Role of miRNAs in diabetic neuropathy: mechanisms and possible interventions

The Role of Diabetes Mellitus in Diseases of the Gallbladder and Biliary Tract

Current Diabetes Reviews ◽

10.2174/1573399816666200305094727 ◽

2020 ◽

Vol 16 (9) ◽

pp. 931-948

Author(s):

Benjamin Rahmani ◽

Jason Gandhi ◽

Gunjan Joshi ◽

Noel L. Smith ◽

Inefta Reid ◽

...

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Diabetic Neuropathy ◽

Gallbladder Cancer ◽

Biliary Tract ◽

Treatment Approach ◽

Database Search ◽

Heavy Burden ◽

Prevalence Of Diabetes Mellitus

Background: The increasing prevalence of diabetes mellitus worldwide continues to pose a heavy burden. Though its gastrointestinal impact is appropriately recognized, the lesser known associations may be overlooked. Objective: We aim to review the negative implications of diabetes on the gallbladder and the biliary tract. Methods: A MEDLINE® database search of literature was conducted with emphasis on the previous five years, combining keywords such as "diabetes," "gallbladder," and "biliary". Results: The association of diabetes to the formation of gallstones, gallbladder cancer, and cancer of the biliary tract are discussed along with diagnosis and treatment. Conclusion: Though we uncover the role of diabetic neuropathy in gallbladder and biliary complications, the specific individual diabetic risk factors behind these developments is unclear. Also, in addition to diabetes control and surgical gallbladder management, the treatment approach also requires further focus.

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Exploring the molecular role of endostatin in diabetic neuropathy

Molecular Biology Reports ◽

10.1007/s11033-021-06205-3 ◽

2021 ◽

Vol 48 (2) ◽

pp. 1819-1836

Author(s):

Tuhin Mukherjee ◽

Tapan Behl ◽

Aayush Sehgal ◽

Saurabh Bhatia ◽

Harmanpreet Singh ◽

...

Keyword(s):

Diabetic Neuropathy

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The role of anticonvulsants, antidepressants and phenothiazines in the management of painful diabetic neuropathy

Practical Diabetes International ◽

10.1002/pdi.1960040410 ◽

1987 ◽

Vol 4 (4) ◽

pp. 174-178 ◽

Cited By ~ 1

Author(s):

Judith Cantrill

Keyword(s):

Diabetic Neuropathy ◽

Painful Diabetic Neuropathy

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PROTECTIVE ROLE OF FICUS RACEMOSA IN DIABETES INDUCED NEUROPATHY: STRUCTURAL AND FUNCTIONAL EVIDENCES

INDIAN DRUGS ◽

10.53879/id.54.11.10855 ◽

2017 ◽

Vol 54 (11) ◽

pp. 58-60

Author(s):

N Solanki ◽

◽

S. K Bhavsar

Keyword(s):

Sciatic Nerve ◽

Diabetic Neuropathy ◽

Ethanolic Extract ◽

Protective Role ◽

Diabetic Rats ◽

Dependent Manner ◽

Traditional System ◽

Ficus Racemosa ◽

Dose Dependent

Ficus racemosa is used in traditional system of medicine for various health problems and diseases, and is commonly known as Gular fig. The main objective was to study its effects against streptozotocin induced diabetic neuropathy by structural and functional marker. Investigation of diabetic neuropathy was carried out through functional and structural assessment in streptozotocin induced in diabetic rats. Diabetic rats were treated for 28 days in dose dependent manner of Ficus racemosa aqueous extract (250 mg/kg and 500 mg/kg) and ethanolic extract (200 mg/kg and 400 mg/kg). Study showed marked protection observed by Ficus racemosa in hippocampus region of brain and sciatic nerve tissues. Ficus racemosa treatment showed improvement in functional and structural markers, which strongly suggest its protective role in diabetic neuropathy.

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