Uptake of [3H]-catecholamines by homogenates of rat corpus striatum and cerebral cortex: Effects of amphetamine analogues

1973 ◽  
Vol 12 (7) ◽  
pp. 669-679 ◽  
Author(s):  
Jane E. Harris ◽  
R.J. Baldessarinig
1996 ◽  
Vol 24 (01) ◽  
pp. 53-64 ◽  
Author(s):  
Tadanobu ltoh ◽  
Seisuke Michijiri ◽  
Shigeo Murai ◽  
Hiroko Saito ◽  
Hiroshi Saito ◽  
...  

The effects of the extract powder (CggT) from Chaihu-Guizhi-Gajiang-Tang (Saiko-keishi-kankyo-to, in Japanese) on the monoamines and their related substances and the acetylcholine in mouse brain were examined. 1) A single administration of CggT significantly increased the levels of HVA and 5-HIAA in the cerebral cortex, hypothalamus, corpus striatum and hippocampus at 75 mg/kg, and those in the hypothalamus, corpus striatum and hippocampus at 750 mg/kg. 2) The repeated administration of CggT significantly increased the level of 5-HT in the hippocampus at 75 mg/kg, and the levels of 5-HT in the corpus striatum and of NE and 5-HT in the hippocampus at 750 mg/kg. 3) The level of ACh was significantly increased in the hypothalamus alone after single administration of CggT. These findings suggest that CggT stimulates function of the dopaminergic and serotonergic nervous systems in mice, but not most of the NEnergic and cholinergic nervous systems.


1989 ◽  
Vol 20 (6) ◽  
pp. 725-729 ◽  
Author(s):  
Edward W. Awad ◽  
Camille F. Nassar ◽  
Marwan S. Tabbara ◽  
Ghassan K. Abou-Alfa ◽  
Nayef E. Saadé ◽  
...  

2015 ◽  
Vol 14 (1) ◽  
pp. 52-54
Author(s):  
Vlad Claudiu Stefanescu ◽  
◽  
Irene Davidescu ◽  
Ioan Buraga ◽  
Bogdan Ovidiu Popescu ◽  
...  

Ischemic or hemorrhagic stroke may be accompanied by movement disorders (1), either hyperkinetic or hypokinetic. Hyperkinetic movement disorders after stroke comprise dystonia (2-4), chorea with or without hemiballismus (5), tremor (6), parkinsonism (7), segmental or focal myoclonus, athetosis, pseudathetosis, and asterixis (8). Hemiballismus is a movement disorder characterized by involuntary, arrythmic, and large amplitude excursion of a limb, usually from a proximal joint, witn an element of rotation (9). Ballismus is explainable with lesions in the subthalamic nuclei, cerebral cortex, corpus striatum, thalamus and brainstem. (10) The frequency of post-stroke abnormal movements is unclear, the prevalence in a swiss registry being 1% with an incidence of 0.08% per year (8). Of them, hemichorea-hemiballismus is the most common, while dystonia is the next most common disorder (11).


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