scholarly journals Maternal Serum Aneuploidy Screen and Adverse Pregnancy Outcomes

2016 ◽  
Vol 66 (S1) ◽  
pp. 141-148 ◽  
Author(s):  
Koumudi Godbole ◽  
Aparna Kulkarni ◽  
Asawari Kanade ◽  
Shilpa Kulkarni ◽  
Girish Godbole ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Maternal Serum ◽  
Adverse Pregnancy Outcomes ◽  
Adverse Pregnancy

Association between isolated abnormal levels of maternal serum unconjugated estriol in the second trimester and adverse pregnancy outcomes

2015 ◽  
Vol 29 (13) ◽  
pp. 2093-2097 ◽  
Author(s):  
Thaniyaporn Settiyanan ◽  
Chanane Wanapirak ◽  
Supatra Sirichotiyakul ◽  
Fuanglada Tongprasert ◽  
Kasemsri Srisupundit ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Maternal Serum ◽  
Adverse Pregnancy Outcomes ◽  
Second Trimester ◽  
Adverse Pregnancy ◽  
Unconjugated Estriol

scholarly journals Does the Predictive Value of Maternal Serum Alpha-Fetoprotein on Adverse Pregnancy Outcomes Vary by Race/Ethnicity?

2022 ◽  
Vol 226 (1) ◽  
pp. S185-S186
Author(s):  
Kaitlyn Kincaid ◽  
Yuanfan Ye ◽  
Rubymel J. Knupp ◽  
Jeff M. Szychowski ◽  
John Owen ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Predictive Value ◽  
Maternal Serum ◽  
Adverse Pregnancy Outcomes ◽  
Alpha Fetoprotein ◽  
Serum Alpha Fetoprotein ◽  
Race Ethnicity ◽  
Adverse Pregnancy

scholarly journals Mid-Trimester Maternal Serum AFP and hCG as Markers of Preterm and Term Adverse Pregnancy Outcomes

2015 ◽  
Vol 37 (2) ◽  
pp. 111-116 ◽  
Author(s):  
Sabrina Tancrède ◽  
Emmanuel Bujold ◽  
Yves Giguère ◽  
Marie-Hélène Renald ◽  
Joel Girouard ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Maternal Serum ◽  
Adverse Pregnancy Outcomes ◽  
Adverse Pregnancy

scholarly journals Pregnancy outcomes regarding maternal serum AFP value in second trimester screening

2017 ◽  
Vol 45 (7) ◽  
Author(s):  
Karolina Bartkute ◽  
Dalia Balsyte ◽  
Josef Wisser ◽  
Juozas Kurmanavicius
Keyword(s):  
Gestational Age ◽  
Pregnancy Outcomes ◽  
Maternal Serum ◽  
Adverse Pregnancy Outcomes ◽  
Fetal Malformation ◽  
Second Trimester ◽  
Second Trimester Screening ◽  
Newborn Weight ◽  
Fetal Malformations ◽  
Adverse Pregnancy

AbstractAim:The aim of this study was to evaluate the predictive value of α-fetoprotein in maternal serum (MS-AFP) as a marker for diverse pregnancy outcomes.Methods:The study was based on pregnancy and delivery data from 5520 women between 1999 and 2014 at University Hospital of Zurich (UHZ). Inclusion criteria: both MS-AFP and pregnancy outcome were known for the same pregnancy. Pregnancy outcomes and characteristics such as fetal malformation, intrauterine fetal death (IUFD) and intrauterine growth retardation as well as maternal age, weight before pregnancy, gestational age (GA) at delivery, newborn weight, length and head circumference were analyzed with respect to the MS-AFP value. MS-AFP value was categorized into three groups: elevated MS-AFP>2.5 multiples of the median (MoM), normal 0.5–2.49 MoM and decreased <0.5 MoM.Results:Newborn weight (g) and length (cm) were significantly lower in the elevated MS-AFP (P<0.001) group, and infants had 1 week lower GA at delivery (P<0.05). In the group of elevated MS-AFP (n=46), 26.1% of pregnancies were significantly related to adverse pregnancy outcomes, such as fetal malformations, fetuses small for gestational age (SGA) and IUFD. Adverse pregnancy outcomes of 5.6% were registered in the group of normal MS-AFP and 7.3% in the group of low MS-AFP (P<0.05).Conclusion:MS-AFP level in the second trimester is still an important indicator of fetal surface malformations; however, ultrasound still outweighs as a screening method. Nevertheless, pregnant women with elevated MS-AFP values and with no sonographically detected fetal malformations should additionally receive the third trimester ultrasound examination to exclude other possible complications of pregnancy.

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