Separation of three compositionally distinct subclasses of rat high density lipoproteins by heparin-affinity chromatography

1988 ◽  
Vol 70 (3) ◽  
pp. 205-215 ◽  
Author(s):  
Christine C. Lee ◽  
Sung I. Koo
Keyword(s):  
Affinity Chromatography ◽  
High Density ◽  
High Density Lipoproteins ◽  
Heparin Affinity

scholarly journals Importance of Apolipoprotein A-I and A-II Composition in HDL and Its Potential for Studying COVID-19 and SARS-CoV-2

Medicines ◽  
2021 ◽  
Vol 8 (7) ◽  
pp. 38
Author(s):  
Kyung-Hyun Cho
Keyword(s):  
Antiviral Activity ◽  
High Density ◽  
High Density Lipoproteins ◽  
Potent Antiviral Activity ◽  
Apolipoprotein A ◽  
Putative Role

The composition and properties of apolipoprotein (apo) A-I and apoA-II in high-density lipoproteins (HDL) might be critical to SARS-CoV-2 infection via SR-BI and antiviral activity against COVID-19. HDL containing native apoA-I showed potent antiviral activity, while HDL containing glycated apoA-I or other apolipoproteins did not. However, there has been no report to elucidate the putative role of apoA-II in the antiviral activity of HDL.

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