Chronic acidosis with metabolic bone disease. Effect of alkali on bone morphology and vitamin D metabolism

Hypervitaminosis D is one of the causes of severe hypercalcemia in children. Most cases of hypervitaminosis D during childhood are due to an excessive supplementation of vitamin D by physicians or parents.1,2 To prevent metabolic bone disease of prematurity (rickets of prematurity), formulas designed for premature infants ("premature formulas"), which contain more calcium and vitamin D than standard formulas, are given to premature infants in addition to human milk.1 In some cases, separate vitamin D products are also given to these infants, although requirements for vitamin D and calcium intake in the premature infant and the formerly premature infant have not been fully estimated.1

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Privational and malabsorption metabolic bone disease: Plasma vitamin D metabolite concentrations and their relationship to quantitative bone histology

Metabolic Bone Disease and Related Research ◽

10.1016/0221-8747(81)90003-5 ◽

1981 ◽

Vol 3 (3) ◽

pp. 165-170 ◽

Cited By ~ 5

Author(s):

J.E. Compston ◽

S. Vedi ◽

A.L. Merrett ◽

T.L. Clemens ◽

J.L.H. O'Riordan ◽

...

Keyword(s):

Vitamin D ◽

Bone Disease ◽

Metabolic Bone Disease ◽

Bone Histology ◽

Plasma Vitamin ◽

Metabolic Bone ◽

Metabolite Concentrations ◽

Quantitative Bone Histology

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Recent advances in pediatric metabolic bone disease: the consequences of altered phosphate homeostasis in renal insufficiency and hypophosphatemic vitamin D-resistant rickets

Bone and Mineral ◽

10.1016/0169-6009(90)90038-h ◽

1990 ◽

Vol 9 (3) ◽

pp. 199-214 ◽

Cited By ~ 4

Author(s):

John M. Pettifor

Keyword(s):

Vitamin D ◽

Renal Insufficiency ◽

Bone Disease ◽

Metabolic Bone Disease ◽

Phosphate Homeostasis ◽

Recent Advances ◽

Metabolic Bone ◽

Vitamin D Resistant Rickets ◽

Resistant Rickets

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Are There Hallmarks of Child Abuse? I. Osseous Injuries

Academic Forensic Pathology ◽

10.23907/2016.056 ◽

2016 ◽

Vol 6 (4) ◽

pp. 568-590

Author(s):

Alfredo Walker ◽

Charis Kepron ◽

Christopher M. Milroy

Keyword(s):

Vitamin D ◽

Child Abuse ◽

Young Children ◽

Vitamin D Deficiency ◽

Bone Disease ◽

Metabolic Bone Disease ◽

Rib Fractures ◽

Metabolic Bone ◽

Deficiency Rickets ◽

Metaphyseal Fractures

Fractures are commonly found in cases regarded as child abuse. The most commonly encountered fractures are to the ribs and the metaphyses. This paper examines the specificity of the classical metaphyseal lesion (CML) and rib fractures as hallmarks of child abuse. Recently, vitamin D deficiency (rickets) has been proposed as an alternative cause for the appearances typically described in CML. The literature in this area is examined. Rib fractures have also been highly associated with child abuse, particularly posterior rib fractures. As well as metabolic bone disease, resuscitation has been examined as a cause of rib fractures in young children. The current literature remains strongly supportive of rib fractures and metaphyseal fractures being indicators of child abuse.

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Metabolic Bone Disease in the CAPD Patient

Peritoneal Dialysis International ◽

10.1177/089686088300301s08 ◽

1983 ◽

Vol 3 (1_suppl) ◽

pp. 24-26 ◽

Cited By ~ 3

Author(s):

Francisco Llach

Keyword(s):

Vitamin D ◽

Renal Osteodystrophy ◽

Bone Disease ◽

Metabolic Bone Disease ◽

Osteitis Fibrosa ◽

Prospective Evaluation ◽

Metabolic Bone ◽

Capd Patient

It seems that CAPD may improve some patients with osteomalacia but may be similar to hemodialysis in regard to osteitis fibrosa. However, long-term prospective evaluation of the incidence of bone disease in CAPD patients is necessary before we can determine how CAPD may alter the incidence and expression of renal osteodystrophy. We need more information before we can conclude that CAPD may improve pure osteomalacia. Finally, the data available are insufficient to clarify the role of vitamin D analogues in these patients.

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