scholarly journals Human Dental Pulp Stem Cells (DPSCs) Therapy in Rescuing Photoreceptors and Establishing a Sodium Iodate-Induced Retinal Degeneration Rat Model

2021 ◽  
Author(s):  
Chenshen Lam ◽  
Hiba Amer Alsaeedi ◽  
Avin Ee-Hwan Koh ◽  
Mohd Hairul Nizam Harun ◽  
Angela Ng Min Hwei ◽  
...  
Keyword(s):  
Stem Cells ◽  
Retinal Degeneration ◽  
Rat Model ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Sodium Iodate ◽  
Human Dental Pulp

scholarly journals Dental pulp stem cells therapy overcome photoreceptor cell death and protects the retina in a rat model of sodium iodate-induced retinal degeneration

2019 ◽  
Vol 198 ◽  
pp. 111561 ◽  
Author(s):  
Hiba Amer Alsaeedi ◽  
Avin Ee-Hwan Koh ◽  
Chenshen Lam ◽  
Munirah Binti Abd Rashid ◽  
Mohd Hairul Nizam Harun ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cell Death ◽  
Retinal Degeneration ◽  
Rat Model ◽  
Dental Pulp ◽  
Photoreceptor Cell ◽  
Dental Pulp Stem Cells ◽  
Sodium Iodate ◽  
Stem Cells Therapy

scholarly journals Modulation of Cell Death and Promotion of Chondrogenic Differentiation by Fas/FasL in Human Dental Pulp Stem Cells (hDPSCs)

2020 ◽  
Vol 8 ◽  
Author(s):  
Alessandra Pisciotta ◽  
Giulia Bertani ◽  
Laura Bertoni ◽  
Rosanna Di Tinco ◽  
Sara De Biasi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cell Death ◽  
Dental Pulp ◽  
Chondrogenic Differentiation ◽  
Dental Pulp Stem Cells ◽  
Human Dental Pulp

Chrysin induces osteogenic differentiation of human dental pulp stem cells

2021 ◽  
Vol 400 (2) ◽  
pp. 112466
Author(s):  
J.F. Huo ◽  
M.L. Zhang ◽  
X.X. Wang ◽  
D.H. Zou
Keyword(s):  
Stem Cells ◽  
Osteogenic Differentiation ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Human Dental Pulp

scholarly journals Methylglyoxal-Dependent Glycative Stress Is Prevented by the Natural Antioxidant Oleuropein in Human Dental Pulp Stem Cells through Nrf2/Glo1 Pathway

Antioxidants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 716
Author(s):  
Simona Delle Delle Monache ◽  
Fanny Pulcini ◽  
Roberta Frosini ◽  
Vincenzo Mattei ◽  
Vincenzo Nicola Talesa ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Great Promise ◽  
Oral Diseases ◽  
Bioactive Component ◽  
Glycation End Products ◽  
Abnormal Accumulation ◽  
Synthetic Agents ◽  
Human Dental Pulp

Methylglyoxal (MG) is a potent precursor of glycative stress (abnormal accumulation of advanced glycation end products, AGEs), a relevant condition underpinning the etiology of several diseases, including those of the oral cave. At present, synthetic agents able to trap MG are known; however, they have never been approved for clinical use because of their severe side effects. Hence, the search of bioactive natural scavengers remains a sector of strong research interest. Here, we investigated whether and how oleuropein (OP), the major bioactive component of olive leaf, was able to prevent MG-dependent glycative stress in human dental pulp stem cells (DPSCs). The cells were exposed to OP at 50 µM for 24 h prior to the administration of MG at 300 µM for additional 24 h. We found that OP prevented MG-induced glycative stress and DPSCs impairment by restoring the activity of Glyoxalase 1 (Glo1), the major detoxifying enzyme of MG, in a mechanism involving the redox-sensitive transcription factor Nrf2. Our results suggest that OP holds great promise for the development of preventive strategies for MG-derived AGEs-associated oral diseases and open new paths in research concerning additional studies on the protective potential of this secoiridoid.

scholarly journals Cdc42 is essential for the polarized movement and adhesion of human dental pulp stem cells

2018 ◽  
Vol 85 ◽  
pp. 104-112 ◽  
Author(s):  
Mingwei Li ◽  
Liang Ma ◽  
Bing Song ◽  
Dingyi Yu ◽  
Min Xiao ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Human Dental Pulp

scholarly journals Dynamic hydrostatic pressure promotes differentiation of human dental pulp stem cells

2009 ◽  
Vol 386 (4) ◽  
pp. 661-665 ◽  
Author(s):  
V. Yu ◽  
M. Damek-Poprawa ◽  
S.B. Nicoll ◽  
S.O. Akintoye
Keyword(s):  
Stem Cells ◽  
Hydrostatic Pressure ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Human Dental Pulp
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