Westernization and today’s changing life style is resulting in various health problems like
Inflammatory Bowel diseases, which is a common entity encountered in surgical practise. Ulcerative
colitis is the most common among them. Though it is believed to have auto immune and genetic
origin, today’s life style, environment, diet and stress plays an important role in aetiology. The disease
is prevalent in middle aged western and northern people characterised by abdominal pain with bloody
diarrhoea, weight loss, anaemia and general debility. This condition has remissions and exacerbations.
One should always keep in mind that inflammatory bowel diseases can have anorectal manifestations.
Diagnosis is made on the basis of symptoms, stool exam. and endoscopy. Management is
symptomatic i.e. antibiotics, anti-inflammatory, anti-spasmodic, multivitamins, immune suppression
and if required admission, intravenous fluids. if no response colectomy. As such there is no
satisfactory treatment till date, so it remains the difficult issue. Here we need to have an alternative,
safe, convenient treatment. Ayurveda has an answer for such cases.
CD13hi Neutrophil-like myeloid-derived suppressor cells exert immune suppression through Arginase 1 expression in pancreatic ductal adenocarcinoma