Bone Marrow Aspiration and Core Biopsy

2013 ◽  
pp. 552-553
Keyword(s):  
Bone Marrow ◽  
Core Biopsy ◽  
Bone Marrow Aspiration

Comparison of a Rotary Powered Bone Marrow Aspiration and Biopsy Device to the Traditional Manual Device in an Adolescent

Blood ◽  
2012 ◽  
Vol 120 (21) ◽  
pp. 4718-4718 ◽  
Author(s):  
Maria G. Falcon ◽  
Chatchawin Assanasen ◽  
Paul Thomas ◽  
Victor Saldivar
Keyword(s):  
Bone Marrow ◽  
Pain Score ◽  
Core Biopsy ◽  
Research Funding ◽  
Iliac Crest ◽  
Bone Marrow Aspiration ◽  
Bone Marrow Examination ◽  
Procedural Pain ◽  
Bone Marrow Biopsies ◽  
Biopsy Device

Abstract Abstract 4718 Bone marrow examination is important for the diagnosis of hematological malignancies and nonmalignant diseases in children. In patients with newly diagnosed lymphoproliferative diseases and certain non-hematopoietic malignancies, bone marrow examination is also part of the staging process. Core biopsy length has been found to be critical in diagnosing, predicting relapse or identifying residual disease following chemotherapy in patients. The larger the amount of marrow obtained increases the chance of finding a focal lesion. Unfortunately, the current practice of obtaining trephine biopsies and bone marrow aspirates in children via the manual method has a poor success rate for obtaining adequate specimens. In 2007, an FDA-cleared battery powered bone marrow aspiration and biopsy system (OnControl™ by Vidacare) was developed. Multiple studies have evaluated the use of the powered device in adults and found decreased time of procedure, decreased pain, and improved core biopsy specimens. Here we present a direct comparison of the rotary powered device versus the traditional manual device (e.g. Jamshidi) when obtaining bilateral bone marrow aspirates and biopsies in a 17 year-old female with relapsed alveolar rhabdomyosarcoma. This patient required bilateral bone marrow biopsies to stage her disease and evaluate for bone marrow involvement. One aspirate and biopsy was obtained using the powered device from the right posterior superior iliac crest, and specimens were obtained from the left iliac crest using the traditional manual device. The endpoints measured were quality of the biopsy, length and width of the biopsy, time to obtain aspirate and biopsy, number of attempts to obtain the biopsy, post-procedural pain, and operator satisfaction with the device (O.S.). Device Quality Rating Length (mm) Width (mm) Aspirate Time (sec) Biopsy Time (sec) Attempts Pain Score (0–10) O.S. (0–10) Powered 2 9 1.5 20 108 1 0 10 Manual 1 14 2 25 225 1 0 9 In conclusion, the powered device was superior to the manual device in terms of time to obtain the aspirate and biopsy and operator satisfaction with the device. It was found to be equivalent to the manual device in regards to number of attempts to obtain the biopsy, and post-procedural pain score. The manual device produced a biopsy that was longer, wider, and of higher quality than the biopsy obtained via the powered method. A randomized controlled trial in the pediatric population comparing the rotary powered device to the traditional device is currently underway as further studies are needed to evaluate the use of the powered bone marrow aspiration and biopsy device in children. Disclosures: Falcon: Vidacare Corporation: Research Funding. Assanasen:Vidacare Corporation: Research Funding.

Bone marrow solid core biopsy needle: a critical assessment of the utility, benefits and limitations of the instruments employed in current day haematology and oncology

2017 ◽  
Vol 71 (6) ◽  
pp. 475-482 ◽  
Author(s):  
Anwarul Islam
Keyword(s):  
Bone Marrow ◽  
Core Biopsy ◽  
Bone Marrow Aspiration ◽  
Histological Evaluation ◽  
Solid Core ◽  
Biopsy Needle ◽  
Morphological Evaluation ◽  
Biopsy Specimens ◽  
Single Use ◽  
User Friendly

