scholarly journals Classification of COVID-19 by Compressed Chest CT Image through Deep Learning on a Large Patients Cohort

2021 ◽  
Vol 13 (1) ◽  
pp. 73-82
Author(s):  
Ziwei Zhu ◽  
Zhang Xingming ◽  
Guihua Tao ◽  
Tingting Dan ◽  
Jiao Li ◽  
...  
Keyword(s):  
Deep Learning ◽  
Chest Ct ◽  
Ct Image

COVID-19 pneumonia diagnosis using a simple 2D deep learning framework with a single chest CT image (Preprint)

2020 ◽  
Author(s):  
Jinseok Lee
Keyword(s):  
Deep Learning ◽  
Diagnostic Performance ◽  
Ct Images ◽  
Chest Ct ◽  
University Hospital ◽  
Detection Accuracy ◽  
Ct Image ◽  
Test Dataset ◽  
Learning Framework ◽  
Testing Dataset

BACKGROUND The coronavirus disease (COVID-19) has explosively spread worldwide since the beginning of 2020. According to a multinational consensus statement from the Fleischner Society, computed tomography (CT) can be used as a relevant screening tool owing to its higher sensitivity for detecting early pneumonic changes. However, physicians are extremely busy fighting COVID-19 in this era of worldwide crisis. Thus, it is crucial to accelerate the development of an artificial intelligence (AI) diagnostic tool to support physicians. OBJECTIVE We aimed to quickly develop an AI technique to diagnose COVID-19 pneumonia and differentiate it from non-COVID pneumonia and non-pneumonia diseases on CT. METHODS A simple 2D deep learning framework, named fast-track COVID-19 classification network (FCONet), was developed to diagnose COVID-19 pneumonia based on a single chest CT image. FCONet was developed by transfer learning, using one of the four state-of-art pre-trained deep learning models (VGG16, ResNet50, InceptionV3, or Xception) as a backbone. For training and testing of FCONet, we collected 3,993 chest CT images of patients with COVID-19 pneumonia, other pneumonia, and non-pneumonia diseases from Wonkwang University Hospital, Chonnam National University Hospital, and the Italian Society of Medical and Interventional Radiology public database. These CT images were split into a training and a testing set at a ratio of 8:2. For the test dataset, the diagnostic performance to diagnose COVID-19 pneumonia was compared among the four pre-trained FCONet models. In addition, we tested the FCONet models on an additional external testing dataset extracted from the embedded low-quality chest CT images of COVID-19 pneumonia in recently published papers. RESULTS Of the four pre-trained models of FCONet, the ResNet50 showed excellent diagnostic performance (sensitivity 99.58%, specificity 100%, and accuracy 99.87%) and outperformed the other three pre-trained models in testing dataset. In additional external test dataset using low-quality CT images, the detection accuracy of the ResNet50 model was the highest (96.97%), followed by Xception, InceptionV3, and VGG16 (90.71%, 89.38%, and 87.12%, respectively). CONCLUSIONS The FCONet, a simple 2D deep learning framework based on a single chest CT image, provides excellent diagnostic performance in detecting COVID-19 pneumonia. Based on our testing dataset, the ResNet50-based FCONet might be the best model, as it outperformed other FCONet models based on VGG16, Xception, and InceptionV3.

scholarly journals Deep Learning Method for Quantitative Analysis of Covid -19 using CT Chest Images

2021 ◽  
Author(s):  
Indrajeet Kumar ◽  
Jyoti Rawat
Keyword(s):  
Deep Learning ◽  
Diagnostic Tests ◽  
Ct Images ◽  
Rapid Diagnosis ◽  
Chest Ct ◽  
Visual Features ◽  
Learning Module ◽  
Volumetric Ct ◽  
The Cost

