Preparation of Citric Acid-Locust Bean Gum (CA-LBG) for the Disintegrating Agent of Tablet Dosage Forms

2021 ◽  
Author(s):  
Wuryanto Hadinugroho ◽  
Suwaldi Martodihardjo ◽  
Achmad Fudholi ◽  
Sugeng Riyanto
Keyword(s):  
Citric Acid ◽  
Dosage Forms ◽  
Locust Bean Gum ◽  
Locust Bean ◽  
Tablet Dosage

scholarly journals Esterification of citric acid with locust bean gum

Heliyon ◽  
2019 ◽  
Vol 5 (8) ◽  
pp. e02337
Author(s):  
Wuryanto Hadinugroho ◽  
Suwaldi Martodihardjo ◽  
Achmad Fudholi ◽  
Sugeng Riyanto
Keyword(s):  
Citric Acid ◽  
Locust Bean Gum ◽  
Locust Bean

scholarly journals Effect of composition changes and aeration time on the structure and rehydration of innovative freeze-dried gels

2018 ◽  
Vol 32 (3) ◽  
pp. 429-435 ◽  
Author(s):  
Agnieszka Ciurzyńska ◽  
Agata Pisarska ◽  
Ignacy Olsiński ◽  
Anna Maria Panfiluk ◽  
Magdalena Sylwia Ostap ◽  
...  
Keyword(s):  
Citric Acid ◽  
Xanthan Gum ◽  
Guar Gum ◽  
Structural Effect ◽  
Locust Bean Gum ◽  
Aeration Time ◽  
Freeze Dried ◽  
Locust Bean ◽  
Pectin Gels ◽  
Composition Changes

Abstract This paper seeks to explain the structural effect on selected properties of freeze-dried gels with different compositions and aeration times. Herein, sugars and citric acid were added to gels with low-methoxyl pectin, mixtures of xanthan gum and locust bean gum, as well as xanthan gum and guar gum, in order to obtain a strawberry model. Strawberry pulp was also added to hydrocolloids to develop an innovative strawberry product. All samples were aerated for 3 and 7 min, and freeze-dried. Composition changes were found to modify the structure of the examined samples and properties. Freeze-dried gels with low-methoxyl pectin seemed to reflect the best approach towards obtaining an innovative strawberry product with a tailored structure, as they had the best water absorbent capacity, and the most attractive and delicate structure. Samples with a mixture of hydrocolloids were more compact. Aeration time did not significantly affect the examined parameters, while the addition of sugar and citric acid increased them. The strawberry pulp experiment confirmed the strawberry model (with low-methoxyl pectin gels, and sugar and citric acid), which had the finest structure and the best rehydration properties.

A validated densitometric TLC method for analysis of cefuroxime axetil and potassium clavulanate in combined tablet dosage forms

2010 ◽  
Vol 22 (1) ◽  
pp. 91-97 ◽  
Author(s):  
M. R. Sengar ◽  
S. V. Gandhi ◽  
U. P. Patil ◽  
V. S. Rajmane ◽  
K. G. Bothara
Keyword(s):  
Cefuroxime Axetil ◽  
Dosage Forms ◽  
Potassium Clavulanate ◽  
Tablet Dosage

Plantago Ovata and Locust Bean Gum as a Natural Polymer in Hydrodynamically Balanced Systems: A Review

2020 ◽  
Author(s):  
Ghildiyal s
Keyword(s):  
Drug Delivery ◽  
Locust Bean Gum ◽  
Main Role ◽  
Natural Polymer ◽  
Release Formulation ◽  
Sustained Drug Delivery ◽  
Modern Drug ◽  
Buccal Drug Delivery ◽  
Locust Bean ◽  
Ceratonia Siliqua L

Hydrodynamically Balanced systems have wide development as they have achieved the parameters of modern drug delivery system, it is a type of system which owes very tremendous and curative benefits for the delivery of oral controlled release dosage forms and have wide properties in many aspects such as its main role is to maintain the effective concentration in the system for longer period of time. To reduce the gastric mucosal irritation due to the presence of synthetic polymers, being a natural polymer incorporation of Plantago ovate (Psyllium Husk) could ease out the mucosal irritation in the gastric region. Due to its properties such as a rate-controlling polymer possessing a very good quality of swelling and good gelling nature, and also incorporated as a matrix-forming agent basically in the modified release formulation. Locust bean gum can be used as sustained-release carriers and release modifiers for the delivery of drugs. It is a neutral plant galactomannan extracted from the seeds (kernels) of the carob tree Ceratonia siliqua L fabaceae. Nowadays it is focussing polymer and a lot of researchers are focussing on exploring the potential in topical drug delivery, colonic drug delivery, oral sustained drug delivery, ocular drug delivery, buccal drug delivery.

