The role of middle ear muscles in the development of resistance to noise induced hearing loss

1994 ◽  
Vol 74 (1-2) ◽  
pp. 22-28 ◽  
Author(s):  
Donald Henderson ◽  
Malini Subramaniam ◽  
Martin Papazian ◽  
Vlasta P. Spongr
Keyword(s):  
Hearing Loss ◽  
Middle Ear ◽  
Noise Induced Hearing Loss ◽  
Development Of Resistance

Protection from noise-induced hearing loss by prior exposure to a nontraumatic stimulus: Role of the middle ear muscles

1994 ◽  
Vol 72 (1-2) ◽  
pp. 23-28 ◽  
Author(s):  
Alien F. Ryan ◽  
Thecla M. Bennett ◽  
Nigel K. Woolf ◽  
Alf Axelsson
Keyword(s):  
Hearing Loss ◽  
Middle Ear ◽  
Prior Exposure ◽  
Noise Induced Hearing Loss

MicroRNAs in Noise-Induced Hearing Loss and their Regulation by Oxidative Stress and Inflammation

2020 ◽  
Vol 21 (12) ◽  
pp. 1216-1224
Author(s):  
Fatemeh Forouzanfar ◽  
Samira Asgharzade
Keyword(s):  
Oxidative Stress ◽  
Hearing Loss ◽  
Hair Cell ◽  
Noise Exposure ◽  
Cell Damage ◽  
Sensory Cells ◽  
Noise Induced Hearing Loss ◽  
Irreversible Damage ◽  
Open Access Journals

Noise exposure (NE) has been recognized as one of the causes of sensorineural hearing loss (SNHL), which can bring about irreversible damage to sensory hair cells in the cochlea, through the launch of oxidative stress pathways and inflammation. Accordingly, determining the molecular mechanism involved in regulating hair cell apoptosis via NE is essential to prevent hair cell damage. However, the role of microRNAs (miRNAs) in the degeneration of sensory cells of the cochlea during NE has not been so far uncovered. Thus, the main purpose of this study was to demonstrate the regulatory role of miRNAs in the oxidative stress pathway and inflammation induced by NE. In this respect, articles related to noise-induced hearing loss (NIHL), oxidative stress, inflammation, and miRNA from various databases of Directory of Open Access Journals (DOAJ), Google Scholar, PubMed; Library, Information Science & Technology Abstracts (LISTA), and Web of Science were searched and retrieved. The findings revealed that several studies had suggested that up-regulation of miR-1229-5p, miR-451a, 185-5p, 186 and down-regulation of miRNA-96/182/183 and miR-30b were involved in oxidative stress and inflammation which could be used as biomarkers for NIHL. There was also a close relationship between NIHL and miRNAs, but further research is required to prove a causal association between miRNA alterations and NE, and also to determine miRNAs as biomarkers indicating responses to NE.

The Role of Oxidative Stress in Noise-Induced Hearing Loss

2006 ◽  
Vol 27 (1) ◽  
pp. 1-19 ◽  
Author(s):  
Donald Henderson ◽  
Eric C. Bielefeld ◽  
Kelly Carney Harris ◽  
Bo Hua Hu
Keyword(s):  
Oxidative Stress ◽  
Hearing Loss ◽  
Noise Induced Hearing Loss

The role of glutathione in protection against noise-induced hearing loss*

1997 ◽  
Vol 117 (2) ◽  
pp. P94-P94
Author(s):  
T YAMASOBA ◽  
A NUTTALL ◽  
J MILLE
Keyword(s):  
Hearing Loss ◽  
Noise Induced Hearing Loss

Role of antioxidant supplementation in preventing noise induced hearing loss

2015 ◽  
Vol 13 (4) ◽  
pp. 160-165 ◽  
Author(s):  
Anna Rita Fetoni ◽  
Sara Letizia Maria Eramo ◽  
Fabiola Paciello ◽  
Rolando Rolesi ◽  
Diana Troiani ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Noise Induced Hearing Loss ◽  
Antioxidant Supplementation

scholarly journals Role of PGE-type receptor 4 in auditory function and noise-induced hearing loss in mice

