Bone mineral density in asthmatic women on high-dose inhaled beclomethasone dipropionate

Bone ◽  
1994 ◽  
Vol 15 (6) ◽  
pp. 621-623 ◽  
Author(s):  
J. Herrala ◽  
H. Puolijoki ◽  
O. Impivaara ◽  
K. Liippo ◽  
E. Tala ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Beclomethasone Dipropionate ◽  
High Dose ◽  
Mineral Density

Change in bone mineral density with high-dose prednisone in patients with rheumatoid arthritis

2016 ◽  
Author(s):  
Linda Rasch ◽  
Tuyl Lilian van ◽  
Martijn Kremer ◽  
Irene Bultink ◽  
Maarten Boers ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
High Dose ◽  
Mineral Density ◽  
Dose Prednisone

scholarly journals Lack of Association between Pulse Steroid Therapy and Bone Mineral Density in Patients with Multiple Sclerosis

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Serap Zengin Karahan ◽  
Cavit Boz ◽  
Sevgi Kilic ◽  
Nuray Can Usta ◽  
Mehmet Ozmenoglu ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Femoral Neck ◽  
Bone Mineral ◽  
Steroid Therapy ◽  
Negative Relationship ◽  
High Dose ◽  
Mineral Density ◽  
Factors Affecting

Multiple sclerosis (MS) has been associated with reduced bone mineral density (BMD). The purpose of this study was to determine the possible factors affecting BMD in patients with MS. We included consecutive 155 patients with MS and 90 age- and sex-matched control subjects. Patients with MS exhibited significantly lowerT-scores andZ-scores in the femoral neck and trochanter compared to the controls. Ninety-four (61%) patients had reduced bone mass in either the lumbar spine or the femoral neck; of these, 64 (41.3%) had osteopenia and 30 (19.4%) had osteoporosis. The main factors affecting BMD were disability, duration of MS, and smoking. There was a negative relationship between femoral BMD and EDSS and disease duration. No association with lumbar BMD was determined. There were no correlations between BMD at any anatomic region and cumulative corticosteroid dose. BMD is significantly lower in patients with MS than in healthy controls. Reduced BMD in MS is mainly associated with disability and duration of the disease. Short courses of high dose steroid therapy did not result in an obvious negative impact on BMD in the lumbar spine and femoral neck in patients with MS.

Bone mineral density of the left femoral neck in lymphoma survivors treated with high dose therapy with autologous stem cell support.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e20612-e20612
Author(s):  
Mette Seland ◽  
Knut Halvor B Smeland ◽  
Harald Holte ◽  
Trine Bjoero ◽  
Kristin Godang ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Stem Cell ◽  
Femoral Neck ◽  
Bone Mineral ◽  
High Dose ◽  
Mineral Density ◽  
High Dose Therapy ◽  
Stem Cell Support ◽  
Lymphoma Survivors ◽  
Cell Support

scholarly journals Vitamin-D status and bone mineral density in asthmatic children on long-term inhaled corticosteroids

2020 ◽  
Vol 35 ◽  
pp. 39-47
Author(s):  
B. Thanuja ◽  
M. R. Savitha
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Mineral ◽  
Inhaled Corticosteroids ◽  
High Dose ◽  
Mineral Density ◽  
Chronic Therapy ◽  
Vitamin D Levels ◽  
The Impact

Asthma is the most common chronic respiratory illness affecting children. Inhaled corticosteroids (ICS) form the main treatment modality in asthma. Reduction in bone mineral density (BMD) is an important adverse effect of steroid usage. This side effect is an established entity with oral corticosteroids but minimal with ICS therapy. However, there are reports regarding the detrimental effect of chronic therapy with ICS. Long-term high-dose budesonide more than 800 μg/day has been shown to reduce the BMD. However, this effect was not consistently seen with moderate doses of 400–800 μg/day. Anticipating the impact of steroids on bone metabolism and monitoring for it is essential. Annual monitoring of Vitamin-D levels and BMD in children on chronic therapy is beneficial for the early detection and management of steroid-induced osteopenia. Judicious ICS use at the lowest effective dose should be tailor-made for every individual.

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