ATRX tames repetitive DNA within heterochromatin to promote normal brain development and regulate oncogenesis

2019 ◽  
pp. 235-257
Author(s):  
Valerie Turcotte-Cardin ◽  
Kevin G. Young ◽  
David J. Picketts
Keyword(s):  
Brain Development ◽  
Repetitive Dna ◽  
Normal Brain ◽  
Normal Brain Development

scholarly journals The diffusion tensor imaging (DTI) component of the NIH MRI study of normal brain development (PedsDTI)

NeuroImage ◽  
2016 ◽  
Vol 124 ◽  
pp. 1125-1130 ◽  
Author(s):  
Lindsay Walker ◽  
Lin-Ching Chang ◽  
Amritha Nayak ◽  
M. Okan Irfanoglu ◽  
Kelly N. Botteron ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Brain Development ◽  
Diffusion Tensor ◽  
Normal Brain ◽  
Mri Study ◽  
Normal Brain Development ◽  
Diffusion Tensor Imaging Dti

scholarly journals Coxsackievirus B3 infection affects neurogenesis and hinders normal brain development

2008 ◽  
Vol 2 (Suppl 1) ◽  
pp. P61
Author(s):  
Chelsea M Ruller ◽  
Jenna M Tabor-Godwin ◽  
Scott Robinson ◽  
Naili An ◽  
J Lindsay Whitton ◽  
...  
Keyword(s):  
Brain Development ◽  
Coxsackievirus B3 ◽  
Normal Brain ◽  
Normal Brain Development

scholarly journals Dynamic N6-methyladenosine RNA methylation in brain and diseases

Epigenomics ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 371-380 ◽  
Author(s):  
Andrew M Shafik ◽  
Emily G Allen ◽  
Peng Jin
Keyword(s):  
Brain Development ◽  
Rna Modification ◽  
Normal Brain ◽  
Biological Processes ◽  
Future Directions ◽  
Body Of Knowledge ◽  
Neuropsychiatric Diseases ◽  
The Brain ◽  
Normal Brain Development

N6-methyladenosine (m6A) is a dynamic RNA modification that regulates various aspects of RNA metabolism and has been implicated in many biological processes and transitions. m6A is highly abundant in the brain; however, only recently has the role of m6A in brain development been a focus. The machinery that controls m6A is critically important for proper neurodevelopment, and the precise mechanisms by which m6A regulates these processes are starting to emerge. However, the role of m6A in neurodegenerative and neuropsychiatric diseases still requires much elucidation. This review discusses and summarizes the current body of knowledge surrounding the function of the m6A modification in regulating normal brain development, neurodegenerative diseases and outlines possible future directions.

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