cancer

scholarly journals The Impact of Second Primary Malignancies on Head and Neck Cancer Survivors: A Nationwide Cohort Study

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e62116 ◽  
Author(s):  
Li-Jen Liao ◽  
Hsu-Wen Chou ◽  
Chi-Te Wang ◽  
Chen-Shuan Chung ◽  
Mei-Shu Lai
Keyword(s):  
Cohort Study ◽  
Head And Neck Cancer ◽  
Cancer Survivors ◽  
Head And Neck ◽  
Neck Cancer ◽  
Second Primary ◽  
Second Primary Malignancies ◽  
The Impact

Abstract 3287: Survival disparities for second primary malignancies diagnosed among childhood cancer survivors: A population-based assessment

2019 ◽  
Author(s):  
Austin L. Brown ◽  
Vidal M. Arroyo ◽  
Jennifer Agrusa ◽  
Michael E. Scheurer ◽  
Maria M. Gramatges ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Population Based ◽  
Second Primary ◽  
Second Primary Malignancies
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