scholarly journals Serum vitamin d concentrations are associated with falling and cognitive function in older adults

2012 ◽  
Vol 16 (10) ◽  
pp. 898-901 ◽  
Author(s):  
Amie Peterson ◽  
N. Mattek ◽  
A. Clemons ◽  
G. L. Bowman ◽  
T. Buracchio ◽  
...  
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Cognitive Function ◽  
Serum Vitamin ◽  
Serum Vitamin D

Serum Vitamin D Concentrations and Cognitive Function in a Population-Based Study among Older Adults in South Germany

2015 ◽  
Vol 45 (4) ◽  
pp. 1119-1126 ◽  
Author(s):  
Gabriele Nagel ◽  
Florian Herbolsheimer ◽  
Matthias Riepe ◽  
Thorsten Nikolaus ◽  
Michael D. Denkinger ◽  
...  
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Cognitive Function ◽  
Serum Vitamin ◽  
Population Based ◽  
Population Based Study ◽  
Serum Vitamin D

IMPACT OF DIETARY FACTORS AND INFLAMMATION ON COGNITION AMONG OLDER ADULTS

2015 ◽  
pp. 1-7
Author(s):  
E.P. Handing ◽  
B.J. Small ◽  
S.L. Reynolds ◽  
N.B. Kumar
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Cognitive Function ◽  
Cognitive Performance ◽  
Serum Vitamin ◽  
Plasma Homocysteine ◽  
Dietary Factors ◽  
Serum Folate ◽  
Serum Vitamin D ◽  
Age Related

OBJECTIVE: This study examined the influence of age, nutrition (as measured through food diaries and serum/plasma biomarkers) and inflammatory markers on cognitive performance in adults 60 years of age and older. DESIGN: A cross-sectional population based study, data from the National Health and Nutrition Examination Survey (NHANES; 2001-2002 wave). PARTICIPANTS: This study included 1,048 adults who had valid dietary data, blood biomarkers, were 60 years or older, completed the cognitive test, and had complete demographic information. METHOD: A series of regression models were used to examine the relationship between cognitive function as measured by the Digit Symbol Substitution Task (DSST), dietary factors/biomarkers and inflammation. Mediation analyses were then utilized to examine whether individual nutrients accounted for the relationships between age and DSST performance. RESULTS: Dietary fat intake, serum vitamin E, serum folate, serum iron, plasma homocysteine, and serum vitamin D were significantly associated with better DSST performance. Elevated fibrinogen and C-reactive protein, were significantly associated with poorer cognitive function, but did not remain statistically significant after controlling for age, gender, education, ethnicity, income, and total calorie intake. Serum vitamin D and plasma homocysteine accounted for a portion of age-related variance in DSST. Specifically, higher levels of vitamin D were related to better DSST performance, while higher homocysteine resulted in poorer cognitive performance. CONCLUSION: Diet and nutrition are important modifiable factors that can influence health outcomes and may be beneficial to remediate age-related declines in cognition. Adequate nutrition may provide a primary preventive approach to healthy aging and maintenance of cognitive functioning in older adults.

Pysical Fitness And Serum Vitamin D And Cognitive Function In Older Adults

2016 ◽  
Vol 48 ◽  
pp. 317
Author(s):  
Sang-Koo Woo ◽  
Ji-Young Lee ◽  
Haeryun Hong ◽  
Hyun-Sik Kang
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Cognitive Function ◽  
Serum Vitamin ◽  
Serum Vitamin D

The association between serum vitamin d level and cognitive function in older adults: Cooper Center Longitudinal Study

2018 ◽  
Vol 113 ◽  
pp. 57-61 ◽  
Author(s):  
Andjelka Pavlovic ◽  
Katelyn Abel ◽  
Carolyn E. Barlow ◽  
Stephen W. Farrell ◽  
Myron Weiner ◽  
...  
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Longitudinal Study ◽  
Cognitive Function ◽  
Serum Vitamin ◽  
Serum Vitamin D

Higher Serum Vitamin D Concentration Is Associated with Better Balance in Older Adults with Supra-Optimal Vitamin D Status

2013 ◽  
Vol 61 (1) ◽  
pp. 163-165 ◽  
Author(s):  
Cedric Annweiler ◽  
Susan W. Muir ◽  
Shamis Nabeel ◽  
Karen Gopaul ◽  
Olivier Beauchet ◽  
...  
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Serum Vitamin ◽  
Vitamin D Status ◽  
Serum Vitamin D

scholarly journals Identification of Neuroprotective Factors Associated with Successful Ageing and Risk of Cognitive Impairment among Malaysia Older Adults

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Huijin Lau ◽  
Arimi Fitri Mat Ludin ◽  
Nor Fadilah Rajab ◽  
Suzana Shahar
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Cognitive Impairment ◽  
Telomere Length ◽  
Serum Vitamin ◽  
Dietary Vitamin ◽  
Ageing Population ◽  
Successful Ageing ◽  
Bdnf Level ◽  
Serum Vitamin D

