Epidemiological Evaluation of Dupuytren's Disease Incidence and Prevalence Rates in Relation to Etiology

Dupuytren's Disease (DD) is a common, fibroproliferative disorder affecting the palmar surface of the hands which is often irreversible and progressive. Understanding the epidemiology of DD is important in order to provide clues to its etiopathogenesis. This review aims to evaluate the epidemiological studies carried out in DD since 1951. Studies evaluating the epidemiology of DD were searched using Medline, Pubmed, and Scopus which dated back from 1951 to current date. Inclusion criteria were any studies investigating the prevalence or incidence of DD in any population group. A total of 620 articles were cited. Forty-nine studies were subsequently identified as relevant to evaluating the epidemiology of DD. The prevalence of DD in all studies increased with age with a male to female ratio of approximately 5.9:1. Prevalence rates ranged from 0.2% to 56% in varying age, population groups, and methods of data collection. The highest prevalence rate was reported in a study group of epileptic patients. Although, only one study calculated the incidence (as opposed to prevalence) of DD to be equal to 34.3 per 100,000 men (0.03%). In conclusion, the prevalence of DD in different geographical locations is extremely variable, and it is not clear whether this is genetic, environmental, or a combination of both. The majority of the prevalence studies have been conducted in Scandinavia or the UK, and the vast changes in population structure, the changes in prevalence of associated diseases, and the change in diagnostic criteria of DD makes understanding the epidemiology of this condition difficult.

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The prevalence of early childhood autism: comparison of administrative and epidemiological studies

Psychological Medicine ◽

10.1017/s0033291700007522 ◽

1976 ◽

Vol 6 (1) ◽

pp. 89-100 ◽

Cited By ~ 95

Author(s):

Lorna Wing ◽

Sybil R. Yeates ◽

Lorna M. Brierley ◽

Judith Gould

Keyword(s):

Early Childhood ◽

Total Population ◽

Local Authority ◽

Epidemiological Studies ◽

Case Note ◽

Lower Prevalence ◽

Prevalence Rates ◽

Handicapped Children ◽

Prevalence Studies ◽

Wide Range

SynopsisThe results of surveys and inquiries to identify autistic children, carried out in England and Wales, the U.S.A. and Denmark, are compared. Three studies, in each of which either a total population of children or a wide range of handicapped children was screened, using case-note inspection and interviews, all estimated the prevalence of the autistic syndrome to be between four and five children per 10,000 aged under 15 years. Inquiries that counted diagnosed cases only or that relied upon local authority records produced much lower prevalence rates for the autistic syndrome. The reasons for this are examined, and the implications for prevalence studies of handicapping conditions are discussed.

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Epidemiology of Multiple Chronic Conditions: An International Perspective

Journal of Comorbidity ◽

10.15256/joc.2013.3.25 ◽

2013 ◽

Vol 3 (2) ◽

pp. 36-40 ◽

Cited By ~ 14

Author(s):

François G. Schellevis

Keyword(s):

Chronic Diseases ◽

Chronic Conditions ◽

Epidemiological Studies ◽

International Perspective ◽

Multiple Chronic Conditions ◽

Prevalence Rates ◽

Common Trends ◽

Strategic Framework ◽

Prevalence Studies ◽

The Usa

The epidemiology of multimorbidity, or multiple chronic conditions (MCCs), is one of the research priority areas of the U.S. Department of Health and Human Services (HHS) by its Strategic Framework on MCCs. A conceptual model addressing methodological issues leading to a valid measurement of the prevalence rates of MCCs has been developed and applied in descriptive epidemiological studies. Comparing these results with those from prevalence studies performed earlier and in other countries is hampered by methodological limitations. Therefore, this paper aims to put the size and patterns of MCCs in the USA, as established within the HHS Strategic Framework on MCCs, in perspective of the findings on the prevalence of MCCs in other countries. General common trends can be observed: increasing prevalence rates with increasing age, and multimorbidity being the rule rather than the exception at old age. Most frequent combinations of chronic diseases include the most frequently occurring single chronic diseases. New descriptive epidemiological studies will probably not provide new results; therefore, future descriptive studies should focus on the prevalence rates of MCCs in subpopulations, statistical clustering of chronic conditions, and the development of the prevalence rates of MCCs over time. The finding of common trends also indicates the necessary transition to a next phase of MCC research, addressing the quality of care of patients with MCCs from an organizational perspective and with respect to the content of care.

