Lactulose: a prebiotic, laxative and detoxifying agent

2017 ◽  
Vol 33 (5) ◽  
pp. 228-233 ◽  
Author(s):  
Dhiren Pranami ◽  
Ramandeep Sharma ◽  
Hardik Pathak
Keyword(s):  
Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1906
Author(s):  
Phraepakaporn Kunnaja ◽  
Sunee Chansakaow ◽  
Absorn Wittayapraparat ◽  
Pedcharada Yusuk ◽  
Seewaboon Sireeratawong

In Thailand, people in the highland communities whose occupational exposure to pesticides used the root of Litsea martabanica as a detoxifying agent. However, the scientific data to support the traditional use of this plant are insufficient. This study aimed to evaluate the antioxidant activity and anti-pesticide potential of L. martabanica root extract. Antioxidant properties were investigated by 2,2′-diphenyl-1-picrylhydrazyl (DPPH) assay, superoxide radicals scavenging assay, 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay, ferric reducing antioxidant power (FRAP), and total phenolic content determination. In all assays, L. martabanica extracts and their fractions exhibited high antioxidant activities differently. The water extract is traditionally used as a detoxifying agent. Therefore, it was chosen for in vivo experiments. The rats received the extract in a way that mimics the traditional methods of tribal communities followed by chlorpyrifos for 16 days. The results showed that acetylcholinesterase activity decreases in pesticide-exposed rats. Treatment with the extract caused increasing acetylcholinesterase activity in the rats. Therefore, L. martabanica extract may potentially be used as a detoxifying agent, especially for the chlorpyrifos pesticide. The antioxidant properties of L. martabanica may provide a beneficial effect by protecting liver cells from damage caused by free radicals. Histopathology results revealed no liver cell necrosis and showed the regeneration of liver cells in the treatment group. L. martabanica extract did not cause changes in behavior, liver weight, hematological and biochemical profiles of the rats.


Food Control ◽  
2016 ◽  
Vol 68 ◽  
pp. 271-279 ◽  
Author(s):  
Mengling He ◽  
Yun Li ◽  
Fuwei Pi ◽  
Jian Ji ◽  
Xingxing He ◽  
...  

2021 ◽  
Vol 258 ◽  
pp. 08023
Author(s):  
Alevtina Kulikova ◽  
Vitaly Isaichev ◽  
Andrey Kozlov ◽  
Olga Tsapovskaya

The article presents the results of studying the toxic levels of mobile copper in typical chernozem by doing model field experiments with artificial soil contamination with copper sulfate at a level of 2 MPC Cu, 4 MPC Cu and 10 MPC Cu. It was shown that this increased the content of mobile copper from 1.4 (2 MPC Cu) to 2.0 times (10 MPC Cu) when copper was extracted from the soil, respectively, with an acetate-ammonium buffer solution of pH 4.8 and 1n HCl solution. The latter was accompanied by the loss of almost a third of the spring wheat yield (29%) and an increase in the entry of the element into produce (grain). The application of diatomite to the soil (dose 5 t / ha) as a detoxifying agent contributed to a decrease in the level of copper in the spring wheat produce by 8 (2 MPC Cu) and 35 (10 MPC Cu)%.


The Lancet ◽  
1983 ◽  
Vol 321 (8329) ◽  
pp. 880-881 ◽  
Author(s):  
Jack Cameron

1967 ◽  
Vol 45 (4) ◽  
pp. 705-715 ◽  
Author(s):  
Thomas M. S. Chang ◽  
Linda J. Johnson ◽  
Oscar J. Ransome

Stable nonthrombogenic microcapsules of 4 to 200 μ mean diameter consisting of a protein or detoxifying agent enclosed within thin semipermeable benzal-konium–heparin complexed polymer membranes were prepared. Such microcapsules did not cause clot formation in a nonthrombogenic extracorporeal shunt chamber when perfused for several hours by circulating blood which had normal clotting time. The enclosed enzyme retained its catalytic activity.


2020 ◽  
Vol 242 ◽  
pp. 104295
Author(s):  
Jog Raj ◽  
Marko Vasiljević ◽  
Panagiotis Tassis ◽  
Hunor Farkaš ◽  
Klaus Männer

Sign in / Sign up

Export Citation Format

Share Document