Toxic Effects of Dimethoate and Carbaryl Pesticides on Carbohydrate Metabolism of Freshwater Snail Lymnaea acuminata

2002 ◽  
Vol 68 (4) ◽  
pp. 606-611 ◽  
Author(s):  
P. Kumar Tripathi ◽  
A. Singh
Keyword(s):  
Carbohydrate Metabolism ◽  
Freshwater Snail ◽  
Toxic Effects ◽  
Lymnaea Acuminata

scholarly journals Features of metabolic pathology of the liver under the influence of industrial aerosols

2021 ◽  
Vol 100 (9) ◽  
pp. 943-946
Author(s):  
Marina V. Sheenkova ◽  
Oksana P. Rushkevich ◽  
Irina V. Yatsyna
Keyword(s):  
Carbohydrate Metabolism ◽  
Biliary Tract ◽  
Liver Damage ◽  
Blood Analysis ◽  
Toxic Effects ◽  
Industrial Workers ◽  
Nonalcoholic Fatty Liver ◽  
Copper Nickel ◽  
Pathology Of The Liver ◽  
Carbon Based

Ntroduction. The article is devoted to the study of the features of the metabolic pathology of the liver under the influence of harmful industrial factors. The relevance of the study of nonalcoholic fatty liver disease of workers in contact with industrial aerosols is due to the high prevalence of the disease among the working-age population, the polyethological nature of the pathology, including the pathogenetic relationship with external household and occupational toxic effects. Materials and methods. The were examined two hundred four industrial production workers, divided into four groups according to the composition of the affected aerosol: copper-nickel ore dust, welding aerosol, quartz-containing dust, carbon-based dust. The survey was conducted using the AUDIT questionnaire, examination of patients, anthropometry, ultrasound examination of the abdominal organs, biochemical blood analysis, determination of viral hepatitis B and C markers, and serum immunoglobulins. Results. The frequency of detection of ultrasonic signs of liver damage in the examined patients who came into contact with copper-nickel aerosol dust significantly exceeds the same indicator of the studied patients who came into contact with quartz-containing dust (p<0.05) and also exceeds the frequency of detection in the group working under the influence of carbon-based and welding aerosol (p>0.05). Most often, an increase in the activity of liver enzymes was noted among those working in contact with copper-nickel ore dust. Significant differences were found between groups 1 and 3; 1 and 4 (p<0.05). There were no significant differences between the groups in the frequency of lipid and carbohydrate metabolism disorders and biliary tract pathology. Discussion. The results of the study may be related to the toxic effects of the copper-nickel aerosol but may also be associated with the climatogeographic features of the workers ‘ habitat. Conclusion. The prevalence of liver diseases in the group that came into contact with copper-nickel dust was established. The revealed changes do not depend on lipid and carbohydrate metabolism features, pathology of the biliary tract. For a detailed study of liver damage in industrial workers, it is necessary to conduct an in-depth study.

Analysis of the influence of copper on carbohydrate metabolism in carp

2020 ◽  
Vol 2 ◽  
pp. 162-165
Author(s):  
L. Yu. Karpenko ◽  
◽  
P. A. Polistovskaya ◽  
A. B. Balykina ◽  
◽  
...  
Keyword(s):  
Carbohydrate Metabolism ◽  
Glucose Concentration ◽  
Serum Amylase ◽  
Amylase Activity ◽  
Copper Acetate ◽  
The Body ◽  
Toxic Effects ◽  
Control Group ◽  
Toxic Substances ◽  
Serum Amylase Activity

