Correlation between of MRI hippocampal atrophy and scalp EEG ictal discharge frequency during complex partial seizures (CPS) in surgically-proven temporal lobe epilepsy: a pilot study

1996 ◽  
Vol 99 (3) ◽  
pp. 22
Author(s):  
David G. Vossler ◽  
Robert J. Wilkus ◽  
Allen R. Wyler ◽  
Diana L. Kraemer ◽  
Bent O. Kjos
Keyword(s):  
Pilot Study ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Discharge Frequency ◽  
Hippocampal Atrophy ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Scalp Eeg

scholarly journals Neocortical Temporal Lobe Epilepsy

2012 ◽  
Vol 2012 ◽  
pp. 1-15 ◽  
Author(s):  
Eduard Bercovici ◽  
Balagobal Santosh Kumar ◽  
Seyed M. Mirsattari
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Mesial Temporal Lobe Epilepsy ◽  
Functional Brain Imaging ◽  
Disease Entity ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Reciprocal Connections ◽  
Mesial Temporal Lobe ◽  
Poor Outcomes

Complex partial seizures (CPSs) can present with various semiologies, while mesial temporal lobe epilepsy (mTLE) is a well-recognized cause of CPS, neocortical temporal lobe epilepsy (nTLE) albeit being less common is increasingly recognized as separate disease entity. Differentiating the two remains a challenge for epileptologists as many symptoms overlap due to reciprocal connections between the neocortical and the mesial temporal regions. Various studies have attempted to correctly localize the seizure focus in nTLE as patients with this disorder may benefit from surgery. While earlier work predicted poor outcomes in this population, recent work challenges those ideas yielding good outcomes in part due to better localization using improved anatomical and functional techniques. This paper provides a comprehensive review of the diagnostic workup, particularly the application of recent advances in electroencephalography and functional brain imaging, in neocortical temporal lobe epilepsy.

scholarly journals Quantifying Interictal Metabolic Activity in Human Temporal Lobe Epilepsy

1990 ◽  
Vol 10 (5) ◽  
pp. 748-757 ◽  
Author(s):  
Thomas R. Henry ◽  
John C. Mazziotta ◽  
Jerome Engel ◽  
Peter D. Christenson ◽  
Jing Xi Zhang ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Fdg Pet ◽  
Emission Tomography ◽  
Normal Brain ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Anatomical Analysis ◽  
Positron Emission ◽  
Human Temporal Lobe

The majority of patients with complex partial seizures of unilateral temporal lobe origin have interictal temporal hypometabolism on [18F]fluorodeoxyglucose positron emission tomography (FDG PET) studies. Often, this hypometabolism extends to ipsilateral extratemporal sites. The use of accurately quantified metabolic data has been limited by the absence of an equally reliable method of anatomical analysis of PET images. We developed a standardized method for visual placement of anatomically configured regions of interest on FDG PET studies, which is particularly adapted to the widespread, asymmetric, and often severe interictal metabolic alterations of temporal lobe epilepsy. This method was applied by a single investigator, who was blind to the identity of subjects, to 10 normal control and 25 interictal temporal lobe epilepsy studies. All subjects had normal brain anatomical volumes on structural neuroimaging studies. The results demonstrate ipsilateral thalamic and temporal lobe involvement in the interictal hypometabolism of unilateral temporal lobe epilepsy. Ipsilateral frontal, parietal, and basal ganglial metabolism is also reduced, although not as markedly as is temporal and thalamic metabolism.

scholarly journals Scott Fitzgerald: famous writer, alcoholism and probable epilepsy

2017 ◽  
Vol 75 (1) ◽  
pp. 66-68
Author(s):  
Mariana M. Wolski ◽  
Luciano de Paola ◽  
Hélio A. G. Teive
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Alcohol Dependence ◽  
Temporal Lobe ◽  
Ernest Hemingway ◽  
Health Problems ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
American Writer

ABSTRACT Scott Fitzgerald, a world-renowned American writer, suffered from various health problems, particularly alcohol dependence, and died suddenly at the age of 44. According to descriptions in A Moveable Feast, by Ernest Hemingway, Fitzgerald had episodes resembling complex partial seizures, raising the possibility of temporal lobe epilepsy.

scholarly journals Functional significance of MRI defined mesial temporal sclerosis in temporal lobe epilepsy

