Long term effect of treatment by tamoxifen in women treated for breast cancer. A retrospective study and comparaison with control subjects

1993 ◽  
Vol 29 ◽  
pp. S75
Author(s):  
L Cals ◽  
D Vallicioni ◽  
D Clairet ◽  
J Eisinger
Keyword(s):  
Breast Cancer ◽  
Retrospective Study ◽  
Term Effect ◽  
Control Subjects ◽  
Long Term Effect ◽  
Effect Of Treatment

scholarly journals Windows in early mammary development: critical or not?

Reproduction ◽  
2001 ◽  
pp. 337-345 ◽  
Author(s):  
CH Knight ◽  
A Sorensen
Keyword(s):  
Breast Cancer ◽  
Milk Yield ◽  
Proliferative Activity ◽  
Mammary Development ◽  
Term Effect ◽  
Critical Window ◽  
Dairy Heifers ◽  
Long Term Effect ◽  
Long Term Consequences

Two critical windows in mammary development have been proposed. The first arises from observations in rodents that nutrition during fetal and neonatal periods can affect mammary ductular outgrowth, subsequent proliferative activity and, eventually, tumorigenesis, that is, potentially it could have a long-term effect on pathological outcome (breast cancer) in women. The second similarly involves early diet, but in this case the outcome is phenotypic, in that dairy heifers reared too quickly during the peripubertal period subsequently show impaired udder development and reduced milk yield persisting throughout life. Most mammary development occurs during pregnancy, but this period is usually thought of only in terms of the immediate outcome for the subsequent lactation; it is not believed to be a critical window, at least in terms of lifetime mammary productivity. This review examines the evidence underlying these various claims and attempts to define the mechanisms involved, and also considers whether derangements occurring earlier in life (prenatally) could also have long-term consequences for physiological or pathological mammary development.

scholarly journals Short and long term effect of treatment non-pharmacological and lifestyle in patients with metabolic syndrome

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Ana Denise Brandão ◽  
Jeferson Hernandes da Silva ◽  
Sarah Mariane Oliveira Lima ◽  
Leiciane Lima ◽  
Bhianca Loize ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Term Effect ◽  
Long Term Effect ◽  
Short And Long Term ◽  
Effect Of Treatment

Long-term effect of exercise on depression after breast cancer treatment

2010 ◽  
Author(s):  
Brian Gonzalez ◽  
Yasmin Asvat ◽  
Michael Andrykowski ◽  
Paul Jacobsen
Keyword(s):  
Breast Cancer ◽  
Cancer Treatment ◽  
Breast Cancer Treatment ◽  
Term Effect ◽  
Long Term Effect

Long-term Effect of Inhaled Corticosteroids on Growth Rate in Adolescents With Asthma

PEDIATRICS ◽  
1993 ◽  
Vol 91 (6) ◽  
pp. 1121-1126 ◽  
Author(s):  
Peter J.F.M. Merkus ◽  
Philip H. Quanjer ◽  
Elisabeth E.M. van Essen-Zandvliet ◽  
Karel F. Kerrebijn ◽  
Eric J. Duiverman ◽  
...  
Keyword(s):  
Growth Rates ◽  
Inhaled Corticosteroids ◽  
Term Effect ◽  
Controlled Study ◽  
Double Blind ◽  
Control Subjects ◽  
Long Term Effect ◽  
Median Period ◽  
Healthy Control

Background. Growth in stature in asthmatic adolescents may be delayed compared to normals as a result of treatment with inhaled corticosteroids (CS) or because of a delay in puberty. However, growth rates in asthmatic children have never been studied when treatment with CS was randomized and when growth was compared with that of matched healthy control subjects. Objective. To assess the long-term effect of CS treatment on growth rates in asthmatic adolescents. Methods. Participants were 40 asthmatic teenagers (mean age 12.8 years) who received randomized treatment with 0.2 mg of albuterol (salbutamol) with either placebo three times a day (BA + PL) or 0.2 mg of budesonide three times a day (BA + CS) for a median period of 22 months in a double-blind controlled study. Growth rates were compared with those of 80 control subjects who were matched for sex, age, height, and duration of follow-up. Results. Growth rates in male patients, but not in female patients, were significantly less than in control subjects (P < .05), a finding consistent with a delay of puberty due to asthma. The mean difference (95% confidence interval) in growth rates between patients treated with BA + PL and their controls was -0.70 (–1.62, 0.22) cm/y; that between patients treated with BA + CS and their controls was -0.44 (–1.25, 0.37) cm/y. The observed mean (SEM) case-control difference between treatment groups was + 0.27 (0.58) cm/y in favor of BA + CS. Conclusion. Growth retardation observed in adolescents with asthma may be due to a delay in puberty but not to the prescription of 0.6 mg of budesonide daily.

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