The Impact of Second Primary Malignancies on Head and Neck Cancer Survivors: A Nationwide Cohort Study

With improvements in locoregional control, the problem of second primary malignancies is rapidly being pushed to the forefront of head and neck oncology. While the constant long-term risk for the head and neck cancer patient has been well established, efforts at prevention, early detection, and treatment have been somewhat futile. Recent advances in genetic predisposition, biomarkers, photodiagnostic imaging, and differentiation therapy may soon offer improved outcomes. The literature is reviewed and current research is presented regarding the history, epidemiology, etiology, diagnosis, and treatment of second primary malignancies.

Download Full-text

The impact of timing and modalities of dental prophylaxis on the risk of 5-fluorouracil–related oral mucositis in patients with head and neck cancer: a nationwide population-based cohort study

Supportive Care in Cancer ◽

10.1007/s00520-020-05825-y ◽

2020 ◽

Author(s):

Yi-Fang Huang ◽

Shih-Ping Liu ◽

Chih-Hsin Muo ◽

Hsuan-Ju Chen ◽

Yu-Fang Liao ◽

...

Keyword(s):

Cohort Study ◽

Head And Neck Cancer ◽

Head And Neck ◽

Neck Cancer ◽

Oral Mucositis ◽

Population Based ◽

Dental Prophylaxis ◽

The Impact

Download Full-text

Partner’s survivorship care needs: Multivariable analysis in head and neck cancer patients.

Journal of Clinical Oncology ◽

10.1200/jco.2016.34.3_suppl.120 ◽

2016 ◽

Vol 34 (3_suppl) ◽

pp. 120-120 ◽

Cited By ~ 1

Author(s):

Meredith Elana Giuliani ◽

Maurene McQuestion ◽

Lorna Sampson ◽

Lisa W Le ◽

Jennifer M. Jones ◽

...

Keyword(s):

Head And Neck Cancer ◽

Cancer Survivors ◽

Head And Neck ◽

Cancer Patients ◽

Neck Cancer ◽

Unmet Needs ◽

Multivariable Analysis ◽

Significant Proportion ◽

Unmet Need ◽

The Impact

120 Background: The purpose of this study was to determine the number and predictors of head and neck cancer (HNC) survivors’ partners unmet needs and how they correspond to the unmet needs of the survivor. Methods: This study accrued consenting partners from among 158 patients with HNC who had completed a onetime survey including demographic information and the Cancer Survivors’ Unmet Needs Measure (CaSUN) between January 2013 and May 2014. Patients’ caregivers were invited to complete the Cancer Survivors’ Partners Unmet Needs Survey (CaSPUN). The mean (± standard deviation) number and proportion of unmet needs on the CaSPUN was calculated. Multivariable analyses (MVA) were performed to determine factors associated with greater unmet needs using linear regression. Kappa co-efficient was calculated to examine the agreement between the unmet needs of patients and their partners on 22 corresponding items. Results: The CaSPUN survey was completed by 44 partners of head and neck cancer survivors. At least one unmet need was reported by 29 partners and 4 had a very high number of needs between 31 and 35. The most common unmet needs were “I need help to manage my concerns about the cancer coming back” (41%), “I need more accessible hospital parking” (34%), “ I need help to cope with others not acknowledging the impact of having a partner experience cancer has had on my own life” (30%), “ I need help dealing with changes that cancer has caused in my partner” (27%) and “I need to know all my partners doctors talk to each other to coordinate my partner’s care” (27%). Of the 5 most common items, 3 were in the Relationships domain. On MVA increasing number of unmet needs in patients was significantly associated with increased unmet needs in their partners (p < 0.01). Of the 22 paired items there was fair agreement in 12 items, moderate agreement in 8 items and good agreement in 2 items between patients and partners. Conclusions: A significant proportion of partners of cancer patients experience unmet needs which may differ from those of the patient themselves. Survivorship program should consider independent needs assessment and program development for partners.

Download Full-text