Cardiorespiratory function and VO2 kinetics after sleeve gastrectomy: a follow-up analysis

Bariatric surgeries may lead to an improvement in metabolic fatty liver disease, and a reduction in the levels of the hepatic enzyme Alanine Aminotransferase (ALT). We compared the effects of Sleeve Gastrectomy (SG), Roux en Y Gastric Bypass (RYGB) and One Anastomosis Gastric Bypass (OAGB) on the levels of ALT by analysis of two-year follow-up data from 4980 patients in the Israeli Bariatric Registry that included laboratory tests and demographic information. Pre-operative characteristics of patients, and particularly levels of liver enzymes, were similar across surgery types. Regression modeling and retrospective matching showed that SG was superior to RYGB and OAGB in reducing ALT levels, and in reducing the fraction of patients with abnormally high ALT levels. Two-year post-surgery, an increase in ALT levels from normal to abnormal levels was observed in 5% of SG patients, and in 18% and 23% of RYGB and OAGB patients. In conclusion, SG leads to a greater reduction in ALT levels compared with bypass surgeries and a lower incidence of post-surgical elevation of ALT levels. Further studies are required to identify the cause for the rise in liver enzymes, and to determine whether ALT levels correlate with liver pathology especially following bariatric surgery.

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Laparoscopic sleeve gastrectomy for morbid obesity and Klinefelter syndrome: clinical report on two patients, with long-term follow-up

Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity ◽

10.1007/s40519-020-00951-2 ◽

2020 ◽

Cited By ~ 2

Author(s):

Emanuela Bianciardi ◽

Paolo Orsaria ◽

Cinzia Niolu ◽

Alberto Siracusano ◽

Paolo Gentileschi

Keyword(s):

Morbid Obesity ◽

Sleeve Gastrectomy ◽

Laparoscopic Sleeve Gastrectomy ◽

Klinefelter Syndrome ◽

Clinical Report ◽

Long Term Follow Up

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Diverted sleeve gastrectomy with ileal transposition in overweight, obese, and morbidly obese patients with type 2 diabetes: results of 1-year follow-up

Surgery for Obesity and Related Diseases ◽

10.1016/j.soard.2015.09.027 ◽

2016 ◽

Vol 12 (3) ◽

pp. 541-549 ◽

Cited By ~ 5

Author(s):

Alper Celik ◽

Eylem Cagiltay ◽

Surendra Ugale ◽

Muharrem Asci ◽

Bahri Onur Celik ◽

...

Keyword(s):

Type 2 Diabetes ◽

Sleeve Gastrectomy ◽

Morbidly Obese ◽

Obese Patients ◽

Ileal Transposition

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Short-Term Results of Single-Anastomosis Gastric Bypass After Failed Sleeve Gastrectomy

QJM ◽

10.1093/qjmed/hcab097.039 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Alaa Abbas Sabry ◽

Karim Sabry Abd-Elsamee ◽

Mohamed Ibrahim Mohamed ◽

Mohammed Mohamed Ahmed Abd-Elsalam

Keyword(s):

Weight Loss ◽

Gastric Bypass ◽

Sleeve Gastrectomy ◽

Weight Regain ◽

Revisional Surgery ◽

One Anastomosis Gastric Bypass ◽

Short Term ◽

Multicenter Studies ◽

Metabolic Outcomes

Abstract Background It is already known that Laparoscopic sleeve gastrectomy (LSG) has gained popularity as a stand-alone procedure with good short-term results for weight loss. However, in the long-term, weight regain is considered as a complication. Demand for secondary surgery is rising, partly for this reason, but through that study we try to discover the efficacy of conversion of failed sleeve gastrectomy to one anastomosis gastric bypass (OAGB) regarding weight loss and metabolic outcomes. Objective To asses the efficacy and safety of one anastomosis gastric bypass (OAGB) as a conversion surgery post Sleeve Gastrectomy failure as regard weight loss and metabolic outcomes. Patients and Methods This study is a retrospective cohort study which included 20 patients underwent one anastomosis gastric bypass at Ain-Shams University El-Demerdash Hospital, Cairo, Egypt and specialized bariatric center, Cairo, Egypt From February 2019 to July 2019 with 6 months of postoperative follow up till January 2019. Results In this study, we reviewed and analyzed the outcomes from the revision of the SG due to either inadequate weight loss or weight regain to one anastomosis gastric bypass (OAGB) with %EBWL of 6.65% at 1 month, 13.61 % at 3 months and 20.86% at 6 months. Conclusion OAGB appears to be an effective and safe therapeutic technique as a revisional surgery for failed primary SG with good short-term results for treating morbid obesity and its associated comorbidities with a significantly low rate of complications. However the EBWL was less than what is reported after primary OAGB weight. Multicenter studies with larger series of patients and longer term follow up after SG revisions to OAGB are warranted.

