scholarly journals Modeling hepatoblastoma development with human fetal liver organoids reveals YAP1 activation is sufficient for tumorigenesis

2021 ◽  
Author(s):  
Li Yang ◽  
Jin Chen ◽  
Jianqing Liang ◽  
Yufeng Zhang ◽  
Qingzhe Wang ◽  
...  
Keyword(s):  
Fetal Liver ◽  
Human Fetal Liver ◽  
Liver Organoids

Use of human fetal liver cells for treatment of patients with lower limb peripheral artery disease

2014 ◽  
Vol 2 (1) ◽  
pp. 10-13
Author(s):  
R. Salyutin ◽  
D. Dombrowski ◽  
M. Komarov ◽  
N. Sokolov ◽  
S. Palyanitsya ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Lower Limb ◽  
Fetal Liver ◽  
Life Quality ◽  
Liver Cells ◽  
Surgical Reconstruction ◽  
Clinical Effects ◽  
Doppler Flowmetry ◽  
Human Fetal Liver ◽  
Fetal Liver Cells

In the group of patients (n = 21, mean age 54 ± 5.8 years) with chronic lower limb ischemia stage IIB who were non-liable for reconstructiverestoration surgery, we have established positive clinical effects of local transplantation of human fetal liver progenitor cells. Complex examination following 1, 3, 6 and 12 months after transplantation included duplex scanning of limb arteries, x-ray contrast arteriography and laser Doppler flowmetry as well as measuring pain-free walking and evaluating life quality based on individual questionnaire data.Owing to the transplant “Cryopreserved human fetal liver progenitor cells” the patients demonstrated stable increase of life quality index and pain-free walking as well as improvement of general health allowing assign them to the group of patients with lower ischemia stage,  quicker social rehabilitation and lesser risk of disabling surgery (р < 0.05). Also, there were observations of improved microcirculation in the ischemic extremities owing to activation of endothelium-independent mechanisms of vasodilatation, reduced myotonus and neurotonus of the pre-capillaries and improved endothelium-dependent influence on the microhaemodynamic and, hence, an increased reserve capillary blood flow (p < 0.05).Analysis of the obtained results indicates prospects and effectiveness of using fetal liver cells transplantation in the patients who are not liable for surgical reconstruction of the vascular bed.

scholarly journals Hepatitis C virus infection induces endoplasmic reticulum stress and apoptosis in human fetal liver stem cells

2019 ◽  
Vol 248 (2) ◽  
pp. 155-163 ◽  
Author(s):  
Xuan Guo ◽  
Wei‐Li Liu ◽  
Dong Yang ◽  
Zhi‐Qiang Shen ◽  
Zhi‐Gang Qiu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Endoplasmic Reticulum ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Endoplasmic Reticulum Stress ◽  
Fetal Liver ◽  
Hepatitis C Virus Infection ◽  
Human Fetal Liver ◽  
Liver Stem Cells

scholarly journals Comparison of Basal Gene Expression and Induction of CYP3As in HepG2 and Human Fetal Liver Cells

2007 ◽  
Vol 30 (11) ◽  
pp. 2091-2097 ◽  
Author(s):  
Masataka Maruyama ◽  
Tamihide Matsunaga ◽  
Eri Harada ◽  
Shigeru Ohmori
Keyword(s):  
Gene Expression ◽  
Fetal Liver ◽  
Liver Cells ◽  
Human Fetal Liver ◽  
Fetal Liver Cells ◽  
Human Fetal Liver Cells

Biotransformation of benzo[a]pyrene and 7-ethoxyresorufin and heme-staining proteins in microsomes from human fetal liver and placenta

1983 ◽  
Vol 32 (10) ◽  
pp. 1547-1552 ◽  
Author(s):  
Agneta Blanck ◽  
Anders Rane ◽  
Rune Toftgård ◽  
Jan-Åke Gustafsson
Keyword(s):  
Fetal Liver ◽  
Human Fetal Liver

Screening of binding proteins that interact with human Salvador 1 in a human fetal liver cDNA library by the yeast two-hybrid system

2012 ◽  
Vol 39 (8) ◽  
pp. 8225-8230 ◽  
Author(s):  
Xiaolan Li ◽  
Xuelai Luo ◽  
Zhaoming Li ◽  
Guihua Wang ◽  
Hui Xiao ◽  
...  
Keyword(s):  
Cdna Library ◽  
Hybrid System ◽  
Binding Proteins ◽  
Fetal Liver ◽  
Yeast Two Hybrid ◽  
Human Fetal Liver ◽  
Yeast Two Hybrid System ◽  
Liver Cdna Library ◽  
Two Hybrid
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