Steroid-resistant autoimmune myelofibrosis in a patient with autoimmune hepatitis and Evans syndrome complicated with increased expression of TGF-β in the bone marrow: a case report

2017 ◽  
Vol 106 (5) ◽  
pp. 718-724
Author(s):  
Hiroshi Ohkawara ◽  
Miki Furukawa ◽  
Kazuhiko Ikeda ◽  
Akiko Shichishima-Nakamura ◽  
Masahiko Fukatsu ◽  
...  
2021 ◽  
Author(s):  
Kenta Yoshida ◽  
Takao Oyama ◽  
Takenori Takahata ◽  
Sae Kudo ◽  
Yuki Sato ◽  
...  

2006 ◽  
Vol 27 (5) ◽  
pp. 489-491 ◽  
Author(s):  
Feng-Cheng Liu ◽  
Deh-Ming Chang ◽  
Jenn-Haung Lai ◽  
Chih-Kung Lin ◽  
Hsiang-Cheng Chen ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Samin Alavi ◽  
Maryam Ebadi ◽  
Alireza Jenabzadeh ◽  
M. T. Arzanian ◽  
Sh. Shamsian

Herein, the first case of childhood erythrophagocytosis following chemotherapy for erythroleukemia in a child with monosomy 7 is reported. A 5-year-old boy presented with anemia, thrombocytopenia, and hepatosplenomegaly in whom erythroleukemia was diagnosed. Prolonged pancytopenia accompanied by persistent fever and huge splenomegaly and hepatomegaly became evident after 2 courses of chemotherapy. On bone marrow aspiration, macrophages phagocytosing erythroid precursors were observed and the diagnosis of HLH was established; additionally, monosomy 7 was detected on bone marrow cytogenetic examination. In conclusion, monosomy 7 can lead to erythrophagocytosis associated with erythroid leukemia and should be considered among the chromosomal abnormalities contributing to the association.


2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Pankit Vachhani ◽  
Prithviraj Bose

Myeloid sarcoma represents the proliferation of myeloblasts of acute myeloid leukemia (AML) at extramedullary sites. While extramedullary involvement in AML is uncommon in itself, isolated myeloid sarcomas, that is, myeloid sarcomas without any bone marrow involvement, are extremely rare and pose a diagnostic and therapeutic challenge. Here, we present the case of a middle-aged woman with isolated myeloid sarcoma in the stomach—an organ seldom involved by this disease. Additionally, the literature on the epidemiology, diagnosis, pathology, prognosis, and therapeutic options in myeloid sarcomas has been reviewed.


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