Antioxidant Potential of Ulexite in Zebrafish Brain: Assessment of Oxidative DNA Damage, Apoptosis, and Response of Antioxidant Defense System

2020 ◽  
Author(s):  
Gonca Alak ◽  
Arzu Ucar ◽  
Veysel Parlak ◽  
Aslı Çilingir Yeltekin ◽  
Fatma Betül Özgeriş ◽  
...  
Keyword(s):  
Dna Damage ◽  
Oxidative Dna Damage ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Antioxidant Potential ◽  
Defense System ◽  
Zebrafish Brain

Increased oxidative DNA damage and impaired antioxidant defense system in patients with gastrointestinal cancer

2012 ◽  
Vol 23 (4) ◽  
pp. 350-354 ◽  
Author(s):  
Aymelek Gönenç ◽  
Aysun Hacışevki ◽  
Sabahattin Aslan ◽  
Meral Torun ◽  
Bolkan Şimşek
Keyword(s):  
Dna Damage ◽  
Gastrointestinal Cancer ◽  
Oxidative Dna Damage ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System

A Case-Control Study of Involvement of Oxidative DNA Damage and Alteration of Antioxidant Defense System in Patients with Basal Cell Carcinoma: Effect of Tumor Removal

2015 ◽  
Vol 87 ◽  
pp. S70
Author(s):  
Uraiwan Panich ◽  
Lapatsanant Chaisiriwong Chaisiriwong ◽  
Rungsima Wanitphakdeedecha ◽  
Panitta Sitthinamsuwan ◽  
Somruedee Chatsiricharoenkul ◽  
...  
Keyword(s):  
Dna Damage ◽  
Basal Cell Carcinoma ◽  
Oxidative Dna Damage ◽  
Antioxidant Defense ◽  
Case Control Study ◽  
Antioxidant Defense System ◽  
Case Control ◽  
Defense System ◽  
Tumor Removal ◽  
Control Study

scholarly journals Antioxidant Potential, Phytochemicals Composition, and Metal Contents of Datura alba

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Waliullah Khan ◽  
Sidra Subhan ◽  
Dilawar Farhan Shams ◽  
Sahib Gul Afridi ◽  
Riaz Ullah ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Defense ◽  
Radical Scavenging ◽  
Pharmaceutical Formulations ◽  
Antioxidant Defense System ◽  
Antioxidant Potential ◽  
Defense System ◽  
Metal Contents ◽  
Stem Extract ◽  
Free Radical Scavenging Assay

This study investigated the phytochemical characteristics and antioxidant activity in leaves, roots, stem, flower, and seed parts of Datura alba (D. alba). The study also assessed the heavy metal (Cr, Mn, Zn, and Cu) accumulation in each part of the plant. Among the phytochemicals, alkaloids were found only in leaves while tannins, flavonoids, and phenols were present in all parts of the plant. For antioxidant activity, free radical scavenging assay for 2,2-diphenyl-1-picrylhydrazyl (DPPH) was performed using ascorbic acid as the standard. Higher activity was shown by stem extract in methanol and leaf extract in n-hexane, ethyl acetate, and chloroform. Furthermore, all the target heavy metals were detected in all plant sections with the highest concentration of Zn in leaves and Cu in stem, root, flower, and seed. Due to stronger antioxidant potential and phytochemical composition, D. alba could prove as valuable prospect in pharmaceutical formulations by taking part in the antioxidant defense system against generation of free radicals.

scholarly journals Antioxidant defense system responses, lysosomal membrane stability and DNA damage in earthworms (Eisenia fetida) exposed to perfluorooctanoic acid: an integrated biomarker approach to evaluating toxicity

RSC Advances ◽  
2021 ◽  
Vol 11 (43) ◽  
pp. 26481-26492
Author(s):  
Zhifeng Wang ◽  
Chaona Li ◽  
Yuanyuan Shao ◽  
Weina Xue ◽  
Ning Wang ◽  
...  
Keyword(s):  
Dna Damage ◽  
Eisenia Fetida ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Lysosomal Membrane ◽  
Defense System ◽  
Integrated Biomarker Response ◽  
Toxicological Effects ◽  
Biomarker Response ◽  
Lysosomal Membrane Stability

The integrated biomarker response (IBR) index was calculated to evaluate the integrated toxicological effects of PFOA on earthworm Eisenia fetida.

Toxicological effects of pyraclostrobin on the antioxidant defense system and DNA damage in earthworms (Eisenia fetida)

2019 ◽  
Vol 101 ◽  
pp. 111-116 ◽  
Author(s):  
Junchao Ma ◽  
Chao Cheng ◽  
Zhongkun Du ◽  
Bing Li ◽  
Jinhua Wang ◽  
...  
Keyword(s):  
Dna Damage ◽  
Eisenia Fetida ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System ◽  
Toxicological Effects
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