Event-related potentials and selective attention in healthy volunteers and schizophrenic patients with negative syndrome

1996 ◽  
Vol 18 (2-3) ◽  
pp. 231
Author(s):  
V. Eichert
Keyword(s):  
Selective Attention ◽  
Healthy Volunteers ◽  
Event Related Potentials ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Negative Syndrome

Auditory Selective Attention and Event-Related Potentials in Schizophrenia

1991 ◽  
Vol 158 (4) ◽  
pp. 534-539 ◽  
Author(s):  
Philip B. Ward ◽  
Stanley V. Catts ◽  
Allison M. Fox ◽  
Patricia T. Michie ◽  
Neil McConaghy
Keyword(s):  
Selective Attention ◽  
Event Related Potentials ◽  
Auditory Selective Attention ◽  
Attentional Deficits ◽  
Processing Negativity ◽  
Negative Thought ◽  
Long Duration ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Listening Task

Brain ERPs were recorded in ten unmedicated schizophrenic patients and age- and sex-matched healthy controls during a multidimensional listening task. Patients showed a marked reduction in a long-duration attention-related negative ERP component, termed ‘processing negativity’ (PN), which was elicited by attended stimuli. The amplitude of PN was significantly correlated with SANS and SAPS scores of schizophrenic symptoms. The P300 component was also reduced in amplitude in patients, and was significantly correlated with SANS ratings of negative thought disorder. These findings provide neurophysiological evidence of impairment in the maintenance of selective attention and the cognitive processes associated with target detection among schizophrenic patients. The reduced PN in schizophrenics implicates frontostriatal pathways in the aetiology of attentional deficits in schizophrenia.

An ERP Investigation of Semantic Priming, Repetition Priming, and Negative Priming in Schizophrenic Patients

2006 ◽  
Vol 20 (3) ◽  
pp. 195-211 ◽  
Author(s):  
Michael Wagner ◽  
Lioba Baving ◽  
Patrick Berg ◽  
Rudolf Cohen ◽  
Brigitte Rockstroh
Keyword(s):  
Negative Priming ◽  
Repetition Priming ◽  
Event Related Potentials ◽  
Decision Task ◽  
Positive Priming ◽  
Retrieval Processes ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Late Positive Complex ◽  
Automatic Memory

The processing of attended and nonattended stimuli in schizophrenic patients was examined with event-related potentials (ERPs) in a lexical decision task. In positive semantic and repetition priming the N400 amplitude did not differ between a group of 17 medicated schizophrenic patients and a group of 20 matched healthy controls. However, negative priming affected the N400 only in controls. Reaction time effects were dissociated from these ERP effects, with patients showing stronger positive priming than controls but identical negative priming. The semantic processes related to the N400 appear to be intact in schizophrenic patients, but patients seem to incorporate less context information (about the nonattended prime) in their episodic memory traces. A stronger increase of the posterior late positive complex in parallel to the stronger positive priming in schizophrenic patients may reflect relatively stronger automatic memory retrieval processes in patients.

Responses to External Emotions or their Transitions at Central to Peripheral Nervous System Levels: A Methodological Contribution to Mental Health

2020 ◽  
Vol 16 (2) ◽  
pp. 138-152
Author(s):  
Bingren Zhang ◽  
Chu Wang ◽  
Chanchan Shen ◽  
Wei Wang
Keyword(s):  
Healthy Volunteers ◽  
Psychiatric Patients ◽  
Event Related Potentials ◽  
Emotional Stimuli ◽  
Non Invasive ◽  
Related Potentials ◽  
Different Populations ◽  
Invasive Techniques ◽  
Psychiatric Problems ◽  
Different Levels

Background: Responses to external emotional-stimuli or their transitions might help to elucidate the scientific background and assist the clinical management of psychiatric problems, but pure emotional-materials and their utilization at different levels of neurophysiological processing are few. Objective: We aimed to describe the responses at central and peripheral levels in healthy volunteers and psychiatric patients when facing external emotions and their transitions. Methods: Using pictures and sounds with pure emotions of Disgust, Erotica, Fear, Happiness, Neutral, and Sadness or their transitions as stimuli, we have developed a series of non-invasive techniques, i.e., the event-related potentials, functional magnetic resonance imaging, excitatory and inhibitory brainstem reflexes, and polygraph, to assess different levels of neurophysiological responses in different populations. Results: Sample outcomes on various conditions were specific and distinguishable at cortical to peripheral levels in bipolar I and II disorder patients compared to healthy volunteers. Conclusions: Methodologically, designs with these pure emotions and their transitions are applicable, and results per se are specifically interpretable in patients with emotion-related problems.

