Engineering 2D and 3D Cellular Microenvironments Using Laser Direct Write

2015 ◽  
pp. 105-127 ◽  
Author(s):  
Andrew D. Dias ◽  
David M. Kingsley ◽  
David T. Corr
Keyword(s):  
Direct Write ◽  
Cellular Microenvironments ◽  
2D And 3D ◽  
Laser Direct Write

scholarly journals Directed Self-Assembly Software for Single Cell Deposition

2017 ◽  
Vol 3 (2) ◽  
Author(s):  
Samuel C Sklare ◽  
Winona Richey ◽  
Benjamin T Vinson ◽  
Doug B Chrisey
Keyword(s):  
Self Assembly ◽  
Scale Up ◽  
Sensor Data ◽  
Direct Write ◽  
Control Software ◽  
Integrated Sensor ◽  
Experimental Conditions ◽  
Cad Cam ◽  
Cellular Microenvironments ◽  
Laser Direct Write

Laser direct-write (LDW) bioprinting methods offer a diverse set of tools to design experiments, fabricate tissue constructs and cellular microenvironments all in a CAD/CAM matter. To date, we have just scratched the surface of the system’s potential. For LDW to be utilized to its maximum there are many distinct hardware and software components that must integrate and communicate seamlessly. In this perspective articles, we detail the development of novel graphical user interface (GUI) software to improve laser direct-write capability and functionality. The main modules in the control software correspond to cell transfer, microbead fabrication, and micromachining. Modules make the control of each of these features and the management of printing programs that utilize one or more features facile. The software also addresses problems related to construct scale-up, print speed, experimental conditions, and management of sensor data. The control software and possibilities for integrated sensor data are presented.

Redistribution of pads on a singulated IC die using laser direct-write ablation

2006 ◽  
Vol 29 (1) ◽  
pp. 184-189
Author(s):  
Chengping Zhang ◽  
R. Bartholomew ◽  
P.C. Karulkar
Keyword(s):  
Direct Write ◽  
Laser Direct Write

Picoliter-Scale Protein Microarrays by Laser Direct Write

2002 ◽  
Vol 18 (5) ◽  
pp. 1126-1129 ◽  
Author(s):  
B.R. Ringeisen ◽  
P.K. Wu ◽  
H. Kim ◽  
A. Pique ◽  
R.Y.C. Auyeung ◽  
...  
Keyword(s):  
Protein Microarrays ◽  
Direct Write ◽  
Laser Direct Write

scholarly journals Nanofabrication on 2D and 3D Topography via Positive‐Tone Direct‐Write Laser Lithography

2019 ◽  
Vol 22 (2) ◽  
pp. 1901290
Author(s):  
Samuli Heiskanen ◽  
Zhuoran Geng ◽  
Jaakko Mastomäki ◽  
Ilari J. Maasilta
Keyword(s):  
Direct Write ◽  
Laser Lithography ◽  
3D Topography ◽  
2D And 3D

Rapid prototyping of micropower sources by laser direct-write

2004 ◽  
Vol 79 (4-6) ◽  
pp. 783-786 ◽  
Author(s):  
A. Piqué ◽  
C.B. Arnold ◽  
H. Kim ◽  
M. Ollinger ◽  
T.E. Sutto
Keyword(s):  
Rapid Prototyping ◽  
Direct Write ◽  
Laser Direct Write

Fabrication of Hybrid Cell-Microbead Constructs Using Laser Direct-Write of Alginate Microbeads and Adherent Breast Cancer Cells

2013 ◽  
Author(s):  
Andrew D. Dias ◽  
David M. Kingsley ◽  
Douglas B. Chrisey ◽  
David T. Corr
Keyword(s):  
Drug Delivery ◽  
Mammalian Cells ◽  
Hybrid Cell ◽  
High Surface ◽  
High Surface Area ◽  
Volume Ratio ◽  
Direct Write ◽  
Cellular Interactions ◽  
Paracrine Signaling ◽  
Laser Direct Write

Microbeads are becoming popular tools in tissue engineering as 3D microstructure hydrogels. The gel nature of microbeads enables them to sequester soluble factors and mammalian cells, and their high surface area-to-volume ratio allows diffusion between the bead and the environment [1,2]. Microbeads are thus good systems for drug delivery and can serve as 3D microenvironments for cells. To fully maximize their potential as delivery systems and microenvironments, it is highly desirable to create spatially-precise hybrid cultures of microbeads and mammalian cells. Precise placement of microbeads in proximity to patterned cells will allow the study of spatial cellular interactions, paracrine signaling, and drug delivery.

Ultrafast Laser Processing for Lab-on-a-Chip Device Manufacture

2004 ◽  
Vol 850 ◽  
Author(s):  
Koji Sugioka ◽  
Ya Cheng ◽  
Katsumi Midorikawa
Keyword(s):  
Heat Treatment ◽  
Laser Processing ◽  
Lab On A Chip ◽  
Ultrafast Laser ◽  
Wet Etching ◽  
Direct Write ◽  
Electric Control ◽  
Fs Laser ◽  
Laser Direct Write ◽  
Hollow Microstructures

ABSTRACT3D microstructuring of photosensitive glass is demonstrated by femtosecond (fs) laser for lab-on-a-chip manufacture. True 3D hollow microstructures embedded in the glass are fabricated by the fs laser direct write followed by heat treatment and successive wet etching. A variety of microcomponents for a lab-on-a-chip device like a microfluidics, a microvalve, a microoptics, a microlaser, etc. are fabricated by using this technique. The fs laser direct write process is also applied for selective metallization of internal walls of the hollow microstructures embedded in the glass for electric control of movement of the micromechanical components in the lab-on-a-chip device.

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