Dietary restriction of lycopene for a period of one month resulted in significantly increased biomarkers of oxidative stress and bone resorption in postmenopausal women

2011 ◽  
Vol 15 (2) ◽  
pp. 133-138 ◽  
Author(s):  
E. S. Mackinnon ◽  
A. venket Rao ◽  
L. G. Rao
Keyword(s):  
Oxidative Stress ◽  
Bone Resorption ◽  
Postmenopausal Women ◽  
Dietary Restriction ◽  
Biomarkers Of Oxidative Stress

Effects of daily blueberry consumption on circulating biomarkers of oxidative stress, inflammation, and antioxidant defense in postmenopausal women with pre- and stage 1-hypertension: a randomized controlled trial

2017 ◽  
Vol 8 (1) ◽  
pp. 372-380 ◽  
Author(s):  
Sarah A. Johnson ◽  
Rafaela G. Feresin ◽  
Negin Navaei ◽  
Arturo Figueroa ◽  
Marcus L. Elam ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Postmenopausal Women ◽  
Antioxidant Defense ◽  
Controlled Trial ◽  
Disease Development ◽  
Circulating Biomarkers ◽  
Randomized Controlled ◽  
Age Related ◽  
Stage 1 ◽  
Biomarkers Of Oxidative Stress

Blueberries may attenuate accelerated age-related chronic disease development in postmenopausal women.

scholarly journals Association Between Global Biomarkers of Oxidative Stress and Hip Fracture in Postmenopausal Women: A Prospective Study

2014 ◽  
Vol 29 (12) ◽  
pp. 2577-2583 ◽  
Author(s):  
Shuman Yang ◽  
Diane Feskanich ◽  
Walter C Willett ◽  
A Heather Eliassen ◽  
Tianying Wu
Keyword(s):  
Oxidative Stress ◽  
Hip Fracture ◽  
Prospective Study ◽  
Postmenopausal Women ◽  
A Prospective Study ◽  
Biomarkers Of Oxidative Stress

Lycopene consumption decreases oxidative stress and bone resorption markers in postmenopausal women

2006 ◽  
Vol 18 (1) ◽  
pp. 109-115 ◽  
Author(s):  
L. G. Rao ◽  
E. S. Mackinnon ◽  
R. G. Josse ◽  
T. M. Murray ◽  
A. Strauss ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Bone Resorption ◽  
Postmenopausal Women ◽  
Bone Resorption Markers

scholarly journals Female Reproductive Hormones and Biomarkers of Oxidative Stress in Postmenopausal Women With Breast Cancer

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 58s-58s
Author(s):  
A.C. Nsonwu-Anyanwu ◽  
A. Usoro ◽  
S.J. Offor ◽  
C.A.O. Usoro
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Nitric Oxide ◽  
Postmenopausal Women ◽  
Reproductive Hormones ◽  
Clinical Staging ◽  
Stress Index ◽  
Breast Lump ◽  
Oxidative Stress Index ◽  
Biomarkers Of Oxidative Stress

Background: Female reproductive hormones have been implicated in the etiology of breast cancer, while oxidative stress induced by reactive oxygen species have been linked to various steps involved in carcinogenesis including cellular transformation, proliferation and metastasis. Aim: This study assessed the serum levels of estradiol (E2), prolactin (PRL) and some biomarkers of oxidative stress in relation with clinical staging in postmenopausal women with breast cancer. Methods: One hundred postmenopausal women aged 50 to 70 years comprising of 50 women with breast cancer (with clinical staging II-IV) and 50 healthy women without breast lump or cancer were recruited into this case control study. Estradiol and prolactin were determined by enzyme linked immunosorbent assay, total antioxidant capacity (TAC), total plasma peroxides (TPP), malondialdehyde (MDA), glutathione (GSH) and nitric oxide (NO) were estimated by colorimetric methods while oxidative stress index was determined by calculation. Sociodemographic data and anthropometric indices (body mass index (BMI)) were obtained by standard methods. Data were analyzed using Student t-test, ANOVA and Pearson's correlation at P < 0.05. Results: The percentage of women with breast lump, breast pain, nipple discharge, high alcohol and fat intake were higher in women with breast cancer compared with women without breast cancer ( P < 0.05). The mean age at menarche, TAC, TPP, OSI, NO and E2 levels were significantly lower and BMI higher in controls compared with breast cancer subjects ( P < 0.05). Women without breast cancer had lower TPP, OSI and E2 compared with stage II; lower TAC, TPP, NO and E2 compared with stage II; and lower MDA, NO and E2 compared with stage 4 respectively ( P < 0.05). Positive correlations were observed between PRL and TAC (r=0.336, P = 0.011); PRL and E2 (r=0.296, P = 0.037) and negative correlation between NO and E2 (r=-0.295, P = 0.038), NO and MDA (r=-0.302, P = 0.033) only in women with breast cancer. Conclusion: Breast cancer is associated with increased lipid peroxidation, nitric oxide and oxidative stress index which may be involved in the progression of the disease.

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