Abstract The manual diagnostic tests performed in laboratories for pandemic disease such as COVID19 is time-consuming, requires skills and expertise of the performer to yield accurate results. Moreover, it is very cost ineffective as the cost of test kits is high and also requires well-equipped labs to conduct them. Thus, other means of diagnosing the patients with presence of SARS-COV2 (the virus responsible for COVID19) must be explored. A radiography method like chest CT images is one such means that can be utilized for diagnosis of COVID19. The radio-graphical changes observed in CT images of COVID19 patient helps in developing a deep learning-based method for extraction of graphical features which are then used for automated diagnosis of the disease ahead of laboratory-based testing. The proposed work suggests an Artificial Intelligence (AI) based technique for rapid diagnosis of COVID19 from given volumetric CT images of patient’s chest by extracting its visual features and then using these features in the deep learning module. The proposed convolutional neural network is deployed for classifying the infectious and non-infectious SARS-COV2 subjects. The proposed network utilizes 746 chests scanned CT images of which 349 images belong to COVID19 positive cases while remaining 397 belong negative cases of COVID19. The extensive experiment has been completed with the accuracy of 98.4 %, sensitivity of 98.5 %, the specificity of 98.3 %, the precision of 97.1 %, F1score of 97.8 %. The obtained result shows the outstanding performance for classification of infectious and non-infectious for COVID19 cases.

Intelligent classification of lung malignancies using deep learning techniques

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Priyanka Yadlapalli ◽  
D. Bhavana ◽  
Suryanarayana Gunnam
Keyword(s):  
Lung Cancer ◽  
Deep Learning ◽  
Ct Scan ◽  
Transfer Learning ◽  
Confusion Matrix ◽  
Chest Ct ◽  
Lung Nodules ◽  
Content Type ◽  
Chest Ct Scan

PurposeComputed tomography (CT) scan can provide valuable information in the diagnosis of lung diseases. To detect the location of the cancerous lung nodules, this work uses novel deep learning methods. The majority of the early investigations used CT, magnetic resonance and mammography imaging. Using appropriate procedures, the professional doctor in this sector analyses these images to discover and diagnose the various degrees of lung cancer. All of the methods used to discover and detect cancer illnesses are time-consuming, expensive and stressful for the patients. To address all of these issues, appropriate deep learning approaches for analyzing these medical images, which included CT scan images, were utilized.Design/methodology/approachRadiologists currently employ chest CT scans to detect lung cancer at an early stage. In certain situations, radiologists' perception plays a critical role in identifying lung melanoma which is incorrectly detected. Deep learning is a new, capable and influential approach for predicting medical images. In this paper, the authors employed deep transfer learning algorithms for intelligent classification of lung nodules. Convolutional neural networks (VGG16, VGG19, MobileNet and DenseNet169) are used to constrain the input and output layers of a chest CT scan image dataset.FindingsThe collection includes normal chest CT scan pictures as well as images from two kinds of lung cancer, squamous and adenocarcinoma impacted chest CT scan images. According to the confusion matrix results, the VGG16 transfer learning technique has the highest accuracy in lung cancer classification with 91.28% accuracy, followed by VGG19 with 89.39%, MobileNet with 85.60% and DenseNet169 with 83.71% accuracy, which is analyzed using Google Collaborator.Originality/valueThe proposed approach using VGG16 maximizes the classification accuracy when compared to VGG19, MobileNet and DenseNet169. The results are validated by computing the confusion matrix for each network type.

scholarly journals Using Deep Learning for Classification of Lung Nodules on Computed Tomography Images

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
QingZeng Song ◽  
Lei Zhao ◽  
XingKe Luo ◽  
XueChen Dou
Keyword(s):  
Lung Cancer ◽  
Deep Learning ◽  
Deep Neural Networks ◽  
Lung Nodules ◽  
Ct Image ◽  
Powerful Method ◽  
Imaging Diagnosis ◽  
Computed Tomography Images ◽  
Common Cancer

