scholarly journals A Prospective Longitudinal Study on the Relationship Between Glucose Fluctuation and Cognitive Function in Type 2 Diabetes: PROPOSAL Study Protocol

2020 ◽  
Vol 11 (11) ◽  
pp. 2729-2737
Author(s):  
Masaki Matsubara ◽  
Hisashi Makino ◽  
Kazuo Washida ◽  
Miki Matsuo ◽  
Ryo Koezuka ◽  
...  
2018 ◽  
Vol 8 (4) ◽  
pp. 333-344 ◽  
Author(s):  
Henriette Bergstrøm ◽  
David P. Farrington

Purpose The purpose of this paper is to investigate the relationship between resting heart rate (RHR) and psychopathy. The literature on heart rate vs criminality (including violence) is quite clear; low RHR is associated with engaging in violent and criminal behavior. However, results are not as consistent for psychopathy. Design/methodology/approach This paper analyzes heart rate measured at ages 18 and 48, and psychopathy at age 48, in the Cambridge Study in Delinquent Development (CSDD). The CSDD is a prospective longitudinal study that has followed 411 boys from childhood to middle age, and measured social and biological factors of interest to the field of criminal psychology. Findings Interestingly, it was only heart rate at age 18 that was negatively and significantly related to psychopathy at age 48. No trends or relationships were found between heart rate at age 48 and psychopathy at age 48. The findings do, however, indicate that low heart rate at age 18 predicts psychopathy at age 48, and the strongest negative relationships are found between low heart rate (beats per minute) and impulsive and antisocial psychopathic symptoms. Originality/value This is the first ever longitudinal study showing that low RHR predicts later psychopathy. Suggestions for future research are outlined.


2020 ◽  
Vol 9 (11) ◽  
pp. 3735
Author(s):  
Sook Ling Leong ◽  
Ian H. Robertson ◽  
Brian Lawlor ◽  
Sven Vanneste

Epidemiological studies have produced conflicting results regarding the associations between the use of different hypertensive drugs and cognition. Data from the Irish Longitudinal Study on Ageing (TILDA), a nationwide prospective longitudinal study of adults aged 50 or more years, was used to explore the associations between hypertensive status, categories of antihypertensive and cognitive function controlling for age, education, and other demographic and lifestyle factors. The study sample included 8173 participants. ANCOVAs and multivariate regressions were used to assess the cross-sectional and longitudinal associations between cognitive function and hypertension status and the different categories of hypertensive medication. Hypertension was not associated with decline in global cognitive and executive functions and were fully explained by age and education. Different hypertensive medications were not associated with cognitive function. Consistent with previous studies, changes in cognition can largely be explained by age and education. The use of antihypertensive medications is neither harmful nor protective for cognition.


Pain ◽  
2012 ◽  
Vol 153 (1) ◽  
pp. 113-119 ◽  
Author(s):  
Steven J. Kamper ◽  
Christopher G. Maher ◽  
Luciola da C. Menezes Costa ◽  
James H. McAuley ◽  
Julia M. Hush ◽  
...  

2008 ◽  
Vol 36 (6) ◽  
pp. 1392-1398 ◽  
Author(s):  
I Capoglu ◽  
A Ozkan ◽  
B Ozkan ◽  
Z Umudum

The aim of this prospective, longitudinal study was to investigate, over a period of 12 months, the effects of metabolic control on bone turnover markers in patients with type 2 diabetes mellitus. The study included 17 male and 18 female patients with type 2 diabetes, aged 37 − 66 years. Mean follow-up period was 12 ± 1.2 months. Mean glycosylated haemoglobin (HbA1C) levels were 10.6% ± 1.6% at the start of the study and decreased to 7.7% ± 1.0% by the end of the study. Levels of the bone resorption markers, urinary deoxypyridinoline and N-telopeptide, were 28.6 ± 11.6 nmol/mmol creatinine and 93.6 ± 13.7 nmol bone collagen equivalents [BCE]/mmol creatinine, respectively, at the start of the study, and decreased significantly to 17.9 ± 7.1 nmol/mmol creatinine and 67.8 ± 12.8 nmol BCE/mmol creatinine, respectively, by the end of the study. Bone formation parameters also significantly decreased in parallel with HbA1c levels over the study period. It is concluded that effective management of metabolic disorder in patients with type 2 diabetes plays an important contribution to bone turnover improvement.


2018 ◽  
Vol 56 (1) ◽  
pp. 121-122
Author(s):  
Sunee Saetung ◽  
Hataikarn Nimitphong ◽  
Nantaporn Siwasaranond ◽  
Rungtip Sumritsopak ◽  
Panitha Jindahra ◽  
...  

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