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Dorsal Dupuytren’s disease: a systematic review of published cases and treatment options

Journal of Hand Surgery (European Volume) ◽

10.1177/1753193419852171 ◽

2019 ◽

Vol 44 (9) ◽

pp. 963-971 ◽

Cited By ~ 2

Author(s):

Raphael Carloni ◽

Silvia Gandolfi ◽

Benedicte Elbaz ◽

Albane Bonmarchand ◽

Roberto Beccari ◽

...

Keyword(s):

Systematic Review ◽

Functional Result ◽

Treatment Options ◽

Proximal Interphalangeal Joint ◽

Dupuytren’S Disease ◽

Level Of Evidence ◽

Dupuytren's Disease ◽

Female Ratio ◽

Knuckle Pads ◽

Male To Female

Dorsal lesions in Dupuytren’s disease are rare and data concerning their epidemiology and management are sparse. We conducted a systematic review to summarize reported cases of dorsal Dupuytren’s disease. Pubmed, Cochrane, and Embase databases were searched from 1893 to 2018, and 17 articles were selected (525 patients). The male to female ratio was 3.8:1. The dorsal disease was bilateral in 225 patients (50%). The index was the most commonly affected finger (48 patients). The proximal interphalangeal joint was the most commonly affected (484 cases). The most frequently reported lesions were knuckle pads (503 patients), dorsal nodules between interphalangeal joints (14 patients), boutonnière deformities (12 patients), and swan-neck deformities (2 patients). Nearly half of the included patients were treated surgically. Postoperative functional result depended on the treated lesion. Most of the included studies had a low level of evidence. Higher-quality studies are necessary to confirm our findings.

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Two Significant Complications Following Percutaneous Needle Fasciotomy in a Patient on Anticoagulants

Journal of Hand Surgery (European Volume) ◽

10.1016/j.jhsb.2006.08.005 ◽

2006 ◽

Vol 31 (6) ◽

pp. 606-607 ◽

Cited By ~ 11

Author(s):

T. SYMES ◽

J. STOTHARD

Keyword(s):

False Aneurysm ◽

Clinical Excellence ◽

Dupuytren’S Disease ◽

Coagulation Cascade ◽

Flexor Digitorum Profundus ◽

Medical Problems ◽

Dupuytren's Disease ◽

The Uk ◽

Flexor Digitorum ◽

First Time

Percutaneous needle fasciotomy treatment of Dupuytren’s disease has been used on the continent for over two decades but has only recently gained popularity in the UK. The National Institute for Clinical Excellence published guidance in February 2004 stating that the procedure is safe and effective. We report a case of two complications in the same patient following the use of the technique, on only one occasion, in a patient who was anticoagulated. We believe that it is the first time that a false aneurysm has been reported following the procedure and that this was probably related to the inhibited coagulation cascade. The patient also sustained an injury to flexor digitorum profundus but had an intact superficialis tendon and we find it difficult to explain this occurrence. We report the above complication as we feel this technique may be chosen specifically in patients with co-existing medical problems such as anticoagulation.

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What patients want from the treatment of Dupuytren’s disease — is the Unité Rhumatologique des Affections de la Main (URAM) scale relevant?

Journal of Hand Surgery (European Volume) ◽

10.1177/1753193414524689 ◽

2014 ◽

Vol 40 (2) ◽

pp. 150-154 ◽

Cited By ~ 25

Author(s):

J. N. Rodrigues ◽

W. Zhang ◽

B. E. Scammell ◽

T. R. C. Davis

Keyword(s):

Face Validity ◽

Dupuytren’S Disease ◽

Level Of Evidence ◽

Term Outcome ◽

Dupuytren's Disease ◽

Long Term Outcome ◽

Specific Outcome ◽

Disease Specific Outcome Measure ◽

The Uk

Patients awaiting surgery for Dupuytren’s contractures listed the problems from their Dupuytren’s disease that had led them to request surgery and their relative priorities of the results of surgery. The listed problems were compared with the nine items comprising the Unité Rhumatologique des Affections de la Main (URAM) Dupuytren’s disease-specific outcome measure. One hundred and ten patients reported 278 problems. Ninety-four different combinations of problems were provided by patients, and over half (55%) of the problems were not captured by items in the URAM scale. The long-term outcome from surgery was relatively more important to patients than speed of recovery. The URAM tool may not be relevant to patients in the UK, and further assessment of its face validity is required before it is used. Level of evidence: III

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