Nanoimprint lithography and transdermal drug-delivery devices

Author(s):  
Rizgar Jiawook ◽  
Babak Heidari
2019 ◽  
Vol 565 ◽  
pp. 41-49 ◽  
Author(s):  
Tomomi Hatanaka ◽  
Takanori Saito ◽  
Takaaki Fukushima ◽  
Hiroaki Todo ◽  
Kenji Sugibayashi ◽  
...  

2013 ◽  
Vol 25 (4) ◽  
pp. 949-960
Author(s):  
M. Garshasbi ◽  
H. Kamal Gharibi ◽  
P. Reihani Ardabili

1989 ◽  
Vol 7 (3) ◽  
pp. 25-31 ◽  
Author(s):  
Philip W. Ledger ◽  
Kirstin C. Nichols

2021 ◽  
Vol 72 (1) ◽  
pp. 90-99
Author(s):  
Narcis Anghel ◽  
Maria Valentina Dinu ◽  
Florica Doroftei ◽  
Iuliana Spiridon

Here we present a new drug delivery system based on xanthan esterified with acrylic acid. This material served as a matrix for the incorporation of bioactive substances with antimicrobial and anti-inflammatory properties. The materials were characterized by Fourier Transform Infrared Spectroscopy (FTIR), Nuclear Magnetic Resonance (NMR) and Scanning Electron Micrography (SEM). Mechanical strength tests showed a substantial improvement in the resilience and flexibility of the polymer matrix modified by esterification under conditions of mechanical stress. The release of bioactive substances from the basic matrix follows a Korsmeyer-Peppas type kinetics. The modified xanthan-based transport system was shown to be antimicrobially active with an inhibition rate of almost 100% on gram-positive and gram-negative bacteria. The obtained results recommend this biomaterial for the manufacture of transdermal drug delivery devices.


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