Detection of prion protein immune complex for bovine spongiform encephalopathy diagnosis using fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy

2007 ◽  
Vol 370 (2) ◽  
pp. 131-141 ◽  
Author(s):  
Fumihiko Fujii ◽  
Motohiro Horiuchi ◽  
Masayoshi Ueno ◽  
Hiroshi Sakata ◽  
Issei Nagao ◽  
...  
Keyword(s):  
Bovine Spongiform Encephalopathy ◽  
Prion Protein ◽  
Immune Complex ◽  
Fluorescence Correlation Spectroscopy ◽  
Cross Correlation ◽  
Correlation Spectroscopy ◽  
Spongiform Encephalopathy ◽  
Fluorescence Correlation

scholarly journals Interferometric Fluorescent Cross Correlation Spectroscopy

2019 ◽  
Author(s):  
Ipsita Saha ◽  
Saveez Saffarian
Keyword(s):  
Quantum Dots ◽  
Fluorescence Correlation Spectroscopy ◽  
Cross Correlation ◽  
Single Photon ◽  
Theoretical Framework ◽  
Correlation Spectroscopy ◽  
Aqueous Samples ◽  
Cellular Membranes ◽  
Fluorescence Correlation ◽  
Fluorescent Molecules

AbstractWe present a method utilizing single photon interference and fluorescence correlation spectroscopy (FCS) to simultaneously measure transport of fluorescent molecules within aqueous samples. Our method, within seconds, measures transport in thousands of homogenous voxels (100 nm)3 and eliminates photo-physical artifacts associated with blinking of fluorescent molecules. A comprehensive theoretical framework is presented and validated by measuring transport of quantum dots, associated with VSV-G receptor along cellular membranes as well as within viscous gels.

Sign in / Sign up

Export Citation Format

Share Document