Adverse drug effects attributed to phenylpropanolamine: A review of 142 case reports

1990 ◽  
Vol 89 (2) ◽  
pp. 195-208 ◽  
Author(s):  
C.Raymond Lake ◽  
Sheryle Gallant ◽  
Elizabeth Masson ◽  
Peggy Miller
Keyword(s):  
Case Reports ◽  
Drug Effects ◽  
Adverse Drug Effects

Fracture Healing

2015 ◽  
Vol 105 (2) ◽  
pp. 160-172 ◽  
Author(s):  
Robert G. Smith
Keyword(s):  
Adverse Effects ◽  
Fracture Healing ◽  
Bone Health ◽  
Case Reports ◽  
Drug Effects ◽  
Delayed Union ◽  
Adverse Drug Effects ◽  
Drug Adverse Effects ◽  
Definitive Statement ◽  
Medical Causation

Background Recognizing the existence of adverse drug effects of frequently prescribed drugs can empower a clinician with knowledge to avoid dangerous adverse effects that may result in hazardous, negative patient outcomes on either fracture healing or bone health. Pharmacovigilance reports have described the influence of medications, allowing for bone health to be quite unpredictable. Methods First, mechanisms found in the medical literature of potential drug adverse effects regarding fracture healing are presented. Second, the 100 most frequently prescribed medications in 2010 are reviewed regarding adverse effects on fracture healing. These reported adverse effects are evaluated for medical causation. Last, a data table describing the 100 reviewed medications and their reported effects on fracture healing is provided. Results The actual number of different medications in the review was 72. Reported drug adverse effects on bone and fracture healing occurred with 59 of the 72 drugs (81.9%). These adverse effects are either described as a definitive statement or represented by postmarketing case reports. Thirteen of the 72 review drugs (18.1%) did not have any description of the possible effects on bone health. A total of 301 cases reports describing delayed union, malunion, and nonunion of fractures represent 31 of the 72 medications reviewed (43.1%). Conclusions This review offers the health-care provider information regarding potential adverse drug effects on bone health. Empowered with this information, clinicians may assist their patients in maximizing pharmacologic outcomes by avoiding these reported harmful adverse effects.

Incidence rate of adverse drug effects in a hospital emergency unit and its associated factors

2010 ◽  
Vol 34 (6) ◽  
pp. 271-278
Author(s):  
S. Ramos Linares ◽  
P. DíazRuiz ◽  
J. Mesa Fumero ◽  
S. Núñez Díaz ◽  
M. Suárez González ◽  
...  
Keyword(s):  
Incidence Rate ◽  
Associated Factors ◽  
Drug Effects ◽  
Emergency Unit ◽  
Adverse Drug Effects ◽  
Hospital Emergency

scholarly journals Machine learning-based prediction of adverse drug effects: An example of seizure-inducing compounds

2017 ◽  
Vol 133 (2) ◽  
pp. 70-78 ◽  
Author(s):  
Mengxuan Gao ◽  
Hideyoshi Igata ◽  
Aoi Takeuchi ◽  
Kaoru Sato ◽  
Yuji Ikegaya
Keyword(s):  
Machine Learning ◽  
Drug Effects ◽  
Adverse Drug Effects

Pharmacognostic, Phytochemical and Therapeutic Overview of three Allied Herbs used in Dentistry

2021 ◽  
Vol 11 (2) ◽  
pp. 121-125
Author(s):  
Deepak Prashar ◽  
Khushboo Jasra
Keyword(s):  
Chemical Composition ◽  
Drug Effects ◽  
Present Review ◽  
Adverse Drug Effects ◽  
Therapeutic Role

The dental herbs are very much essential for the treatment of many dental problems. They can be used as such or in the form of dental formulations. These dental formulations of the herbs have enormous economical importance too. Apart from the pharmaco-therapeutic role the pharmacognostic and it’s chemical composition is also essential. These parameters help to modify the formulations and to overcome the adverse drug effects associated with these. The present review work tries to highlight the Pharmacognostic and Phytochemical aspects of three dental herbs.

Pharmaco-EcoMicrobiology and Its Potential Role in Medical and Environmental Sciences

2012 ◽  
pp. 291-302
Author(s):  
Mohd. Shahid ◽  
Hridesh Mishra ◽  
Hemant Kumar Mishra ◽  
Trivendra Tripathi ◽  
Haris M. Khan ◽  
...  
Keyword(s):  
Information Technologies ◽  
Antimicrobial Agents ◽  
Drug Effects ◽  
Pharmacy Education ◽  
World Health ◽  
Adverse Drug Effects ◽  
Pharmaceutical Industries ◽  
Health Organization

Despite the call of the World Health Organization (WHO) for “Pharmacovigilance,” i.e. the monitoring, detection, assessment, and prevention of any adverse reactions, poor attention has been given to identify the long term and short term Adverse Effects (ADEs) of antimicrobial agents on the environment. It is obvious that most of the health sectors across the globe are occupied by infectious diseases (e.g. tuberculosis, HIV, and hepatitis), and to combat such threats, the pharmaceutical industries are pouring tons of drugs and reagents into a market worth billions of dollars. The discharge of these products into the ecosystem is potentially a threat to the environment and human health. In this chapter, the authors depicted a recently described terminology, “Pharmaco-EcoMicrobiology” (PEcM), that could cover these problems and their possible solutions on medical and environmental aspects. In this regard, the role of pharmacoinformatics could also be crucial, since it can provide swift information for implementation and use of information technologies for the discovery and development of drugs as well as in pharmacy education and also the detection and combat of adverse drug effects.

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