Lung cancer is the most common cancer that cannot be ignored and cause death with late health care. Currently, CT can be used to help doctors detect the lung cancer in the early stages. In many cases, the diagnosis of identifying the lung cancer depends on the experience of doctors, which may ignore some patients and cause some problems. Deep learning has been proved as a popular and powerful method in many medical imaging diagnosis areas. In this paper, three types of deep neural networks (e.g., CNN, DNN, and SAE) are designed for lung cancer calcification. Those networks are applied to the CT image classification task with some modification for the benign and malignant lung nodules. Those networks were evaluated on the LIDC-IDRI database. The experimental results show that the CNN network archived the best performance with an accuracy of 84.15%, sensitivity of 83.96%, and specificity of 84.32%, which has the best result among the three networks.

scholarly journals NSCR-Based DenseNet for Lung Tumor Recognition Using Chest CT Image

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Zhou Tao ◽  
Huo Bingqiang ◽  
Lu Huiling ◽  
Yang Zaoli ◽  
Shi Hongbin
Keyword(s):  
Lung Tumor ◽  
Coefficient Matrix ◽  
Chest Ct ◽  
Collaborative Representation ◽  
Ct Image ◽  
Evaluation Indexes ◽  
Specificity And Sensitivity ◽  
Tumor Recognition ◽  
Medical Analysis

Nonnegative sparse representation has become a popular methodology in medical analysis and diagnosis in recent years. In order to resolve network degradation, higher dimensionality in feature extraction, data redundancy, and other issues faced when medical images parameters are trained using convolutional neural networks. Lung tumors in chest CT image based on nonnegative, sparse, and collaborative representation classification of DenseNet (DenseNet-NSCR) are proposed by this paper: firstly, initialization parameters of pretrained DenseNet model using transfer learning; secondly, training DenseNet using CT images to extract feature vectors for the full connectivity layer; thirdly, a nonnegative, sparse, and collaborative representation (NSCR) is used to represent the feature vector and solve the coding coefficient matrix; fourthly, the residual similarity is used for classification. The experimental results show that the DenseNet-NSCR classification is better than the other models, and the various evaluation indexes such as specificity and sensitivity are also high, and the method has better robustness and generalization ability through comparison experiment using AlexNet, GoogleNet, and DenseNet-201 models.

scholarly journals COVID-19 Pneumonia Diagnosis Using a Simple 2D Deep Learning Framework With a Single Chest CT Image: Model Development and Validation (Preprint)

2020 ◽  
Author(s):  
Hoon Ko ◽  
Heewon Chung ◽  
Wu Seong Kang ◽  
Kyung Won Kim ◽  
Youngbin Shin ◽  
...  
Keyword(s):  
Deep Learning ◽  
Diagnostic Performance ◽  
Ct Images ◽  
Chest Ct ◽  
University Hospital ◽  
Detection Accuracy ◽  
Ct Image ◽  
Data Set ◽  
Learning Framework ◽  
Testing Data

BACKGROUND Coronavirus disease (COVID-19) has spread explosively worldwide since the beginning of 2020. According to a multinational consensus statement from the Fleischner Society, computed tomography (CT) is a relevant screening tool due to its higher sensitivity for detecting early pneumonic changes. However, physicians are extremely occupied fighting COVID-19 in this era of worldwide crisis. Thus, it is crucial to accelerate the development of an artificial intelligence (AI) diagnostic tool to support physicians. OBJECTIVE We aimed to rapidly develop an AI technique to diagnose COVID-19 pneumonia in CT images and differentiate it from non–COVID-19 pneumonia and nonpneumonia diseases. METHODS A simple 2D deep learning framework, named the fast-track COVID-19 classification network (FCONet), was developed to diagnose COVID-19 pneumonia based on a single chest CT image. FCONet was developed by transfer learning using one of four state-of-the-art pretrained deep learning models (VGG16, ResNet-50, Inception-v3, or Xception) as a backbone. For training and testing of FCONet, we collected 3993 chest CT images of patients with COVID-19 pneumonia, other pneumonia, and nonpneumonia diseases from Wonkwang University Hospital, Chonnam National University Hospital, and the Italian Society of Medical and Interventional Radiology public database. These CT images were split into a training set and a testing set at a ratio of 8:2. For the testing data set, the diagnostic performance of the four pretrained FCONet models to diagnose COVID-19 pneumonia was compared. In addition, we tested the FCONet models on an external testing data set extracted from embedded low-quality chest CT images of COVID-19 pneumonia in recently published papers. RESULTS Among the four pretrained models of FCONet, ResNet-50 showed excellent diagnostic performance (sensitivity 99.58%, specificity 100.00%, and accuracy 99.87%) and outperformed the other three pretrained models in the testing data set. In the additional external testing data set using low-quality CT images, the detection accuracy of the ResNet-50 model was the highest (96.97%), followed by Xception, Inception-v3, and VGG16 (90.71%, 89.38%, and 87.12%, respectively). CONCLUSIONS FCONet, a simple 2D deep learning framework based on a single chest CT image, provides excellent diagnostic performance in detecting COVID-19 pneumonia. Based on our testing data set, the FCONet model based on ResNet-50 appears to be the best model, as it outperformed other FCONet models based on VGG16, Xception, and Inception-v3.

