Rate and Outcome of Acute Kidney Injury Following Hip Fracture Surgery in Diabetic Older Patients Treated with Renin–Angiotensin–Aldosterone Antagonists

Drugs & Aging ◽  
2019 ◽  
Vol 36 (7) ◽  
pp. 667-674 ◽  
Author(s):  
Tal Frenkel Rutenberg ◽  
Abdelazeez Bdeir ◽  
Benaya Rozen-Zvi ◽  
Yoav Rosenthal ◽  
Steven Velkes ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Hip Fracture ◽  
Older Patients ◽  
Kidney Injury ◽  
Aldosterone Antagonists ◽  
Renin Angiotensin ◽  
Hip Fracture Surgery ◽  
Fracture Surgery

scholarly journals Predictors of Acute Kidney Injury After Hip Fracture in Older Adults

2020 ◽  
Vol 11 ◽  
pp. 215145932092008 ◽  
Author(s):  
Julie Braüner Christensen ◽  
Martin Aasbrenn ◽  
Luana Sandoval Castillo ◽  
Anette Ekmann ◽  
Thomas Giver Jensen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Hip Fracture ◽  
Blood Transfusion ◽  
Multivariable Analysis ◽  
Kidney Injury ◽  
C Reactive Protein ◽  
Hip Fracture Surgery ◽  
Reactive Protein ◽  
Fracture Surgery

Introduction: This study aimed to investigate the prevalence of acute kidney injury (AKI) following hip fracture surgery in geriatric patients and to identify predictors for development of AKI with a focus on possible preventable risk factors. Methods: In this retrospective cohort study, we reviewed electronic medical records of all patients above 65 years of age who underwent hip fracture surgery at Copenhagen University Hospital, Bispebjerg, Denmark, in 2018. Acute kidney injury was assessed according to the Kidney Disease Improving Global Outcomes guidelines. Multivariate logistic regression analyses were used to identify independent risk factors for AKI. Results: Postoperative AKI developed in 28.4% of the included patients (85/299). Acute kidney injury was associated with increased length of admission (11.3 vs 8.7 days, P < .001) and 30-day mortality (18/85 vs 16/214, P = .001). In multivariable analysis, higher age (odds ratio [OR]: 1.05, 95% confidence interval [CI]: 1.01-1.08, P = .004), heart disease (OR: 1.78, 95% CI: 1.01-3.11, P = .045), and postoperative blood transfusion (OR: 1.84, 95% CI: 1.01-3.36, P = .048) were associated with AKI. Moreover, a higher postoperative C-reactive protein (199.0 ± 99.9 in patients with AKI, 161.3 ± 75.2 in patients without AKI) and lower postoperative diastolic blood pressure were observed in patients developing AKI. Discussion and Conclusion: Acute kidney injury was common following hip fracture surgery and associated with longer admissions and increased mortality. Patients developing AKI were older and showed several postoperative similarities, including higher C-reactive protein, lower postoperative diastolic pressure, and the need for blood transfusion.

scholarly journals FO069RISK AND PROGNOSIS OF ACUTE KIDNEY INJURY IN BISPHOSPHONATE USERS UNDERGOING HIP FRACTURE SURGERY

2018 ◽  
Vol 33 (suppl_1) ◽  
pp. i48-i49
Author(s):  
Christian Christiansen ◽  
Nisha Shetty ◽  
Uffe Heide-Jørgensen ◽  
Henrik Toft Sørensen ◽  
Vera Ehrenstein ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Hip Fracture ◽  
Kidney Injury ◽  
Hip Fracture Surgery ◽  
Fracture Surgery