The optimal clinical evaluation of the bone marrow requires an examination of air-dried and well-stained films of the aspirated tissue along with a histopathological evaluation of adequately processed and properly stained core biopsy specimens. A bone marrow evaluation can be essential in establishing a diagnosis, determining the efficacy of treatment in haematological disorders and to monitor haematological status of patients following bone marrow/stem cell transplantation. It is also an essential component of the staging process for newly diagnosed malignancies. Currently available bone marrow aspiration needles are quite satisfactory and if properly used provide good-quality specimens for morphological evaluation. However, if a bone marrow core biopsy is concerned, several needles are currently in use but not all of them provide good-quality biopsy specimens for histological evaluation or are user friendly. We have compared the recently introduced Moeller Medical single use bone marrow core biopsy needle with the Jamshidi needle with marrow acquisition cradle (CareFusion), J-needle (Cardinal Health) and OnControl device (Vidacare). It is concluded that the Moeller Medical needle system has definite advantages over others and is recommended for routine use.

scholarly journals Bone Marrow Clot Section a Useful Tool for Diagnosis of Haematological Diseases- A Case Series

2021 ◽  
Author(s):  
Parul Garg ◽  
Harjot Kaur ◽  
Ishwer Tayal ◽  
Aradhana Singh Hada
Keyword(s):  
Bone Marrow ◽  
Diagnostic Tool ◽  
Core Biopsy ◽  
Case Series ◽  
Bone Marrow Aspiration ◽  
Bone Marrow Examination ◽  
Biopsy Material ◽  
Haematological Disorders ◽  
Neoplastic Disorders

Bone marrow examination is required for diagnosis of various haematological disorders. It includes both neoplastic and non-neoplastic disorders. Usually, bone marrow examination includes Bone Marrow Aspiration (BMA), bone marrow biopsy and bone marrow imprints. Bone marrow clot sections can also be an adjuvant of bone marrow examination. The bone marrow clot sections are prepared from the left-over blood after aspirate smears have been prepared. An adequate bone marrow clot section can be valuable for diagnosis of various diseases, especially in cases in which the aspirate and core biopsy material are inadequate or non contributory or it can be an adjuvant procedure. Little has been published about usefulness of bone marrow clot section. Studies are going on to evaluate the role of bone marrow clot section as an adjuvant or a diagnostic tool. This study includes a series of three cases in which bone marrow clot section was diagnostic.

scholarly journals CT Guided Bone Marrow Aspiration and Core Biopsy

2012 ◽  
Vol 02 (02) ◽  
pp. 55-56 ◽  
Author(s):  
Carlos M. Badiola ◽  
Folco Scappaticci ◽  
Driola Brahaj
Keyword(s):  
Bone Marrow ◽  
Core Biopsy ◽  
Bone Marrow Aspiration ◽  
Ct Guided

Vitamin B12 Deficiency an Unusual Cause of Fever: A Case Report

2019 ◽  
Vol 4 (02) ◽  
Author(s):  
Shyama . ◽  
P. Kumar ◽  
Surabhi .
Keyword(s):  
Bone Marrow ◽  
Vitamin B12 ◽  
Unusual Case ◽  
Vitamin B12 Deficiency ◽  
Bone Marrow Aspiration ◽  
Microcytic Anemia ◽  
Peripheral Smear ◽  
Erythroid Hyperplasia ◽  
B12 Deficiency ◽  
Vitamin B12 Supplementation

Introduction: An unusual case of a 19 year old female, presenting with fever, pallor and hepatosplenomegaly for one month. She had microcytic anemia on peripheral smear examination but her bone marrow aspiration & biopsy revealed a hypercelluar marrow with megaloblastic erythroid hyperplasia. Resolution of fever within 48 hours of Vitamin B12 supplementation, initiated in view of the megaloblastic bone marrow picture & low serumVitamin B12 level, suggests a causal association. Conclusion: Vitamin B12 deficiency seems to be an unusual cause of PUO (Pyrexia of unkown origin) which should be ruled out in every case of PUO.

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