scholarly journals COVID-19 Pneumonia Diagnosis Using a Simple 2D Deep Learning Framework With a Single Chest CT Image: Model Development and Validation

10.2196/19569 ◽  
2020 ◽  
Vol 22 (6) ◽  
pp. e19569 ◽  
Author(s):  
Hoon Ko ◽  
Heewon Chung ◽  
Wu Seong Kang ◽  
Kyung Won Kim ◽  
Youngbin Shin ◽  
...  
Keyword(s):  
Deep Learning ◽  
Diagnostic Performance ◽  
Ct Images ◽  
Chest Ct ◽  
University Hospital ◽  
Detection Accuracy ◽  
Ct Image ◽  
Data Set ◽  
Learning Framework ◽  
Testing Data

Background Coronavirus disease (COVID-19) has spread explosively worldwide since the beginning of 2020. According to a multinational consensus statement from the Fleischner Society, computed tomography (CT) is a relevant screening tool due to its higher sensitivity for detecting early pneumonic changes. However, physicians are extremely occupied fighting COVID-19 in this era of worldwide crisis. Thus, it is crucial to accelerate the development of an artificial intelligence (AI) diagnostic tool to support physicians. Objective We aimed to rapidly develop an AI technique to diagnose COVID-19 pneumonia in CT images and differentiate it from non–COVID-19 pneumonia and nonpneumonia diseases. Methods A simple 2D deep learning framework, named the fast-track COVID-19 classification network (FCONet), was developed to diagnose COVID-19 pneumonia based on a single chest CT image. FCONet was developed by transfer learning using one of four state-of-the-art pretrained deep learning models (VGG16, ResNet-50, Inception-v3, or Xception) as a backbone. For training and testing of FCONet, we collected 3993 chest CT images of patients with COVID-19 pneumonia, other pneumonia, and nonpneumonia diseases from Wonkwang University Hospital, Chonnam National University Hospital, and the Italian Society of Medical and Interventional Radiology public database. These CT images were split into a training set and a testing set at a ratio of 8:2. For the testing data set, the diagnostic performance of the four pretrained FCONet models to diagnose COVID-19 pneumonia was compared. In addition, we tested the FCONet models on an external testing data set extracted from embedded low-quality chest CT images of COVID-19 pneumonia in recently published papers. Results Among the four pretrained models of FCONet, ResNet-50 showed excellent diagnostic performance (sensitivity 99.58%, specificity 100.00%, and accuracy 99.87%) and outperformed the other three pretrained models in the testing data set. In the additional external testing data set using low-quality CT images, the detection accuracy of the ResNet-50 model was the highest (96.97%), followed by Xception, Inception-v3, and VGG16 (90.71%, 89.38%, and 87.12%, respectively). Conclusions FCONet, a simple 2D deep learning framework based on a single chest CT image, provides excellent diagnostic performance in detecting COVID-19 pneumonia. Based on our testing data set, the FCONet model based on ResNet-50 appears to be the best model, as it outperformed other FCONet models based on VGG16, Xception, and Inception-v3.

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