Chronic toxic effects of the carbamate pesticide sevin on carbohydrate metabolism in a freshwater snakehead fish, Channa punctatus

Ntroduction. The article is devoted to the study of the features of the metabolic pathology of the liver under the influence of harmful industrial factors. The relevance of the study of nonalcoholic fatty liver disease of workers in contact with industrial aerosols is due to the high prevalence of the disease among the working-age population, the polyethological nature of the pathology, including the pathogenetic relationship with external household and occupational toxic effects. Materials and methods. The were examined two hundred four industrial production workers, divided into four groups according to the composition of the affected aerosol: copper-nickel ore dust, welding aerosol, quartz-containing dust, carbon-based dust. The survey was conducted using the AUDIT questionnaire, examination of patients, anthropometry, ultrasound examination of the abdominal organs, biochemical blood analysis, determination of viral hepatitis B and C markers, and serum immunoglobulins. Results. The frequency of detection of ultrasonic signs of liver damage in the examined patients who came into contact with copper-nickel aerosol dust significantly exceeds the same indicator of the studied patients who came into contact with quartz-containing dust (p<0.05) and also exceeds the frequency of detection in the group working under the influence of carbon-based and welding aerosol (p>0.05). Most often, an increase in the activity of liver enzymes was noted among those working in contact with copper-nickel ore dust. Significant differences were found between groups 1 and 3; 1 and 4 (p<0.05). There were no significant differences between the groups in the frequency of lipid and carbohydrate metabolism disorders and biliary tract pathology. Discussion. The results of the study may be related to the toxic effects of the copper-nickel aerosol but may also be associated with the climatogeographic features of the workers ‘ habitat. Conclusion. The prevalence of liver diseases in the group that came into contact with copper-nickel dust was established. The revealed changes do not depend on lipid and carbohydrate metabolism features, pathology of the biliary tract. For a detailed study of liver damage in industrial workers, it is necessary to conduct an in-depth study.

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Fluoride Toxicity in the Fish Channa punctatus and its Reversibility by Ascorbic Acid

SRI JNPG COLLEGE REVELATION A JOURNAL OF POPULAR SCIENCE ◽

10.29320/sjnpgrj.v2i01.11033 ◽

2018 ◽

Vol 2 (01) ◽

Author(s):

Rajesh Gupta ◽

Krishna Gopal ◽

Madhu Tripathi ◽

U. D. Sharma

Keyword(s):

Ascorbic Acid ◽

Drinking Water ◽

Freshwater Fish ◽

Toxic Metals ◽

Channa Punctatus ◽

Toxic Effects ◽

Clean Water ◽

Fluoride Toxicity

Flouride toxicity has acquired a massive form in present times since we have to dig deeper and deeper in search of drinking water. Deeper levels are richer in toxic metals and non metals like Arsenic and Flourides. The present study takes a common freshwater fish Channa punctatus as a bioassay of fluoride toxicity and studies the effects of reversal of toxic effects by use of Ascorbic acid and by keeping the fish in clean water. The results have been compiled in the form of graphs and photomicrograph.

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HAEMATOLOGICAL CHANGES IN A FRESH WATER FISH, CHANNA PUNCTATUS UNDER CARTRIZ EXPOSURE

FLORA AND FAUNA ◽

10.33451/florafauna.v23i2pp411-414 ◽

2017 ◽

Vol 23 (2) ◽

Author(s):

MD. NOOR ALAM ◽

D.N. SADHU ◽

VIJAYA LAKSHAMI ◽

RENU PATHAK

Keyword(s):

Haemoglobin Concentration ◽

Channa Punctatus ◽

Total Leucocyte Count ◽

Fresh Water Fish ◽

Clotting Time ◽

Water Fish ◽

Haematological Changes ◽

Oxygen Carrying Capacity ◽

Carbamate Pesticide ◽

Rbc Count

Toxic effects of carbamate pesticide cartriz on the haematological characters in a facultative air breathing fish, Channa punctatus has been investigated in the present study. The intoxication of pesticide exhibited a significant decrease in RBC count, Haemoglobin concentration, packed cell volume (PCV) and oxygen carrying capacity of blood, whereas a progressive rise in total leucocyte count (TLC) and clotting time was observed in varying period of intoxication, revealing toxic nature of the agro chemical.

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Analysis of the influence of copper on carbohydrate metabolism in carp

International bulletin of Veterinary Medicine ◽

10.17238/issn2072-2419.2020.2.162 ◽

2020 ◽

Vol 2 ◽

pp. 162-165

Author(s):

L. Yu. Karpenko ◽

◽

P. A. Polistovskaya ◽

A. B. Balykina ◽

◽

...

Keyword(s):

Carbohydrate Metabolism ◽

Glucose Concentration ◽

Serum Amylase ◽

Amylase Activity ◽

Copper Acetate ◽

The Body ◽

Toxic Effects ◽

Control Group ◽

Toxic Substances ◽

Serum Amylase Activity

The article discusses some aspects of the toxic effects of copper acetate on the body of fish. Heavy metals are highly toxic to aquat-ic organisms due to their ability to accumu-late and transform within the biocenosis of the reservoir. The aim of the study was to study the indicators of carbohydrate metabo-lism in carp after exposure to various con-centrations of copper acetate. The study of the features of carbohydrate metabolism, including the intensity and direction of ex-change can be useful in assessing the re-sponse of fish to toxic effects. During the experiment, 4 groups of fish were formed - 1 control group (10 fish), 3 experimental groups – 10 fish each. Experimental groups of fish were contained in a solution of cop-per acetate (Cu(CH3COO)2) with concentra-tions of 0.01 mg/l, 0.1 mg/l, 1 mg/l (exceeding the MPC of copper for fisheries reservoirs by 10, 100 and 1000 times, re-spectively). Glucose concentration and se-rum amylase activity were studied. Glucose is necessary for supplying energy to various processes occurring inside the body,including reactions to toxic substances. Amylase, however, is an enzyme responsible for catalyzing the breakdown of complex carbohydrates. We found such changes in carbohydrate metabolism in carp as a signifi-cant increase in serum amylase activity by 6.63%, 7.9% and 19.57% when exposed to 10, 100 and 1000 MPC of copper, respec-tively, as well as a significant increase in glucose concentration by 8.54%, 20.28% and 29.7% when exposed to 10, 100 and 1000 MPC of copper, respectively, compared to the control group.

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