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EP.WE.1048Weight Regain After Sleeve Gastrectomy More Common in Male and Less Common in Super-Obese Patients - Results of an 18-Month Follow-up Study

British Journal of Surgery ◽

10.1093/bjs/znab308.111 ◽

2021 ◽

Vol 108 (Supplement_7) ◽

Author(s):

Ahmed Salman Bodla ◽

Jenny Abraham ◽

Neha Shah ◽

Vinod Menon

Keyword(s):

Sleeve Gastrectomy ◽

Revisional Surgery ◽

Patient Specific ◽

Obese Patients ◽

Inclusion Criteria ◽

Super Obese ◽

Burn Out ◽

Single Centre Study ◽

Male Patients

Abstract Aims Long-term success of Sleeve Gastrectomy (SG) is undermined by weight regain (WR). Several procedure- and patient-specific factors have been proposed in previous studies. Here we look at 18-month follow-up post-SG to investigate WR and patient-specific variables influencing this. Methods A single-centre study involving retrospective analysis of a prospectively-maintained database. Inclusion criteria: Primary non-revisional SG patients with adequate follow-up data to assess WL/WR trends. Patients were divided into two subgroups based on their %EWL between 6-to-12 and 12-to-18 months: weight regainers (WR) and weight losers/maintainers (WL/M). Results Out of 338 SG cases between 2012-2017, 180 met inclusion criteria of which 18.3% were men and 45% were super-obese. All patients lost weight during first 6 months (mean %EWL 52.3%, P < 0.0001). Between 6-to-12 months, 87.6% patients continued WL with a further mean %EWL of 10.35% (P < 0.0001). Between 12-to-18 months, a drastic deceleration/reversal of WL progress was observed with an average of only 0.76% EWL (P = 0.84), with 42% of patients regaining weight in this period (mean EWG 6.8%). Male patients encountered significantly higher WR rate (OR 3.27, P = 0.003), whereas it was much less frequent in pre-operatively super-obese patients (OR 0.48, P = 0.036). Moreover, there was no difference in the 6-month %EWL between WR and WL/M subgroups (P = 0.62), thus negating the possibility of WL burn-out phenomenon. Conclusions Different rates of WR in men and super-obese patients may indicate underlying behavioural and biological differences. More research is needed to investigate them in detail, having implications for revisional surgery and follow-up support.

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A 5-Year Follow-Up Study of Laparoscopic Sleeve Gastrectomy Among Morbidly Obese Adolescents: Does It Improve Body Image and Prevent and Treat Diabetes?

Obesity Surgery ◽

10.1007/s11695-017-2884-2 ◽

2017 ◽

Vol 28 (2) ◽

pp. 513-519 ◽

Cited By ~ 14

Author(s):

Moamena Ahmed El-Matbouly ◽

Nesreen Khidir ◽

Hussien Aly Touny ◽

Walid El Ansari ◽

Mohammed Al-Kuwari ◽

...

Keyword(s):

Body Image ◽

Sleeve Gastrectomy ◽

Laparoscopic Sleeve Gastrectomy ◽

Morbidly Obese ◽

Obese Adolescents ◽

Follow Up Study

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Six month-follow up of laparoscopic sleeve gastrectomy

Advanced Biomedical Research ◽

10.4103/2277-9175.178786 ◽

2016 ◽

Vol 5 (1) ◽

pp. 49 ◽

Cited By ~ 1

Author(s):

AminGhanei Anaraki ◽

Behrouz Keleidari ◽

Mohsen Mahmoudie ◽

MasoudSayadi Shahraki ◽

SamiraDvashi Jamalouee ◽

...

Keyword(s):

Sleeve Gastrectomy ◽

Laparoscopic Sleeve Gastrectomy

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A Very Rare Cause of Dilated Cardiomyopathy after Bariatric Surgery: Selenium Deficiency

Surgical Case Reports ◽

10.31487/j.scr.2021.08.20 ◽

2021 ◽

pp. 1-3

Author(s):

Gulay Kocak ◽

Munevver Gul Avsar ◽

Cansu Yazar ◽

Aylia Yesilova ◽

Gulcagri Yildiz ◽

...

Keyword(s):

Bariatric Surgery ◽

Trace Elements ◽

Sleeve Gastrectomy ◽

Dilated Cardiomyopathy ◽

Selenium Deficiency ◽

Water Soluble ◽

Nutritional Deficiencies ◽

Reduced Ejection Fraction ◽

Long Term Follow Up

Background: Sleeve gastrectomy for weight loss has increased significantly nowadays. Various complications may develop after this surgery that requires long-term follow-up of these patients. Nutrition is the most important aspect of the follow-up. The deficiency of trace elements, fat-soluble and water-soluble vitamins following bariatric surgeries have been well-described complications. Although nutritional supplementations are often initiated after bariatric surgery, the clinical outcomes related to the deficiency of trace elements have not been well known yet. Case Presentation: A 27-year-old woman who underwent a laparoscopic sleeve gastrectomy for surgical treatment of obesity 9 months ago presented to the emergency department with a signs of heart failure. Transthoracic echocardiography revealed dilated, poorly functioning left ventricle with reduced ejection fraction (28.9%) consistent with dilated cardiomyopathy. We assumed nutritional deficiencies secondary to sleeve gastrectomy as a cause of dilated cardiomyopathy, as the patient had inappropriate nutritional supplements after surgery. Laboratory tests revealed selenium and zinc deficiency that supported our hypothesis. Our patient completely recovered with adequate supplementation of selenium, zinc and thiamine. Conclusion: We highlighted that the early diagnosis of dilated cardiomyopathy due to selenium deficiency following bariatric surgery is of great importance since selenium deficiency is a cause of reversible cardiomyopathy.

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