Background:
Portage of therapeutic agents directly to the skin (cutaneous/dermal delivery) is the preferable approach in mitigating and curing a variety of skin manifestations, including
itching, eczema, acne, psoriasis keratinization, and skin cancer. Dermal delivery reduces side effects associated with systemic therapy and allows maximum utilization of the available doses. Invasomes are the next generation of liposomes with greater flexibility, elasticity, and permeability
through the skin than liposomes and ethosomes.
Objective:
This review article highlights various aspects of invasomes, including the structure and
composition of invasomes, methods of preparation of invasomes, the mechanism involved in better
penetration through the skin, key parameters to be considered for effective permeation, therapeutic
applications of invasomes as novel drug delivery systems, and future development and challenges.
Methods:
The authors have reviewed various primary and secondary sources, including PUBMED,
SCIENCE DIRECT, INFORMA, and patents.com, to collect information on various aspects of invasomes.
Results and Conclusion:
Invasomes are novel vesicular drug delivery systems that have been used
for dermal delivery of drugs for various therapeutic applications. These novel carriers have great
ability, and their properties can be highly modulated by varying their composition and concentration of terpenes. Based on all the research reports gathered, it is well proven that these systems
have a much higher potential for delivering drugs for skin manifestations and could expand the opportunities for treating various dermatological issues, increasing day by day.