Higher risk of chronic kidney disease and progressive kidney function impairment in primary aldosteronism than in essential hypertension. Case-control study

Endocrine ◽  
2021 ◽  
Author(s):  
María Fernández-Argüeso ◽  
Eider Pascual-Corrales ◽  
Nuria Bengoa Rojano ◽  
Ana García Cano ◽  
Lucía Jiménez Mendiguchía ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Essential Hypertension ◽  
Kidney Disease ◽  
Kidney Function ◽  
Primary Aldosteronism ◽  
Case Control Study ◽  
Case Control ◽  
Function Impairment ◽  
Control Study

scholarly journals Higher risk of chronic kidney disease and progressive kidney function impairment in primary aldosteronism than in essential hypertension. Case-control study

2021 ◽  
Author(s):  
María Fernández Argüeso ◽  
Eider Pascual-Corrales ◽  
Nuria Bengoa Rojano ◽  
Ana García Cano ◽  
Lucía Jiménez Mendiguchía ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Essential Hypertension ◽  
Kidney Function ◽  
Case Control Study ◽  
Case Control ◽  
Function Impairment ◽  
Degree Of Control ◽  
Control Study

Abstract Purpose: To study the differences in the prevalence, risk, and grade of control of different cardiometabolic comorbidities in patients with primary aldosteronism (PA) and essential hypertension (EH) matched by age, sex, and blood pressure levels at diagnosis.Methods: Case-control study of a secondary base (PA patients in follow-up in a tertiary hospital between 2018-20). Controls were patients with EH, matched by age, sex, and baseline diastolic (DBP) and systolic blood pressure (SBP). Results: Fifty patients with PA and 50 controls were enrolled in the study. At diagnosis, PA patients had a higher prevalence of chronic kidney disease (CKD) than controls (18.4% vs. 2.1%, P=0.008). No differences were detected in the prevalence of other cardiometabolic comorbidities nor in their degree of control (P>0.05). All patients received antihypertensive medical treatment and 10 PA patients underwent unilateral laparoscopic adrenalectomy.After a median follow-up of 31.9 [IQR=1.0-254.8] months, PA patients presented a greater degree of declination of kidney function than controls (Average decrease in glomerular filtration rate (MDRD-4) -17.6±3.1 vs -2.8±1.8 ml/min/1.73m2, P<0.001). There were no differences in the grade of SBP (P=0.840) and DBP control (P=0.191), nor in the risk of developing other comorbidities or in their degree of control.Conclusions: PA patients have a prevalence of CKD ten times higher than those with EH matched by age, sex, and blood pressure levels. Furthermore, the risk of kidney function impairment throughout the follow-up is significantly greater in PA patients and is independent of the degree of blood pressure control.

scholarly journals Acute kidney injury in 3182 patients admitted with COVID-19: a single center retrospective case-control study

2021 ◽  
Author(s):  
Fabio L Procaccini ◽  
Roberto Alcázar Arroyo ◽  
Marta Albalate Ramón ◽  
Esther Torres Aguilera ◽  
Juan Martín Navarro ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Kidney Disease ◽  
Respiratory Distress ◽  
Kidney Function ◽  
Case Control Study ◽  
Kidney Injury ◽  
Case Control ◽  
Retrospective Case ◽  
Control Study

Abstract Background Acute kidney injury (AKI) may develop in COVID-19 patients and may be associated with a worse outcome. The aim of this study is to describe AKI incidence during the first 45 days of the SARS-CoV2 pandemic in Spain, its reversibility and the association with mortality. Methods Observational retrospective case-control study based on patients hospitalized between March 1 and April 15, 2020 with SARS-CoV2 infection and AKI. Confirmed AKI cases were compared with stable kidney function patients for baseline characteristics, analytical data, treatment and renal outcome. Patients with end-stage kidney disease were excluded. Results AKI incidence was 17.22% among 3182 admitted COVID-19 patients and acute kidney disease (AKD) incidence was 6.82%. The most frequent causes of AKI were prerenal (68.8%) and sepsis (21.9%). Odds ratio for AKI was increased in patients with pre-existent hypertension (OR 2.58, 95% CI 1.71-3.89) and chronic kidney disease (OR 2.14, 95% CI 1.33-3.42) and in those with respiratory distress (OR 2.37, 95% CI 1.52-3.70). Low arterial pressure at admission increased the risk for stage 3 AKI (OR 1.65, 95% CI 1.09-2.50). Baseline kidney function was not recovered in 45.73% of overall AKI cases and in 52.75% of AKI patients with prior chronic kidney disease. Mortality was 38.5% compared to 13.4% of the overall sample population. AKI increased mortality risk at any time of hospitalization (HR 1.45, 95% CI 1.09-1.93). Conclusions AKI is frequent in COVID-19 patients and is associated to mortality, independently from acute respiratory distress syndrome. AKD was also frequent and merits adequate follow-up.

scholarly journals Association of Individual Non-Steroidal Anti-Inflammatory Drugs and Chronic Kidney Disease: A Population-Based Case Control Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0122899 ◽  
Author(s):  
Ylenia Ingrasciotta ◽  
Janet Sultana ◽  
Francesco Giorgianni ◽  
Andrea Fontana ◽  
Antonio Santangelo ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Control Study

A case-control study of the effects of nephrolithiasis in cats with chronic kidney disease

2007 ◽  
Vol 230 (12) ◽  
pp. 1854-1859 ◽  
Author(s):  
Sheri J. Ross ◽  
Carl A. Osborne ◽  
Chalermpol Lekcharoensuk ◽  
Lori A. Koehler ◽  
David J. Polzin
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Risk Factors for Herpes Zoster Infection in Patients With Chronic Kidney Disease: A Case-control Study

2021 ◽  
Author(s):  
Qiao Wang ◽  
Jiahui Ma ◽  
Zhenxing Li ◽  
Zhi Li ◽  
Dong Huang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Herpes Zoster ◽  
Kidney Disease ◽  
Odds Ratio ◽  
Case Control Study ◽  
Immunosuppressive Agents ◽  
Tertiary Hospital ◽  
Case Control ◽  
Control Study

Abstract Background: Chronic kidney disease (CKD) increases the susceptibility to the infection of herpes zoster (HZ). Less is known about the risk factors of HZ in CKD patients.Methods and Participants: This is a case-control study. CKD patients diagnosed with HZ infection between January 2015 and October 2020 in a tertiary hospital were identified. One age- and gender- matched control was paired for each case, matched to the date of initial HZ diagnose. The uni- and multivariate analysis were used to evaluate the risk factors for development of HZ in CKD patients.Results: Forty-six HZ patients and controls were identified. In general, about 80% (72 out of 92) patients were classified at end-stage renal disease (ESRD, CKD Ⅳ to Ⅴ). Multivariate analyses revealed that immunosuppressive agents (odds ratio: 12.50, 95% CI: 1.53-102.26, P=0.021) and dialysis (odds ratio: 3.33, 95% CI: 1.13-9.78, P=0.029) were independent risk factors of HZ in patient with CKD. Conclusion: Immunosuppressive medication and dialysis were associated with HZ infection in CKD. Further guideline may highlight the necessity of zoster vaccine for patients with CKD, who undertake immunosuppressive or dialysis treatment.

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