Acute cholecystokinin effects on event-related potentials in healthy volunteers

2002 ◽  
Vol 17 (6) ◽  
pp. 285-291 ◽  
Author(s):  
Verner J. Knott ◽  
Colleen Mahoney ◽  
Tove Gunnarsson ◽  
Jacques Bradwejn ◽  
Jakov Shlik
Keyword(s):  
Healthy Volunteers ◽  
Event Related Potentials ◽  
Related Potentials

Event-related potentials in drug-naive schizophrenic patients

1991 ◽  
Vol 29 (3) ◽  
pp. 265-272 ◽  
Author(s):  
Marguirite Radwan ◽  
Haggai Hermesh ◽  
Matti Mintz ◽  
Hanan Munitz
Keyword(s):  
Event Related Potentials ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Drug Naïve

Event-Related Potentials During Memory Search and Selective Attention to Letter Size and Conjunctions of Letter Size and Color

1989 ◽  
Vol 26 (5) ◽  
pp. 529-547 ◽  
Author(s):  
Albertus A. Wijers ◽  
Gijsbertus Mulder ◽  
Tsunetaka Okita ◽  
Lambertus J.M. Mulder
Keyword(s):  
Selective Attention ◽  
Memory Search ◽  
Event Related Potentials ◽  
Related Potentials ◽  
Letter Size

Brain Indicators of Altered Attention and Information Processing in Schizophrenic Patients

1986 ◽  
Vol 148 (4) ◽  
pp. 414-420 ◽  
Author(s):  
K. Barrett ◽  
W. C. McCallum ◽  
P. V. Pocock
Keyword(s):  
Information Processing ◽  
Event Related Potentials ◽  
Normal Subjects ◽  
Detection Task ◽  
Auditory Target ◽  
Positive Potential ◽  
Stimulus Evaluation ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Target Detection Task

Late components of brain event-related potentials reflect aspects of selective attention, stimulus evaluation, and possibly memory update mechanisms. Several of these components were measured during an auditory target detection task, performed by 20 schizophrenic and 20 normal subjects. Both the amplitude of those components and a more general late amplitude measure were significantly reduced in schizophrenics, for both target and non-target stimuli. One general late amplitude measure, from the scalp vertex, could alone correctly classify 85% of patients and 95% of controls. The source of these differences may lie in a protracted positive potential shift.

scholarly journals Symmetrical electrophysiological brain responses to unilateral and bilateral auditory stimuli suggest disrupted spatial processing in schizophrenia

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Sara Sardari ◽  
Ali Mohammad Pourrahimi ◽  
Hossein Talebi ◽  
Shahrzad Mazhari
Keyword(s):  
Mismatch Negativity ◽  
Event Related Potentials ◽  
Frequency Discrimination ◽  
Stimulus Location ◽  
Spatial Processing ◽  
Healthy Individuals ◽  
Brain Responses ◽  
Schizophrenic Patients ◽  
Related Potentials ◽  
Processing Deficits

Abstract Research has found auditory spatial processing deficits in patients with schizophrenia (SCZ), but no study has examined SCZ patients’ auditory spatial processing at both pre-attentional and attentional stages. To address this gap, we investigated schizophrenics’ brain responses to sounds originating from different locations (right, left, and bilateral sources). The event-related potentials (ERPs) of 25 chronic schizophrenic patients and 25 healthy subjects were compared. Mismatch negativity (MMN) in response to frequency and duration deviants was assessed. Two P3 components (P3a and P3b) were elicited via a frequency discrimination task, and MMN and P3 were recorded through separate monaural and dichotic stimulation paradigms. Our results corroborated the previously published finding that MMN, P3a, and P3b amplitudes are reduced in SCZ patients, but they showed no significant effect of stimulus location on either MMN or P3. These results indicated similarity between the SCZ patients and healthy individuals as regards patterns of ERP responses to stimuli that come from different directions. No evidence of auditory hemispatial bias in the SCZ patients was found, supporting the existence of non-lateralized spatial processing deficits in such patients and suggesting compensatory changes in the hemispheric laterality of patients’ brains.

Sign in / Sign up

Export Citation Format

Share Document