The relationship between measles virus infection and subacute sclerosing panencephalitis (SSPE)

1976 ◽  
Vol 2 (2) ◽  
pp. 55-57 ◽  
Author(s):  
D.H. Adams ◽  
T.M. Bell
2019 ◽  
Vol 37 (4) ◽  
pp. 205-208
Author(s):  
Gobinda Chandra Banik ◽  
Sakib Aman ◽  
Farhana Sultana ◽  
Syed Mohammad Arif

  Subacute sclerosing panencephalitis (SSPE) is chronic progressive encephalitis of childhood and young adoloscent due to persistent measles virus infection. This case illustrates a 14 year old girl presented with short history of intellectual decline, abnormal behavior, myoclonus and altered consciousness with suggestive neuroimaging mimicking metachromatic leucodystrophy. Subsequently she was diagnosed to be a case of Subacute sclerosing panencephalitis (SSPE) on the basis of Electroencephalography (EEG) and Cerebrospinal fluid(CSF) measles antibody titer. J Bangladesh Coll Phys Surg 2019; 37(4): 205-208


1996 ◽  
Vol 91 (2) ◽  
pp. 135-139 ◽  
Author(s):  
S. H. Isaacson ◽  
D. M. Asher ◽  
M. S. Godec ◽  
C. J. Gibbs ◽  
D. C. Gajdusek

2007 ◽  
Vol 65 (4a) ◽  
pp. 1030-1033 ◽  
Author(s):  
Marcelo Maroco Cruzeiro ◽  
Thiago Cardoso Vale ◽  
Leopoldo Antônio Pires ◽  
Gláucio Mendes Franco

Subacute sclerosing panencephalitis (SSPE) is a progressive inflammatory disorder of the central nervous system with both poor prognosis and high mortality. The disease has been related to a persistent and aberrant measles virus infection and no effective treatment has been available. We report a case of SSPE with atypical features including seizures at onset and a fulminant course in a 8 years-old boy who had been previously immunized against measles.


2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Roosy Aulakh ◽  
Abhimanyu Tiwari

Subacute sclerosing panencephalitis (SSPE) is a devastating “slow virus” brain disease resulting from persistent measles virus infection of neurons. The age at presentation is usually 8 to 11 years with onset usually occurring 2–10 years after measles infection. We report a 2-and-half-year-old boy who presented with progressively increasing myoclonic jerks and subtle cognitive decline. He was diagnosed as a case of SSPE based on clinical features, typical electroencephalographic finding, and elevated cerebrospinal fluid/serum measles antibody titers. He had measles 4 months prior to onset of symptoms. This case along with review of recently published reports suggests progressively decreasing latency period between measles infection and onset of symptoms observed in cases with SSPE. Clinical implication would mean investigating for SSPE even in infants or toddlers with compatible clinical features and recent history of measles infection.


The Lancet ◽  
1995 ◽  
Vol 345 (8957) ◽  
pp. 1124 ◽  
Author(s):  
K. Zwiauer ◽  
Elisabeth Forstenpointner ◽  
Therese Popow-Kraupp ◽  
E. Hauser ◽  
K.A. Jellinger

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