Entropy and distance maps-guided segmentation of articular cartilage: data from the Osteoarthritis Initiative

2022 ◽  
Author(s):  
Zezhong Li ◽  
Kangming Chen ◽  
Peng Liu ◽  
Xiaodong Chen ◽  
Guoyan Zheng
Keyword(s):  
Articular Cartilage ◽  
Osteoarthritis Initiative

scholarly journals Can Signal Abnormalities Detected with MR Imaging in Knee Articular Cartilage Be Used to Predict Development of Morphologic Cartilage Defects? 48-Month Data from the Osteoarthritis Initiative

Radiology ◽  
2016 ◽  
Vol 281 (1) ◽  
pp. 158-167 ◽  
Author(s):  
Benedikt J. Schwaiger ◽  
Alexandra S. Gersing ◽  
John Mbapte Wamba ◽  
Michael C. Nevitt ◽  
Charles E. McCulloch ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Mr Imaging ◽  
Cartilage Defects ◽  
Osteoarthritis Initiative

scholarly journals VITAMIN K ANTAGONISM AND CHONDROCALCINOSIS IN THE OSTEOARTHRITIS INITIATIVE

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S56-S56
Author(s):  
M Kyla Shea ◽  
Richard F Loeser ◽  
Timothy E McAlindon ◽  
Sarah L Booth
Keyword(s):  
Articular Cartilage ◽  
Vitamin K ◽  
Protein Function ◽  
Joint Pain ◽  
Prevalence Ratio ◽  
Dietary Vitamin ◽  
X Rays ◽  
Cross Sectional ◽  
Dependent Protein ◽  
Osteoarthritis Initiative

Abstract Calcification of articular cartilage, known as chondrocalcinosis, becomes more prevalent with age. Although chondrocalcinosis can be characteristic of osteoarthritis, it has been associated with more joint pain and disability independent of osteoarthritis severity. Identifying novel modifiable risk factors for chondrocalcinosis may help reduce joint pain and disability. One potential risk factor involves vitamin K because vitamin K-dependent proteins that inhibit calcification are present in articular cartilage. To test the hypothesis that vitamin K antagonism is associated with more chondrocalcinosis, we evaluated the cross-sectional association between warfarin use and chondrocalcinosis prevalence in the Osteoarthritis Initiative (n=1472, 60% female, mean age 64 years). Warfarin is a vitamin K antagonist that interferes with vitamin K-dependent protein function. In a secondary analysis we evaluated whether the prevalence of chondrocalcinosis differed according to dietary vitamin K intake. Chondrocalcinosis of the knee, evaluated using plain x-rays, was detected in 8% of participants. It was three times more prevalent in warfarin users (n=20) compared to non-users [prevalence ratio (95% confidence interval) (PR(95%CI)): 3.02(1.42-6.46); p=0.004, adjusted for age, sex, race, BMI]. Chondrocalcinosis prevalence did not differ according to vitamin K intake [PR(95%CI), compared to tertile 3 (≥189 mcg/d): tertile 1 (<96 mcg/d) =1.30(0.82-2.07), tertile 2 (96-189 mcg/d) =1.17(0.76-1.81), p-trend=0.623, adjusted for age, sex, race, BMI, energy intake]. That chondrocalcinosis prevalence differed according to warfarin use, but not vitamin K intake, suggests vitamin K-dependent protein function may be involved in chondrocalcinosis development. Since warfarin was not commonly used in this cohort, additional studies are needed to substantiate our findings.

scholarly journals Comparison of different material models of articular cartilage in 3D computational modeling of the knee: Data from the Osteoarthritis Initiative (OAI)

2016 ◽  
Vol 49 (16) ◽  
pp. 3891-3900 ◽  
Author(s):  
Olesya Klets ◽  
Mika E. Mononen ◽  
Petri Tanska ◽  
Miika T. Nieminen ◽  
Rami K. Korhonen ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Computational Modeling ◽  
Material Models ◽  
Osteoarthritis Initiative

scholarly journals Is Weight Loss Associated with Less Progression of Changes in Knee Articular Cartilage among Obese and Overweight Patients as Assessed with MR Imaging over 48 Months? Data from the Osteoarthritis Initiative

Radiology ◽  
2017 ◽  
Vol 284 (2) ◽  
pp. 508-520 ◽  
Author(s):  
Alexandra S. Gersing ◽  
Benedikt J. Schwaiger ◽  
Michael C. Nevitt ◽  
Gabby B. Joseph ◽  
Nattagan Chanchek ◽  
...  
Keyword(s):  
Weight Loss ◽  
Articular Cartilage ◽  
Mr Imaging ◽  
Osteoarthritis Initiative

scholarly journals 112 EARLY DETECTION OF CHANGES IN ARTICULAR CARTILAGE MORPHOLOGY: DATA FROM THE OSTEOARTHRITIS INITIATIVE

2010 ◽  
Vol 18 ◽  
pp. S57-S58 ◽  
Author(s):  
J.G. Tamez-Peña ◽  
P.C. González ◽  
E.H. Schreyer ◽  
J.M. Farber ◽  
S.M. Totterman
Keyword(s):  
Articular Cartilage ◽  
Early Detection ◽  
Osteoarthritis Initiative
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