Effect of locust bean gum and konjac glucomannan oh the conformation and rheology of agarose and ?-carrageenan

Biopolymers ◽  
1995 ◽  
Vol 36 (5) ◽  
pp. 643-658 ◽  
Author(s):  
F. M. Goycoolea ◽  
R. K. Richardson ◽  
E. R. Morris ◽  
M. J. Gidley
Keyword(s):  
Konjac Glucomannan ◽  
Locust Bean Gum ◽  
Locust Bean

scholarly journals A new stability-indicating RP-HPLC method for the determination of dicyclomine hydrochloride and dimethicone combination in tablet dosage forms

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
J. Saroja ◽  
Anantha Lakshmi P.V. ◽  
Y. Rammohan ◽  
D. Divya Reddy
Keyword(s):  
Liquid Chromatography ◽  
Dosage Forms ◽  
Flow Speed ◽  
Hplc Method ◽  
Stability Indicating ◽  
Simultaneous Quantification ◽  
Rp Hplc ◽  
Tablet Formulations ◽  
Tablet Dosage

Abstract Background We describe a “stability-indicating liquid chromatography” technique for the estimation of dimethicone (DEC) and dicyclomine hydrochloride (DEH) in the established tablet formulations. Individual quantification of DEH and DEC was reported. But simultaneous quantification of DEH and DEC was lacking. DEH and DEC were analysed on an “XTerra C18 column (250 mm × 4.6 mm, 5 μm)” with the mobile phase solvent run isocratically with 0.1M K2HPO4-acetonitrile (55:45, v/v) on a flow speed of 1.0 mL/min. Results The chromatographic run period for the DEC and DEH assay was 6.0 min with retention times of 2.134 and 2.865 min, respectively. The method was validated for accuracy (99.453 to 100.417% and 99.703 to 100.303% recovery values for DEH and DEC, respectively), precision (RSV value 0.135% for DEC and 0.171% for DEH), linearity (5–15 μg/mL for DEH and 20–60 μg/mL for DEC), selectivity (no hinderance from excipients) and specificity (no hinderance from degradants) recovery. Conclusion The developed stability-indicating liquid chromatography process was well applied to established tablet formulations.

Jam processing: Effect of pectin replacement by locust bean gum on its characteristics

2020 ◽  
pp. 1-12
Author(s):  
Aida Mekhoukhe ◽  
Nacer Mohellebi ◽  
Tayeb Mohellebi ◽  
Leila Deflaoui-Abdelfettah ◽  
Sonia Medouni-Adrar ◽  
...  
Keyword(s):  
Cold Water ◽  
Physicochemical Characteristics ◽  
Water Soluble ◽  
Sensory Profile ◽  
Locust Bean Gum ◽  
Locust Bean ◽  
Preference Map ◽  
The Right ◽  
High Level ◽  
The Impact

OBJECTIVE: the present work proposed to extract Locust Bean Gum (LBG) from Algerian carob fruits, evaluate physicochemical and rheological properties (solubility). It aimed also to develop different formulations of strawberry jams with a mixture of LBG and pectin in order to obtain a product with a high sensory acceptance. METHODS: the physicochemical characteristics of LBG were assessed. The impact of temperature on solubility was also studied. The physical and the sensory profile and acceptance of five Jams were evaluated. RESULTS: composition results revealed that LBG presented a high level of carbohydrate but low concentrations of fat and ash. The LBG was partially cold-water-soluble (∼62% at 25°C) and needed heating to reach a higher solubility value (∼89% at 80 °C). Overall, the sensorial acceptances decreased in jams J3 which was formulated with 100% pectin and commercial one (J5). The external preference map explained that most consumers were located to the right side of the map providing evidence that most samples appreciated were J4 and J2 (rate of 80–100%). CONCLUSION: In this investigation, the LBG was used successfully in the strawberry jam’s formulation.

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