The Bronze Age People of Ban Kao: A Preliminary Analysis of the Human Remains from Ban Ta Po Archaeological Site, Western Thailand | คนสมัยส􀄬ำริดที่บ้ำนเก่ำ : รำยงำนขั้นต้นผลกำรวิเครำะห์โครงกระดูกมนุษย์จำกแหล่ง โบรำณคดีบ้ำนท่ำโป๊ะ ในภำคตะวันตกของประเทศไทย

Ban Ta Po is located in the Ban Kao Subdistrict within an area that the Thai-Danish Expedition uncovered the famous Neolithic Ban Kao Culture in 1960. The two-season excavation in 2018 and 2020 discovered 17 burials dated to the Bronze age. The analysis of these individuals that were buried there were mostly infants and children. Two children appeared with some disease lesions on bones like porous on the cranium, a carious tooth related to the localized enamel hypoplasia, and the femoral bowing. All possibly indicate metabolic bone disease caused by a nutrition deficiency.

Hypophosphatemia and Metabolic Bone Disease Associated With the Use of Elemental Formula: Case Report and Review

A small percentage of infants and children develop cow’s milk protein allergy which is usually treated with exclusive breastfeeding or extensively hydrolyzed formulas. Some children might still be reactive to hydrolyzed formulas and would need elemental amino acid-based formulas. Elemental formulas are also frequently employed in treating very low birth weight babies with significant intolerance to regular preterm formulas and the resulting poor growth. All pediatric formulas are usually prepared as per international guidelines to fulfill the macro- and micronutrient requirements of growing children across a wide range of volume intakes. However, an interesting correlation is being reported recently, between the use of a specific elemental formula and the development of hypophosphatemia and significant metabolic bone disease. We discuss this phenomenon by exploring the available evidence and report 2 similar cases that we managed in our practice.

Analysis of the Clinical Features of Intrauterine Ureaplasma urealyticum Infection in Preterm Infants: A Case-Control Study

Objective: To analyze the clinical characteristics of intrauterine Ureaplasma urealyticum (UU) infection in premature infants.Method: In this single-center retrospective case-control study, 291 preterm infants born in our hospital and hospitalized in our department and gestational age no more than 32 weeks, birth weight no more than 2000 g were included from January 2019 to January 2021. Lower respiratory tract secretion, gastric fluid and urine were collected for UU RNA detection within 48 h after birth. Intrauterine UU infection is defined by at least one positive UU-PCR test of secreta or excreta of preterm infants after birth. The UU infection group included 86 preterm infants and the non-UU infection group included 205 preterm infants. We compared their clinical features, hemogram changes and disease outcomes using statistical analyses.Results: The clinical characteristics of premature infants such as the duration of oxygen use and ventilator use in hospital were significantly prolonged in the UU infection group (P < 0.05). The levels of leukocytes, platelet and procalcitonin in the UU infection group were significantly higher than in the non-UU infection group (P < 0.05). In terms of preterm complications, only the incidences of bronchopulmonary dysplasia, retinopathy of prematurity and metabolic bone disease in premature infants in the UU infection group were significantly higher than those in the non-UU infection group (P < 0.05). The mode of delivery, maternal premature rupture of membranes, and postnatal leukocyte level were independent risk factors for UU infection, while gestational hypertension was a protective factor for UU infection. The level of leukocytes in postnatal hemogram of premature infants could be used as a diagnostic index of UU infection, but the diagnostic accuracy was poor.Conclusion: In our study, UU infection can increase the incidence of bronchopulmonary dysplasia, retinopathy of prematurity and metabolic bone disease in preterm infants, but have no effect on the incidence of necrotizing enterocolitis, intracranial hemorrhage, white matter damage and other diseases in preterm infants. For high-risk premature infants, UU should be detected as soon as possible after birth, early intervention and drug treatment necessarily can improve the prognosis as much as possible.

The effect of Sandhaniya Mahakashaya along with diet and exercises in management of Jarawashtha Astikshaya and Astibhagna with special reference to Osteoporosis- A Review

Ayurveda is the science of life and longevity with the aim of prevention of disease, rejuvenation of our body system. Asthi is the fifth important dhatu. Astikshaya is the condition in which there is kshaya of Asthi dhatu commonly occurring in elderly people. Astikshaya may be compared to Osteoporosis. Osteoporosis is second most common metabolic bone disease in India, in which there is decrease in bone mass leading to bone fragility and consequently increasing the chances of frature. In Jarawashtha due to vitiation of vatta dosha kshaya of all dhatus occur including asthi. Ayurveda described jara is svabhavachvyadhi and it is prone to vata related disorder. Vattaprakopa leads to Astikshaya and his pathology can be treated with proper diet plan with dietary habits and lifestyle mentioned in Ayurveda. Rasayanchikitsa can also include with diet. Rasayanadravya is a drug to promote all dhatus. These drugs like mentioned by Charaka in sandhaniyagana give nourishment to Asthi dhatu.