Substance P-, CGRP- and NPY-immunoreactive nerve fibers in rat sciatic nerve-end neuromas

1989 ◽  
Vol 25 (1) ◽  
pp. 11-24 ◽  
Author(s):  
K. Fried ◽  
E. Brodin ◽  
E. Theodorsson
Keyword(s):  
Substance P ◽  
Sciatic Nerve ◽  
Nerve Fibers ◽  
Rat Sciatic Nerve

Cytochemistry and morphometry of rat sciatic nerve following laser and suture treatments

1986 ◽  
Vol 44 ◽  
pp. 128-129
Author(s):  
A. Shah ◽  
J. E. Bailes ◽  
V. Sahgal ◽  
L. J. Cerullo
Keyword(s):  
Sciatic Nerve ◽  
Horseradish Peroxidase ◽  
Light Microscopy ◽  
Morphological Study ◽  
Wallerian Degeneration ◽  
Nerve Repair ◽  
Nerve Fibers ◽  
Relative Efficacy ◽  
Tracer Technique ◽  
Rat Sciatic Nerve

The success of nerve repair treatment can be measured by examining the factors (Wallerian degeneration) that prevent functional recovery, and determining the extent of regeneration of proximal axon sprouts in the endoneurial environment of the distal fascicles. In the present study, the neurosurgical alignment of fascicles was attempted by laser as well as suture microsurgery of transected rat sciatic nerve and the relative efficacy of the two procedures was evaluated after 6 and 12 weeks by Neurophysiological Study, Morphological Study with light microscopy, ultrastructure, and the permeability of blood-nerve barrier using horseradish peroxidase (HRP) tracer technique, and Morphometry of the nerve fibers.

Long-term axonal apposition in rat sciatic nerve neuroma

1982 ◽  
Vol 57 (5) ◽  
pp. 682-684 ◽  
Author(s):  
Jerald J. Bernstein ◽  
David Pagnanelli
Keyword(s):  
Sciatic Nerve ◽  
Cross Talk ◽  
Nerve Fibers ◽  
Sprague Dawley ◽  
Content Type ◽  
Rat Sciatic Nerve ◽  
Amputation Neuroma ◽  
Anatomical Basis ◽  
Unmyelinated Nerve

✓ Long-term electrophysiological cross-talk between nerve fibers has been demonstrated in rat sciatic nerve following induction of an amputation neuroma. Experiments were designed to establish an anatomical basis for this phenomenon. The sciatic nerve was transected and the epineurium oversewn with 10-0 nylon in 16 adult male Sprague-Dawley rats. The resulting neuromas were prepared for ultrastructural analysis 7, 14, 30, and 60 days later. An analysis of the unmyelinated nerve fibers showed normal configurations of the fibers, with normal organelles, separated by Schwann cell processes in the neuroma. However, degenerating unmyelinated nerve fibers and nerve fibers with masses of neurofilaments were often observed. In approximately 10% of the total population observed, there were two or more unmyelinated nerve fibers in a single Schwann process fascicle. Some of the multiple unmyelinated nerve fiber fascicles had nerve fibers that were in membranous apposition. This configuration of unmyelinated axons could form the anatomical basis for long-term physiological cross-talk between axons in a neuroma, and could be of consequence in pain production.

Conduction Block by Clonidine Is Not Mediated by α2-Adrenergic Receptors in Rat Sciatic Nerve Fibers

2000 ◽  
Vol 25 (6) ◽  
pp. 620-625 ◽  
Author(s):  
Joong Woo Leem ◽  
Yoon Choi ◽  
Song Min Han ◽  
Mi Ja Yoon ◽  
Ji Yeon Sim ◽  
...  
Keyword(s):  
Sciatic Nerve ◽  
Adrenergic Receptors ◽  
Conduction Block ◽  
Nerve Fibers ◽  
Rat Sciatic Nerve

Oxaliplatin-induced Hyperexcitation of Rat Sciatic Nerve Fibers: An Intra-axonal Study

2013 ◽  
Vol 13 (2) ◽  
pp. 373-379 ◽  
Author(s):  
Alexia Kagiava ◽  
Efstratios K. Kosmidis ◽  
George Theophilidis
Keyword(s):  
Sciatic Nerve ◽  
Nerve Fibers ◽  
Rat Sciatic Nerve
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