Medications and fall risk: a case–control study in nursing home residents in Japan

2019 ◽  
Vol 32 (5) ◽  
pp. 885-892 ◽  
Author(s):  
Hyerim Park ◽  
Hiroki Satoh ◽  
Akiko Miki ◽  
Hideyuki Maki ◽  
Kohei Asai ◽  
...  
2016 ◽  
Vol 64 (4) ◽  
pp. 911-912 ◽  
Author(s):  
Rui Niimi ◽  
Toshibumi Kono ◽  
Atsushi Nishihara ◽  
Masahiro Hasegawa ◽  
Akihiko Matsumine ◽  
...  

2015 ◽  
Vol 36 (5) ◽  
pp. 575-577 ◽  
Author(s):  
Sara Manning ◽  
Ebbing Lautenbach ◽  
Pam Tolomeo ◽  
Jennifer H. Han

A case-control study to determine risk factors for clinical infection with Escherichia coli was conducted among nursing home residents colonized with fluoroquinolone-resistant E. coli. Among 94 subjects, 11 (12%) developed infections with E. coli. Risk factors included the presence of a urinary catheter or tracheostomy, diabetes mellitus, and trimethoprim-sulfamethoxazole exposure.Infect Control Hosp Epidemiol 2015;00(0): 1–3


2019 ◽  
Vol 70 (4) ◽  
pp. 1113-1122 ◽  
Author(s):  
Pilar Pérez-Ros ◽  
Francisco Miguel Martínez-Arnau ◽  
Susana Baixauli-Alacreu ◽  
Mireia Caballero-Pérez ◽  
José Fermín García-Gollarte ◽  
...  

1985 ◽  
Vol 33 (5) ◽  
pp. 315-319 ◽  
Author(s):  
Michael J. Lichtenstein ◽  
Charles F. Federspiel ◽  
William Schaffner

2018 ◽  
Vol 75 (3) ◽  
pp. 563-572 ◽  
Author(s):  
Isis M. Severo ◽  
Ricardo Kuchenbecker ◽  
Débora F. V. B. Vieira ◽  
Luciana R. C. Pinto ◽  
Michele E. W. Hervé ◽  
...  

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
N Tiwana ◽  
A Pietronigro ◽  
M Mosillo ◽  
N Principi ◽  
D Carnevali ◽  
...  

Abstract Background Falls and fall-related injuries are a major public health issue which needs global attention due to its clinical and socioeconomic impact. Inpatient falls are the most common adverse event in hospital. Important risk factors for falls are polypharmacy and the assumption of so-called Fall Risk Increasing Drugs (FRIDs). Aims of our study were to investigate the associations between falls and the use of medications among inpatients by conducting a retrospective case-control study in a rehabilitation hospital in Northern Italy in 2018. Methods Three unique control for each faller, matched by age, sex and hospitalization ward, were selected. A Conditional Logistic Regression was performed to analyze the impact that 13 types of FRIDs individually and the number of administrated FRIDs had on the risk of falling. A second regression model was obtained adjusting the case-control matching for CIRS, Morse and Barthel scores. Results We identified 148 cases and 444 controls. 3 types of FRIDs were significantly correlated (p < 0,05) with an increased risk of falling: Antipsychotics [OR:1,98;CI 95%:1,01-3,89], Antidepressants [OR:2,18;CI 95%:1,32-3,59], Diuretics [OR:1,71;CI 95%:1,09-2,68]. Antidepressants were the only type of FRID significantly correlated (p = 0,008) even in the model adjusted for CIRS, Morse and Barthel scores [OR:2,00;CI 95%:1,20-3,34]. The unadjusted model showed that the addition of one type of FRID to therapy was significantly associated with the fall event (p < 0.05) [OR:1.21;CI 95%: 1.05 - 1.40]. Conclusions Assumption of drugs and polypharmacy could play a role in hospital falling. Recently developed fall risk assessment tools suffer from low specificity and sensitivity and do not assess these risk factors. A holistic approach with a multidimensional evaluation of the patient through screening tools, functional assessment tools and a full medical evaluation should be improved. Key messages Drugs may represent an important variable in determining the risk of falls in hospitalized patients, but they should not be considered alone. Screening tools for fall risk should take into account polypharmacy such as other intrinsic and extrinsic risk factors within an holistic approach.


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