The increase of ageing population has raised public attention on the concept of successful ageing. Studies have shown that vitamin D, telomere length, and brain-derived neurotrophic factor (BDNF) have been associated with cognitive function. Therefore, this study aimed to identify neuroprotective factors for cognitive decline in different ageing groups. A total of 300 older adults aged 60 years and above were recruited in this population based cross-sectional study. Participants were categorized into three groups: mild cognitive impairment (MCI) (n=100), usual ageing (UA) (n=100), and successful ageing (SA) (n=100). Dietary vitamin D intake was assessed through Diet History Questionnaire (DHQ). Out of the 300 participants, only 150 were subjected to fasting blood sample collection. These samples were used for serum vitamin D and plasma BDNF measurements. Whole blood telomere length was measured using RT-PCR method. The results show that the reduction of the risk of MCI was achieved by higher serum vitamin D level (OR: 0.96, 95% CI: 0.92–0.99, p<0.05), higher plasma BDNF level (OR: 0.51, 95% CI: 0.30–0.88,  p<0.05), and longer telomere (OR: 0.97, 95% CI: 0.95–0.99,  p<0.001). In conclusion, participants with higher vitamin D level, higher BDNF level, and longer telomere length were more likely to age successfully.

scholarly journals The Role of Inflammatory Diet and Vitamin D on the Link between Periodontitis and Cognitive Function: A Mediation Analysis in Older Adults

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 924
Author(s):  
João Botelho ◽  
Yago Leira ◽  
João Viana ◽  
Vanessa Machado ◽  
Patrícia Lyra ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cognitive Function ◽  
Cognitive Dysfunction ◽  
Mediation Analysis ◽  
Serum Vitamin ◽  
Cognitive Test ◽  
Digit Symbol Substitution Test ◽  
Cognitive Tests ◽  
Serum Vitamin D ◽  
Vitamin D Levels

Patients suffering from periodontitis are at a higher risk of developing cognitive dysfunction. However, the mediation effect of an inflammatory diet and serum vitamin D levels in this link is unclear. In total, 2062 participants aged 60 years or older with complete periodontal diagnosis and cognitive tests from the National Health and Nutrition Examination Survey (NHANES) 2011–2012 and 2013–2014 were enrolled. The Consortium to Establish a Registry for Alzheimer’s disease (CERAD) word learning subtest (WLT) and CERAD delayed recall test (DRT), the animal fluency test (AFT) and the digit symbol substitution test (DSST) was used. Dietary inflammatory index (DII) was computed via nutrition datasets. Mediation analysis tested the effects of DII and vitamin D levels in the association of mean probing depth (PD) and attachment loss (AL) in all four cognitive tests. Periodontitis patients obtained worse cognitive test scores than periodontally healthy individuals. DII was negatively associated with CERAD-WLT, CERAD-DRT, AFT and DSST, and was estimated to mediate between 9.2% and 36.4% of the total association between periodontitis with cognitive dysfunction (p < 0.05). Vitamin D showed a weak association between CERAD-DRT, AFT and DSST and was estimated to between 8.1% and 73.2% of the association between periodontitis and cognitive dysfunction (p < 0.05). The association between periodontitis and impaired cognitive function seems to be mediated both by a proinflammatory dietary load and vitamin D deficiency. Future studies should further explore these mediators in the periodontitis-cognitive decline link.

scholarly journals Vitamin D, Falls and Balance Capacity Impacts in Older Adults: Update

2021 ◽  
Vol 3 (4) ◽  
pp. 22-39
Author(s):  
Ray Marks
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Successful Aging ◽  
English Language ◽  
Balance Control ◽  
Serum Vitamin ◽  
Vitamin D Supplementation ◽  
Falls Prevention ◽  
Serum Vitamin D ◽  
Vitamin D Levels

Background Falls injuries continue to contribute to numerous premature deaths as well as high disability levels, and excess morbidity rates among older adults, worldwide. But can vitamin D account for excess falls injuries among older adults? This review specifically focuses on what is known about vitamin D in the context of postural stability or balance control, both fairly consistent independent predictors of falls among older adults. Methods and Procedures Drawn largely from a review of current relevant English language peer reviewed research publications published over the last 10 years detailing the relationship between vitamin D levels and balance control among the elderly, as this relates to falls injuries, evidence for any emerging consensus on this controversial topic was sought. Used to conduct the search were various key word combinations including: falls injuries and older adults, vitamin D or vitamin D deficiency and balance or postural control. The database used predominantly to provide input into this largely descriptive assessment and narrative overview was PUBMED. Results The prevailing data show falls injuries currently constitute a widespread costly major impediment to successful aging and longevity for many older adults, despite numerous efforts to prevent this disabling set of events over the past two to three decades. However, no consistent association appears to exist between the variables of vitamin D, falls, and balance attributes in the older population-despite years of research, regardless of study approach, and a strong rationale for hypothesizing a clinically meaningful relationship. Conclusion It is not possible to arrive at any universal recommendation concerning the value of vitamin D supplementation as regards its possible influence on balance capacity among older adults in the realm of falls prevention efforts, as has been frequently proposed. However, until more definitive research is conducted, there still appears sufficient justification for considering the screening of vulnerable aging adults for serum vitamin D levels, along with balance impairments, and intervening as required in the case of deficits in either or both of these possible falls determinants.

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