The article discusses some aspects of the toxic effects of copper acetate on the body of fish. Heavy metals are highly toxic to aquat-ic organisms due to their ability to accumu-late and transform within the biocenosis of the reservoir. The aim of the study was to study the indicators of carbohydrate metabo-lism in carp after exposure to various con-centrations of copper acetate. The study of the features of carbohydrate metabolism, including the intensity and direction of ex-change can be useful in assessing the re-sponse of fish to toxic effects. During the experiment, 4 groups of fish were formed - 1 control group (10 fish), 3 experimental groups – 10 fish each. Experimental groups of fish were contained in a solution of cop-per acetate (Cu(CH3COO)2) with concentra-tions of 0.01 mg/l, 0.1 mg/l, 1 mg/l (exceeding the MPC of copper for fisheries reservoirs by 10, 100 and 1000 times, re-spectively). Glucose concentration and se-rum amylase activity were studied. Glucose is necessary for supplying energy to various processes occurring inside the body,including reactions to toxic substances. Amylase, however, is an enzyme responsible for catalyzing the breakdown of complex carbohydrates. We found such changes in carbohydrate metabolism in carp as a signifi-cant increase in serum amylase activity by 6.63%, 7.9% and 19.57% when exposed to 10, 100 and 1000 MPC of copper, respec-tively, as well as a significant increase in glucose concentration by 8.54%, 20.28% and 29.7% when exposed to 10, 100 and 1000 MPC of copper, respectively, compared to the control group.

scholarly journals Enzyme Inhibition by Molluscicidal Components of Myristica fragrans Houtt. in the Nervous Tissue of Snail Lymnaea acuminata

2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Preetee Jaiswal ◽  
Pradeep Kumar ◽  
V. K. Singh ◽  
D. K. Singh
Keyword(s):  
Nervous Tissue ◽  
Freshwater Snail ◽  
Inhibition Kinetics ◽  
Acid And Alkaline Phosphatase ◽  
Myristica Fragrans ◽  
Myristica Fragrans Houtt ◽  
Kinetics Of ◽  
Lymnaea Acuminata

This study was designed to investigate the effects of molluscicidal components of Myristica fragrans Houtt. (Myristicaceae) on certain enzymes in the nervous tissue of freshwater snail Lymnaea acuminata Lamarck (Lymnaeidae). In vivo and in vitro treatments of trimyristin and myristicin (active molluscicidal components of Myristica fragrans Houtt.) significantly inhibited the acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. The inhibition kinetics of these enzymes indicates that both the trimyristin and myristicin caused competitive noncompetitive inhibition of AChE. Trimyristin caused uncompetitive and competitive/noncompetitive inhibitions of ACP and ALP, respectively whereas the myristicin caused competitive and uncompetitive inhibition of ACP and ALP, respectively. Thus results from the present study suggest that inhibition of AChE, ACP, and ALP by trimyristin and myristicin in the snail Lymnaea acuminata may be the cause of the molluscicidal activity of Myristica fragrans.

scholarly journals EFFECTS OF SINGLE, BINARY AND TERTIARY COMBINATIONS WITH Jatropha gossypifolia AND OTHER PLANT-DERIVED MOLLUSCICIDES ON REPRODUCTION AND SURVIVAL OF THE SNAIL Lymnaea acuminata

2014 ◽  
Vol 56 (5) ◽  
pp. 421-426 ◽  
Author(s):  
Ram P. Yadav ◽  
Ajay Singh
Keyword(s):  
Ellagic Acid ◽  
Active Component ◽  
Stem Bark ◽  
Freshwater Snail ◽  
Reproductive Capacity ◽  
Individual Leaf ◽  
Complex Process ◽  
Jatropha Gossypifolia ◽  
Lethal Doses ◽  
Lymnaea Acuminata

The effect of sub-lethal doses (40% and 80% of LC50/24h) of plant derived molluscicides of singly, binary (1:1) and tertiary (1:1:1) combinations of the Rutin, Ellagic acid, Betulin and taraxerol with J. gossypifolia latex, leaf and stem bark powder extracts and their active component on the reproduction of freshwater snail Lymnaea acuminata have been studied. It was observed that the J. gossypifolia latex, stem bark, individual leaf and their combinations with other plant derived active molluscicidal components caused a significant reduction in fecundity, hatchability and survival of young snails. It is believed that sub-lethal exposure of these molluscicides on snail reproduction is a complex process involving more than one factor in reducing the reproductive capacity.

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