Acute kidney injury after hip fracture surgery in patients over 80 years of age

2021 ◽  
Author(s):  
Anil Agar ◽  
Deniz Gulabi ◽  
Adem Sahin ◽  
Orhan Gunes ◽  
Cafer Ozgur Hancerli ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Hip Fracture ◽  
Kidney Injury ◽  
Hip Fracture Surgery ◽  
Fracture Surgery

scholarly journals Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery

PLoS ONE ◽  
2017 ◽  
Vol 12 (4) ◽  
pp. e0176259 ◽  
Author(s):  
Seong Eun Hong ◽  
Tae-Young Kim ◽  
Je-Hyun Yoo ◽  
Jwa-Kyung Kim ◽  
Sung Gyun Kim ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Hip Fracture ◽  
Elderly Patients ◽  
Kidney Injury ◽  
Hip Fracture Surgery ◽  
Fracture Surgery ◽  
Long Term Mortality

scholarly journals A Meta-Analysis of Acute Kidney Injury in Patients Undergoing Hip Fracture Surgery: Prevalence and Risk Factors

2020 ◽  
Author(s):  
Yan-Li Zhang ◽  
Yan-Chuang Pu ◽  
Jin Wang ◽  
Zi-Cai Li ◽  
Hu-Lin Wang
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Hip Fracture ◽  
Serum Albumin ◽  
Meta Analysis ◽  
Kidney Injury ◽  
Hip Fracture Surgery ◽  
Pooled Prevalence ◽  
Postoperative Serum ◽  
Fracture Surgery

Abstract Objective: Acute kidney injury(AKI) was a frequent complication following hip fracture surgery, but recent studies reported inconsistent findings. The purpose of our study was to systematically clarify the prevalence and risk factors of AKI after hip fracture surgery. Methods: Pubmed, Embase, and Web of Science were searched from the inception to March 2020 to identify observational studies investigating the prevalence and risk factors of AKI in patients undergoing hip fracture surgery. Pooled prevalence and odds ratios(ORs) with 95% confidence intervals(CIs) were estimated using random-effect model. Publication bias was evaluated with a funnel plot and statistical test. All the statistical analyses were performed using STATA version 12.0. Results: A total of 11 studies with 16,421 patients were included in the current meta-analysis. The pooled prevalence of AKI in patients undergoing hip fracture surgery was 17%(95%CI, 14%-21%). Postoperative serum albumin(OR 1.80; 95%CI, 1.38–2.36) was a significant predictor for AKI. Age(OR 1.01; 95%CI, 0.95–1.07) and ACE inhibitors(OR 1.38; 95%CI, 0.92–2.07) were also associated with increased risk of AKI, but the results were not statistically significant. No significant publication bias was identified through statistical tests(Egger’s test, p = 0.258 and Begg’s test, p = 0.087). Conclusions: The pooled AKI following hip fracture surgery was approximately 17%. Postoperative serum albumin was a potential significant risk factor for AKI.

scholarly journals Risk Factors for Acute Kidney Injury After Hip Fracture Surgery in the Elderly Individuals

2012 ◽  
Vol 3 (4) ◽  
pp. 150-156 ◽  
Author(s):  
Cagatay Ulucay ◽  
Zehra Eren ◽  
Elif Cigdem Kaspar ◽  
Turhan Ozler ◽  
Korcan Yuksel ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Hip Fracture ◽  
Kidney Injury ◽  
The Elderly ◽  
Elderly Individuals ◽  
Hip Fracture Surgery ◽  
Surgery In The Elderly ◽  
Fracture Surgery

scholarly journals The prevalence and risk factors of acute kidney injury in patients undergoing hip fracture surgery: a meta-analysis

Bioengineered ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 1976-1985
Author(s):  
Zi-Cai Li ◽  
Yan-Chuan Pu ◽  
Jin Wang ◽  
Hu-Lin Wang ◽  
Yan-Li Zhang
Keyword(s):  
Risk Factors ◽  
Acute Kidney Injury ◽  
Hip Fracture ◽  
Meta Analysis ◽  
Kidney Injury ◽  
Hip Fracture Surgery ◽  
Fracture Surgery
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