Prevalence of Peripheral Polyneuropathy Before and After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy

The aim of this study was to explore the impact of bariatric surgery on fat and sweet taste perceptions and to determine the possible correlations with gut appetite-regulating peptides and subjective food sensations. Women suffering from severe obesity (BMI > 35 kg/m2) were studied 2 weeks before and 6 months after a vertical sleeve gastrectomy (VSG, n = 32) or a Roux-en-Y gastric bypass (RYGB, n = 12). Linoleic acid (LA) and sucrose perception thresholds were determined using the three-alternative forced-choice procedure, gut hormones were assayed before and after a test meal and subjective changes in oral food sensations were self-reported using a standardized questionnaire. Despite a global positive effect of both surgeries on the reported gustatory sensations, a change in the taste sensitivity was only found after RYGB for LA. However, the fat and sweet taste perceptions were not homogenous between patients who underwent the same surgery procedure, suggesting the existence of two subgroups: patients with and without taste improvement. These gustatory changes were not correlated to the surgery-mediated modifications of the main gut appetite-regulating hormones. Collectively these data highlight the complexity of relationships between bariatric surgery and taste sensitivity and suggest that VSG and RYGB might impact the fatty taste perception differently.

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Gut microbiota characterisation in obese patients before and after bariatric surgery

Beneficial Microbes ◽

10.3920/bm2017.0152 ◽

2018 ◽

Vol 9 (3) ◽

pp. 367-373 ◽

Cited By ~ 15

Author(s):

G. Campisciano ◽

S. Palmisano ◽

C. Cason ◽

M. Giuricin ◽

M. Silvestri ◽

...

Keyword(s):

Bariatric Surgery ◽

Weight Loss ◽

Gastric Bypass ◽

Sleeve Gastrectomy ◽

Gut Microbiota ◽

Good Health ◽

Normal Weight ◽

Obese Patients ◽

Before And After

Intestinal microbiota analysis of obese patients after bariatric surgery showed that Proteobacteria decreased after laparoscopic sleeve gastrectomy (SG), while it increased after laparoscopic gastric bypass (LGB). Comparing to normal weight (NW) patients, obese patients that were selected for SG showed an almost equal amount of Firmicutes and Bacteroidetes and the ratio was not affected by the surgery. Obese patients before LGB showed a predominance of Bacteroidetes, whose amount regained a relative abundance similar to NW patients after surgery. Obese patients before LGB showed the predominance of Bacteroides, which decreased after surgery in favour of Prevotella, a bacterium associated with a healthy diet. The bacteria detected at the highest percentages belonged to biofilm forming species. In conclusion, in this study, we found that the characterization of the gut microbial communities and the modality of mucosal colonisation have a central role as markers for the clinical management of obesity and promote the maintenance of good health and the weight loss.

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Wirkmechanismen der bariatrischen und metabolen Chirurgie

Therapeutische Umschau ◽

10.1024/0040-5930/a001072 ◽

2019 ◽

Vol 76 (3) ◽

pp. 123-127

Author(s):

Hanna Hosa ◽

Marco Bueter

Keyword(s):

Gastric Bypass ◽

Sleeve Gastrectomy

Zusammenfassung. Zusammenfassung: Bei steigender Prävalenz der Adipositas und der damit assoziierten Komorbiditäten rückt die bariatrische und metabole Chirurgie immer mehr in den Vordergrund, wobei weltweit der Roux-Y-Magenbypass (= Roux-en-Y Gastric- Bypass, RYGB) und der Schlauchmagen (= Sleeve gastrectomy, SG) die häufigsten Eingriffe darstellen. Der erzielte Gewichtsverlust und das veränderte Essverhalten scheinen dabei nicht wie initial vermutet ausschliesslich auf einer mechanischen Restriktion der Nahrungspassage und / oder einer kalorischen Malabsorption der aufgenommenen Nahrung zu beruhen, sondern vielmehr auf ein komplexes Zusammenspiel verschiedenster physiologischer Wirkmechanismen zurückführbar zu sein. Ziel des vorliegenden Artikels ist es deshalb, vor dem Hintergrund des aktuellen Wissenstandes einen kurzen Überblick über die wichtigsten Wirkmechanismen der bariatrischen und metabolen Chirurgie zu liefern.

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