2012 ◽  
Vol 62 (4) ◽  
pp. 1841-1847 ◽  
Author(s):  
Kiyomi Hamaguchi ◽  
Norio Yamamoto ◽  
Takayuki Nakagawa ◽  
Tomoyuki Furuyashiki ◽  
Shuh Narumiya ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Noise Induced Hearing Loss ◽  
Auditory Function ◽  
Type Receptor

scholarly journals The Role of MicroRNAs in Environmental Risk Factors, Noise-Induced Hearing Loss, and Mental Stress

2018 ◽  
Vol 28 (9) ◽  
pp. 773-796 ◽  
Author(s):  
Verónica Miguel ◽  
Julia Yue Cui ◽  
Lidia Daimiel ◽  
Cristina Espinosa-Díez ◽  
Carlos Fernández-Hernando ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hearing Loss ◽  
Environmental Risk ◽  
Mental Stress ◽  
Environmental Risk Factors ◽  
Noise Induced Hearing Loss

scholarly journals Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice

2016 ◽  
Vol 2016 ◽  
pp. 1-16 ◽  
Author(s):  
Xiaolong Fu ◽  
Linqing Zhang ◽  
Yecheng Jin ◽  
Xiaoyang Sun ◽  
Aizhen Zhang ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Outer Hair Cell ◽  
Cell Loss ◽  
Acoustic Trauma ◽  
Noise Induced Hearing Loss ◽  
Wild Type ◽  
Auditory Function ◽  
Susceptibility To Noise ◽  
Susceptible Gene

MYH14 is a member of the myosin family, which has been implicated in many motile processes such as ion-channel gating, organelle translocation, and the cytoskeleton rearrangement. Mutations in MYH14 lead to a DFNA4-type hearing impairment. Further evidence also shows that MYH14 is a candidate noise-induced hearing loss (NIHL) susceptible gene. However, the specific roles of MYH14 in auditory function and NIHL are not fully understood. In the present study, we used CRISPR/Cas9 technology to establish a Myh14 knockout mice line in CBA/CaJ background (now referred to as Myh14−/−mice) and clarify the role of MYH14 in the cochlea and NIHL. We found that Myh14−/−mice did not exhibit significant hearing loss until five months of age. In addition, Myh14−/−mice were more vulnerable to high intensity noise compared to control mice. More significant outer hair cell loss was observed in Myh14−/−mice than in wild type controls after acoustic trauma. Our findings suggest that Myh14 may play a beneficial role in the protection of the cochlea after acoustic overstimulation in CBA/CaJ mice.

scholarly journals Role of a Unique Innovative Device (HEAR-O-SCOPE) in Prevention of Noise Induced Hearing Loss

2021 ◽  
Vol 29 (1) ◽  
pp. 48-52
Author(s):  
Sreemanti Bag ◽  
Md. Quaisar Rahaman ◽  
Rajiv Singh ◽  
Chiranjib Das ◽  
Dwaipayan Mukherjee ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Electronic Device ◽  
Health Hazard ◽  
Noise Pollution ◽  
Peptic Ulcers ◽  
Noise Induced Hearing Loss ◽  
Long Run ◽  
Expected Benefits

Introduction Noise induced hearing loss has great significance in today’s world as it comes as an occupational health hazard accompanied with other systemic adverse effects like several neuropsychiatric disorders, cardiovascular diseases, or peptic ulcers. It can be prevented by serial follow up with pure tone audiograms and use of noise protectors like ear muffs or ear plugs. This article demonsrates an easy-to-adopt method of preventing noise induced hearing loss in the form of an electronic device named HEAR-O-SCOPE. Device Design This device is essentially a decibel meter which senses sound intensities above 85 decibel and equates it with permissible time of exposure for that decibel range and if permissible time of exposure is crossed, sends alarm signals in the form of buzzer and display, giving the user adequate time either to move away from the noisy surrounding or put in noise protectors. This device also has provision for real-time graphical plotting facilities. Expected Benefits Expected outcome by using this device in the long run would be early detection and prevention of noise induced hearing loss and other health hazards of noise pollution. Conclusion Regular use of HEAR-O-SCOPE is highly recommendable for prevention of Noise Induced Hearing Loss.

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