Laparoscopic versus open distal gastrectomy for locally advanced gastric cancer: a case–control study

2011 ◽  
Vol 63 (1) ◽  
pp. 17-23 ◽  
Author(s):  
Marco Scatizzi ◽  
Katrin C. Kröning ◽  
Elisa Lenzi ◽  
Luca Moraldi ◽  
Stefano Cantafio ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Case Control Study ◽  
Distal Gastrectomy ◽  
Locally Advanced ◽  
Case Control ◽  
Open Distal Gastrectomy ◽  
Locally Advanced Gastric Cancer ◽  
Control Study

scholarly journals Correction to: Prophylactic HIPEC with radical D2 gastrectomy improves survival and peritoneal recurrence rates for locally advanced gastric cancer: personal experience from a randomized case control study

BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Maneesh Kumarsing Beeharry ◽  
Zheng-Lun Zhu ◽  
Wen-Tao Liu ◽  
Xue-Xin Yao ◽  
Min Yan ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Personal Experience ◽  
Case Control Study ◽  
Locally Advanced ◽  
Case Control ◽  
Recurrence Rates ◽  
D2 Gastrectomy ◽  
Locally Advanced Gastric Cancer ◽  
Control Study

Following publication of the original article [1], the authors reported the following errors/updates.

A Case–Control Study of Laparoscopy-Assisted and Open Distal Gastrectomy for Advanced Gastric Cancer

2010 ◽  
Vol 15 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Jianbo Shuang ◽  
Shengbin Qi ◽  
Jianyong Zheng ◽  
Qinchuan Zhao ◽  
Jipeng Li ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Case Control Study ◽  
Distal Gastrectomy ◽  
Case Control ◽  
Open Distal Gastrectomy ◽  
Control Study

scholarly journals Prophylactic HIPEC with radical D2 gastrectomy improves survival and peritoneal recurrence rates for locally advanced gastric cancer: personal experience from a randomized case control study

BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Maneesh Kumarsing Beeharry ◽  
Zheng-Lun Zhu ◽  
Wen-Tao Liu ◽  
Xue-Xin Yao ◽  
Min Yan ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Curative Resection ◽  
Case Control Study ◽  
Locally Advanced ◽  
Case Control ◽  
Peritoneal Recurrence ◽  
Control Group ◽  
Recurrence Rates ◽  
Locally Advanced Gastric Cancer ◽  
Control Study

Abstract Background To investigate the implications of prophylactic intraoperative Hyperthermic Intraperitoneal Chemotherapy (HIPEC) with D2 radical gastrectomy for locally advanced Gastric Cancer (AGC) in a randomized case control study. Method Eighty consecutive patients with locally AGC were randomly separated into 2 groups: HIPEC group (Curative Resection + intraoperative HIPEC with cisplatin 50 mg/m2 at 42.0 ± 1.0 °C for 60 min) and Control group (Curative Resection only). Intraoperative and post-operative events, clinical recovery, morbidity and the disease-free survival (DFS) rates were closely monitored. Results Faster recovery of bowel function (43 ± 5 h vs 68 ± 7, P < 0.05) and shorter postoperative stay (8d vs 14d, P < 0.05) were noted in the HIPEC group. Among the 40 HIPEC group patients, the highest intracranial temperature recorded during the procedure was 38.2 °C but the patient made an eventless recovery. Mild renal dysfunction, hyperbilirubinemia and mild liver dysfunction were recorded in the HIPEC group but their incidences were found to be statistically insignificant when compared with the control group (P > 0.05). The 3 year DFS rate analysis showed that the prophylactic HIPEC group had a higher DFS rate (93% vs 65%, P = 0.0054). The peritoneal recurrence rate was lower in the HIPEC group (3% vs 23%, P < 0.05). Conclusion Prophylactic HIPEC with radical D2 Gastrectomy improves survival and peritoneal recurrence rates for AGC with favorable post-operative recovery at low and acceptable morbidity.

scholarly journals P-263 Laparoscopic versus open distal gastrectomy for gastric cancer: a single-center case-control study

2016 ◽  
Vol 27 ◽  
pp. ii76
Author(s):  
B. Castro ◽  
M. Aral ◽  
A. Fareleira ◽  
J. Costa-Maia ◽  
H. Santos-Sousa
Keyword(s):  
Gastric Cancer ◽  
Case Control Study ◽  
Distal Gastrectomy ◽  
Case Control ◽  
Open Distal Gastrectomy ◽  
Single Center ◽  
Control Study

Long-Term Outcomes of Laparoscopic Distal Gastrectomy for Locally Advanced Gastric Cancer: The KLASS-02-RCT Randomized Clinical Trial

2020 ◽  
Vol 38 (28) ◽  
pp. 3304-3313 ◽  
Author(s):  
Woo Jin Hyung ◽  
Han-Kwang Yang ◽  
Young-Kyu Park ◽  
Hyuk-Joon Lee ◽  
Ji Yeong An ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Open Surgery ◽  
Distal Gastrectomy ◽  
Locally Advanced ◽  
Laparoscopic Distal Gastrectomy ◽  
D2 Lymphadenectomy ◽  
Relapse Free Survival ◽  
Free Survival ◽  
Locally Advanced Gastric Cancer

PURPOSE It is unclear whether laparoscopic distal gastrectomy for locally advanced gastric cancer is oncologically equivalent to open distal gastrectomy. The noninferiority of laparoscopic subtotal gastrectomy with D2 lymphadenectomy for locally advanced gastric cancer compared with open surgery in terms of 3-year relapse-free survival rate was evaluated. PATIENTS AND METHODS A phase III, open-label, randomized controlled trial was conducted for patients with histologically proven locally advanced gastric adenocarcinoma suitable for distal subtotal gastrectomy. The primary end point was the 3-year relapse-free survival rate; the upper limit of the hazard ratio (HR) for noninferiority was 1.43 between the laparoscopic and open distal gastrectomy groups. RESULTS From November 2011 to April 2015, 1,050 patients were randomly assigned to laparoscopy (n = 524) or open surgery (n = 526). After exclusions, 492 patients underwent laparoscopic surgery and 482 underwent open surgery and were included in the analysis. The laparoscopy group, compared with the open surgery group, suffered fewer early complications (15.7% v 23.4%, respectively; P = .0027) and late complications (4.7% v 9.5%, respectively; P = .0038), particularly intestinal obstruction (2.0% v 4.4%, respectively; P = .0447). The 3-year relapse-free survival rate was 80.3% (95% CI, 76.0% to 85.0%) for the laparoscopy group and 81.3% (95% CI, 77.0% to 85.0%; log-rank P = .726) for the open group. Cox regression analysis after stratification by the surgeon revealed an HR of 1.035 (95% CI, 0.762 to 1.406; log-rank P = .827; P for noninferiority = .039). When stratified by pathologic stage, the HR was 1.020 (95% CI, 0.751 to 1.385; log-rank P = .900; P for noninferiority = .030). CONCLUSION Laparoscopic distal gastrectomy with D2 lymphadenectomy was comparable to open surgery in terms of relapse-free survival for patients with locally advanced gastric cancer. Laparoscopic distal gastrectomy with D2 lymphadenectomy could be a potential standard treatment option for locally advanced gastric cancer.

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