1994 ◽  
Vol 52 (3) ◽  
pp. 295-300
Author(s):  
Elza Márcia T. Yacubian ◽  
Arthur Cukiert ◽  
Paulo Carrilho ◽  
Carmen Lisa Jorge ◽  
Lia Arno Fiore ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Functional Significance ◽  
Epileptic Focus ◽  
Mesial Temporal Sclerosis ◽  
Complex Partial Seizures ◽  
Sharp Waves ◽  
Scalp Eeg ◽  
Group I ◽  
Group Ii

The functional significance of MRI-defined mesial temporal sclerosis in temporal lobe epilepsy (TLE) is not completely established. In order to study the possible relationship between signals of mesial temporal sclerosis on MRI and interictal SPECT findings we selected 18 patients with complex partial seizures, unilateral temporal EEG focus and normal CT. The EEG focus was defined by the presence of interictal sharp waves and slow background on several scalp EEG obtained during many years of follow up in all patients and by ictal recordings with sphenoidal electrodes in 12 patients. Group I comprised patients (n=11) in whom MRI showed mesial temporal sclerosis; group II patients (n=7) had normal MRIs. All patients were submitted to interictal 99m-Tc HMPAO injections with concomitant EEG monitoring. Lateralized hypoperfusion ipsilateral to the EEG was found in 13 patients (72%). In all Group II and in 6 Group I patients a temporal hypoperfusion was found. This SPECT study showed a higher positivity rate in patients with normal MRI than previously reported. On the other hand, in all these group II patients a neocortical origin of epileptic focus was suspected on clinical or electroencephalographic basis. Positive SPECT findings may be at least as prevalent in neocortical as in mesiolimbic epilepsy.

Neuropsychiatrie and Electroencephalographic Aspects in the Diagnosis of Complex Partial Seizures

1981 ◽  
Vol 26 (1) ◽  
pp. 49-52 ◽  
Author(s):  
Ronald A. Remick ◽  
Juhn A. Wada ◽  
James E. Miles
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Partial Seizures ◽  
Appropriate Use ◽  
Complex Partial Seizures ◽  
Eeg Abnormalities ◽  
Sleep Recording

The authors review from a psychiatric perspective some of the electroencephalographic techniques that may assist the clinician in diagnosing complex partial seizures (temporal lobe epilepsy). Routine scalp electroencephalograms may not detect temporal lobe EEG abnormalities, leading to the false impression of pseudo or hysterical seizures. Knowledge of the advantages of a sleep recording, specialized EEG electrodes (nasopharyngeal, sphenoidal), and natural or pharmacological activation techniques will increase one's diagnostic acumen. The authors discuss the appropriate use of these methods and their relevance to psychiatry.

scholarly journals Insular epilepsy: similarities to temporal lobe epilepsy case report

1998 ◽  
Vol 56 (1) ◽  
pp. 126-128 ◽  
Author(s):  
ARTHUR CUKIERT ◽  
CASSIO FORSTER ◽  
MARIO S.D. ANDRIOLI ◽  
LEILA FRAYMAN
Keyword(s):  
Case Report ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Neuropsychological Testing ◽  
Cavernous Angioma ◽  
Sylvian Fissure ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Brain Surface ◽  
The Brain

Insular epilepsy has been rarely reported and its clinical and electrographic features are poorly understood. The electrographic study of the insula is difficult since it is hidden from the brain surface by the frontal and temporal lobe. A 48 years-old woman started having simple partial autonomic and complex partial seizures with automatisms and ictal left arm paresis 8 years prior to admission. Seizure's frequency was 1 per week. Pre-operative EEG showed a right temporal lobe focus. Neuropsychological testing disclosed right fronto-temporal dysfunction. MRI showed a right anterior insular cavernous angioma. Intraoperative ECoG obtained after spliting of the sylvian fissure showed independent spiking from the insula and temporal lobe and insular spikes that spread to the temporal lobe. The cavernous angioma and the surrounding gliotic tissue were removed and the temporal lobe was left in place. Post-resection ECoG still disclosed independent temporal and insular spiking with a lower frequency. The patient has been seizure-free since surgery. Insular epilepsy may share many clinical and electroencephalographic features with temporal lobe epilepsy.

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