Acute hypoglycemic and antihyperglycemic effects of ten Sri Lankan medicinal plant extracts in healthy and streptozotocin induced diabetic rats

2014 ◽  
Vol 35 (3) ◽  
pp. 177-183 ◽  
Author(s):  
Anoja Priyadarshani Attanayake ◽  
Kamani Ayoma Perera Wijewardena Jayatilaka ◽  
Chitra Pathirana ◽  
Lakmini Kumari Boralugoda Mudduwa
Keyword(s):  
Medicinal Plant ◽  
Plant Extracts ◽  
Diabetic Rats ◽  
Sri Lankan ◽  
Medicinal Plant Extracts

scholarly journals Study of antihyperglycaemic activity of medicinal plant extracts in alloxan induced diabetic rats

2013 ◽  
Vol 32 (4) ◽  
pp. 193 ◽  
Author(s):  
AnojaP Attanayake ◽  
KamaniA. P. W. Jayatilaka ◽  
Chitra Pathirana ◽  
LakminiK. B. Mudduwa
Keyword(s):  
Medicinal Plant ◽  
Plant Extracts ◽  
Diabetic Rats ◽  
Medicinal Plant Extracts

scholarly journals Acetylcholinesterase Inhibitory Activity and Antioxidant Activity of Selected Medicinal Plant Extracts Used Against Cognitive Dysfunction and Memory Loss in Sri Lankan Traditional Medicine

2018 ◽  
Vol 6 (5) ◽  
pp. 16-25
Author(s):  
Anoja Priyadarshani Attanayake ◽  
Kamani Ayoma Perera Wijewardana Jayatilaka
Keyword(s):  
Antioxidant Activity ◽  
Medicinal Plant ◽  
Plant Extracts ◽  
Inhibitory Activity ◽  
Ricinus Communis ◽  
Centella Asiatica ◽  
Sri Lankan ◽  
Medicinal Plant Extracts ◽  
Ache Inhibitory Activity ◽  
Alzheimer’S Diseases

The objectives of the study were to determine the acetylcholinesterase (AChE) inhibitory activity and antioxidant activity in the selected Sri Lankan medicinal plants. AChE inhibitory activity of the selected medicinal plant extracts was determined using the Ellman’s method. The antioxidant activities were determined by four in vitro methods namely DPPH assay, FRAP assay, NO assay and TBA acid method.  The contents of total polyphenols and flavonoids were determined quantitatively.Out of the ten selected medicinal plant extracts Abrus precatorius, Centella asiatica, Strychnos nux-vomica and Ricinus communis showed IC50 values < 200 µg/mL for AChE inhibitory activity. A high antioxidant activity was shown in the extracts of Cardiosprmum halicacabum, Centella asiatica and  Ricinus communis in  the four selected antioxidant assays.  The total polyphenol content and total flavonoid content was in the range of 0.55-7.30 mg/g DW and 19.08±0.29-1283.08± 0.09 µg/gDW. The extracts of A. precatorius, C. asiatica, S. nux-vomica and R. communis are deserved to be as potent sources of AChE inhibitors as well as natural antioxidants. Considering the complex multifactorial etiology of Alzheimer's diseases, these plant extracts would be apt candidates for the development of novel pharmaceutical agents in the management of Alzheimer's diseases.  

scholarly journals Protective effects of three selected standardized medicinal plant extracts used in Sri Lankan traditional medicine in adriamycin induced nephrotoxic Wistar rats

2020 ◽  
Vol 259 ◽  
pp. 112933
Author(s):  
Sachinthi S. Amarasiri ◽  
Anoja P. Attanayake ◽  
Liyanagae D.A.M. Arawwawala ◽  
Kamani A.P.W. Jayatilaka ◽  
Lakmini K.B. Mudduwa
Keyword(s):  
Medicinal Plant ◽  
Traditional Medicine ◽  
Plant Extracts ◽  
Wistar Rats ◽  
Sri Lankan ◽  
Protective Effects ◽  
Medicinal Plant Extracts

Screening of 50 medicinal plant extracts for quercetin-3-rutinoside

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
E Sofic ◽  
M Salihovic ◽  
S Huseinovic ◽  
S Cavar ◽  
A Copra-Janicijevic ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Plant Extracts ◽  
Medicinal Plant Extracts

Screening of Venezuelan medicinal plant extracts for cytostatic and cytotoxic activity against tumour cell lines

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
P Taylor ◽  
M Arsenak ◽  
MJ Abad ◽  
Á Fernández ◽  
R Gonto ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Plant Extracts ◽  
Tumour Cell ◽  
Medicinal Plant Extracts ◽  
Tumour Cell Lines
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