Ferrous Iron Overload Evokes Thyroidal and Interrenal Activation, Shifts Metabolite Pattern and Reverses Hepatic Ion Transporter Activities in Salinity-Acclimated Air-Breathing Fish (Anabas testudineus) Bloch

2021 ◽  
Author(s):  
R. Gayathry ◽  
Valsa S. Peter ◽  
M. C. Subhash Peter
Keyword(s):  
Iron Overload ◽  
Ferrous Iron ◽  
Anabas Testudineus ◽  
Air Breathing ◽  
Ion Transporter ◽  
Metabolite Pattern

scholarly journals Is Boldness in Climbing Perch (Anabas testudineus) Sensitive to the Apparatus Used for Measurement?

2020 ◽  
Author(s):  
Prantik Das ◽  
V V Binoy
Keyword(s):  
Freshwater Fish ◽  
Open Field ◽  
Water Surface ◽  
Repeated Exposure ◽  
Anabas Testudineus ◽  
Air Breathing ◽  
Climbing Perch ◽  
Water Plant ◽  
The Subject ◽  
The Impact

AbstractSwimway and open field are the two popular apparatus used for measuring boldness - the propensity to take risky decisions - in various piscine species. The present study compared boldness exhibited by an air breathing freshwater fish climbing perch in a swimway, rectangular open field, intermediate stages between these two apparatus and circular open field. Impact of the modification of the start chamber by providing substratum made up of cobbles and covering the water surface using water plant hydrilla, alone and in combinations on the boldness was also tested. Our results revealed that the apparatus has a significant impact on the boldness in climbing perch. The presence of a shelter in the experimental arena (swimway) and cobble substratum in the start chamber of the apparatus were found to be reducing boldness in this fish, while hydrilla cover on the water surface neutralised the impact of cobble substratum. Repeated exposure and resultant familiarity with the arena increased boldness of climbing perch but the pattern of modification of this behavioural trait exhibited during the course of experiment was divergent across the instruments. These results point towards the need for critically analyzing the influence of instruments used for measuring various behavioural traits and considering biological needs of the subject species while designing the apparatus.

scholarly journals Heme Oxygenase-1 Regulates Ferrous Iron and Foxo1 in Control of Hepatic Gluconeogenesis

2021 ◽  
Author(s):  
Ada Admin ◽  
Wang Liao ◽  
Wanbao Yang ◽  
Zheng Shen ◽  
Weiqi Ai ◽  
...  
Keyword(s):  
Iron Overload ◽  
Heme Oxygenase ◽  
Ferrous Iron ◽  
Iron Status ◽  
Hepatic Glucose Production ◽  
Glucose Production ◽  
Iron Chelator ◽  
Heme Oxygenase 1 ◽  
Dependent Manner

The liver is a key player for maintaining glucose homeostasis. Excessive hepatic glucose production is considered to be a key for the onset of type 2 diabetes mellitus. The primary function of heme oxygenase-1 (HO1) is to catalyze the degradation of heme into biliverdin, ferrous iron, and carbon monoxide. Previous studies have demonstrated that the degradation of heme by HO1 in the liver results in mitochondrial dysfunction and drives insulin resistance. In this study, by overexpressing HO1 in hepatocytes and mice, we showed that HO1 promotes gluconeogenesis in a Foxo1-dependent manner. Importantly, HO1 overexpression increased the generation of ferrous iron in the liver, which further activates NF-<a>κB</a> and phosphorylates Foxo1 at Ser273 to enhance gluconeogenesis. We further assessed the role of HO1 in insulin-resistant L-DKO (liver-specific knockout of IRS1 and IRS2 genes) mice, which exhibit upregulation of HO1 in the liver and hepatic ferrous iron overload. HO1 knockdown by shRNA or treatment of iron chelator rescued the aberrant gluconeogenesis in L-DKO mice. In addition, we found that systemic iron overload promotes gluconeogenesis by activating hepatic PKA→Foxo1 axis. Thus, our results demonstrate the role of HO1 in regulating hepatic iron status and Foxo1 to control gluconeogenesis and blood glucose.

