scholarly journals Covid-19 post-infectious acute transverse myelitis responsive to corticosteroid therapy: report of two clinical cases

Author(s):  
Thaís de Maria Frota Vasconcelos ◽  
Danilo Nunes Oliveira ◽  
Glauber de Menezes Ferreira ◽  
Fabrícia Carneiro Torres ◽  
José Daniel Vieira de Castro ◽  
...  
2016 ◽  
Vol 13 (2) ◽  
pp. 89-91 ◽  
Author(s):  
Avinash Chandra ◽  
Reema Rajbhandari ◽  
Samir Acharya ◽  
Priya Gurung ◽  
Basant Pant

Acute transverse myelitis is a focal infl ammatory disorder of the spinal cord. One of the main etiologic factors include, multiple sclerosis, post-infectious and post-traumatic events although autoimmune phenomenon is the most common cause. Transverse Myelitis (TM) due to etiology other than Multiple Sclerosis has shown spinal cord involvement of two or more segments. Annually millions of active immunization with vaccines is carried out globally with few transverse myelitis caused because of the adverse reactions due to these vaccinations. In order to improve accuracy of reporting, research and diagnosis, the Transverse Myelitis Consortium Working Group (TMCWG) have produced criteria for the diagnosis of ATM. Here we report a case of TM in adult, diagnosed as TM consistent with the TMCWG criteria and probably this is the first ever been reported case from Nepal. Nepal Journal of Neuroscience. Vol. 13, No. 2, 2016, Page: 89-91 


Author(s):  
Hamze Shahali ◽  
Ali Ghasemi ◽  
Ramin Hamidi Farahani ◽  
Amir Nezami Asl ◽  
Ebrahim Hazrati

Author(s):  
Jelte Helfferich ◽  
Arlette L. Bruijstens ◽  
Yu Yi M. Wong ◽  
E. Danielle van Pelt ◽  
Maartje Boon ◽  
...  

2017 ◽  
Vol 24 (13) ◽  
pp. 1743-1752 ◽  
Author(s):  
Matteo Gastaldi ◽  
Enrico Marchioni ◽  
Paola Banfi ◽  
Valeria Mariani ◽  
Laura Di Lodovico ◽  
...  

Background: Transverse myelitis (TM) is an inflammatory disorder that can be idiopathic or associated with central nervous system autoimmune/dysimmune inflammatory diseases, connective tissue autoimmune diseases, or post-infectious neurological syndromes. Prognosis of initial TM presentations is uncertain. Objective: To identify outcome predictors in TM. Methods: Retrospective study on isolated TM at onset. Scores ⩾3 on the modified Rankin scale (mRS) marked high disability. Results: A total of 159 patients were identified. TM was classified as follows: idiopathic (I-TM, n = 53), post-infectious (PI-TM, n = 48), associated with multiple sclerosis (MS-TM, n = 51), or neuromyelitis optica spectrum disorders/connective tissue autoimmune diseases/neurosarcoidosis ( n = 7). At follow-up (median, 55 months; interquartile range, 32–80), 42 patients were severely disabled, and patients with I-TM or PI-TM showed the worst outcomes. Predictors of disability were infectious antecedents, sphincter and pyramidal symptoms, high mRS scores, blood–cerebrospinal fluid barrier damage, lumbar magnetic resonance imaging (MRI) lesions on univariate analysis, and older age (odds ratio (OR), 1.1; 95% confidence interval (CI), 1.0–1.1), overt/subclinical involvement of the peripheral nervous system (PNS) (OR, 9.4; 95% CI, 2.2–41.0), complete TM (OR, 10.8; 95% CI, 3.4–34.5) on multivariate analysis. Conclusion: Our findings help define prognosis and therapies in TM at onset. Infectious antecedents and PNS involvement associate with severe prognosis. Nerve conduction studies and lumbar MRI could improve the prognostic assessment of this condition.


2009 ◽  
Vol 24 (4) ◽  
pp. 466-471 ◽  
Author(s):  
Veena Kalra ◽  
Suvasini Sharma ◽  
Jitendra Sahu ◽  
Naveen Sankhyan ◽  
Rama Chaudhry ◽  
...  

PEDIATRICS ◽  
1978 ◽  
Vol 62 (2) ◽  
pp. 202-204
Author(s):  
John T. McCarthy ◽  
Jules Amer

Although the complications and sequelae of varicella are rare, they can cause significant mortality and morbidity in both the normal and compromised patient. Eight cases of "pure" acute transverse myelitis (ATM) following varicella have previously been reported in the literature. We report the ninth case of postvaricella ATM in a 9-year-old girl. Her course was characterized by paraplegia, sensory Loss, hvperesthesia, and incontinence of urine and feces. All patients, except ours, recovered fully from ATM.


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