scholarly journals The effect of seasonal temperature on endogenous gut enzyme activity in four air-breathing fish species

2018 ◽  
Vol 76 (2) ◽  
pp. 60-65 ◽  
Author(s):  
Goutam Banerjee ◽  
Arun Kumar Ray
Keyword(s):  
Enzyme Activity ◽  
Fish Species ◽  
Feeding Habits ◽  
Seasonal Temperature ◽  
Anabas Testudineus ◽  
Air Breathing ◽  
Wide Range ◽  
Exogenous Enzymes ◽  
Feeding Regimes ◽  
The Cost

Abstract The digestion process in fish is a complex phenomenon and is accomplished with the help of both endogenous and exogenous enzymes. A wide range of enzymes have been reported in fish and their secretion and concentrations highly depend on feeding habits, gut structure and environmental conditions. In this present investigation, we have demonstrated the activity of two endogenous enzymes (protease and amylase) in four economically important air-breathing fish species (Clarias batrachus, Channa punctatus, Anabas testudineus and Heteropneustes fossilis) at different seasonal temperatures. Our results demonstrated that protease activity was higher in all fish during the month of May, followed by September and December. It was also detected that enzyme activity was higher in the hindgut region (HG) compared to the foregut (FG), which suggests that HG is more active in digestion compared to FG. The optimization of feeding efficiency in aquaculture industries is very important, as the cost of feed is high and its availability is also limited. The information presented may be of importance when developing optimized diets and feeding regimes for the species considered.

scholarly journals Clinical and Histopathological Study of Important Air-Breathing Fishes

2013 ◽  
Vol 19 (1) ◽  
pp. 69-78 ◽  
Author(s):  
ZP Patwary ◽  
MAR Faruk ◽  
MM Ali
Keyword(s):  
Clinical Signs ◽  
Inflammatory Cells ◽  
Histopathological Study ◽  
Cell Debris ◽  
Anabas Testudineus ◽  
Air Breathing ◽  
Liver And Kidney ◽  
Health And Disease ◽  
Massive Necrosis ◽  
Gill Lamellae

A study was conducted to know the health and disease problems of three important air-breathing fishes viz. Shing (Heteropneustes fossilis), Magur (Clarias batrachus) and Thai Koi (Anabas testudineus) through clinical and histopathological technique from June 2007 to March 2008 collected from selected farms and from local markets. Generally, during December and January, acute pathologies were recorded. Clinical signs of Shing included haemorrhage, extended belly and ulceration. Histopathologically, partly missing and splitted epidermis and dermis, necrotic, vacuoled and ruptured myotomes of muscle with fungal granuloma were observed. Major gill pathologies included partly missing and highly hypertrophied, haemorrhagic gill lamellae, presence of monogenetic trematode and pyknotic cells. In liver, haemorrhagic areas, necrotic, vacuoled, hyperplasid hepatocytes, cell debris, pyknotic nuclei and plenty of inflammatory cells were evident. Haemorrhages, vacuolation, necrosis, missing and ruptured kidney tubules and pyknotic nuclei were the major pathologies of kidney. Clinically, dark red lesion, haemorrhage, necrosis and ulcer in body surface were seen in Magur. Histopathologically observed pathologies in Magur were almost similar to that of Shing. Clinical signs of Thai Koi included discoloration, loss of scales and fins, abnormal caudal fin, haemorrhage in gill and ulcer. Marked histopathology in the skin and muscle were observed such as totally lost epidermis, dermis separated from muscle, severely ruptured, degenerated and missing of myotomes in many places. In gills, hypertrophy, hyperplasia, telangiectasis, clubbing, haemorrhage and massive necrosis in both primary and secondary gill lamellae were found. Pathologies observed in liver and kidney were most alike to that of Shing. In the months of February and March, all the investigated organs of the three fish species were at a healing stage.DOI: http://dx.doi.org/10.3329/pa.v19i1.17109 Progress. Agric. 19(1): 69 - 78, 2008 

Sign in / Sign up

Export Citation Format

Share Document