Ultrasensitive and easily reproducible biosensor based on novel doped MoS2 nanowires field-effect transistor in label-free approach for detection of hepatitis B virus in blood serum

2021 ◽  
Vol 1156 ◽  
pp. 338360
Author(s):  
Mohsen Shariati ◽  
Maryam Vaezjalali ◽  
Mahdi Sadeghi
2014 ◽  
Vol 34 (3) ◽  
pp. 273-277 ◽  
Author(s):  
Chia-Yu Wu ◽  
Han-Yi Cheng ◽  
Keng-Liang Ou ◽  
Chi-Chang Wu

Abstract Devices based on semiconducting nanowires (NWs) are functioning as highly sensitive and selective sensors for the label-free detection of biological and chemical species. This paper demonstrates a novel back-gated silicon NW field effect transistor (NWFET) for gene detection. The fabricated NWFET was employed as the biomolecule sensor for the early, real-time, and label-free screening of hepatitis B virus (HBV) X gene. The DNA fragment in HBV demonstrates the linearity from 10 fM to 1 pM, of which the detection limit is estimated to be about 3.2 fM. The obtained results also show that the NW-based sensor can distinguish the difference between the complementary and 1-base mismatch DNA. The back-gated NW FET exhibits a label-free, highly sensitive, and selective biosensor for gene detection, which also provides a possibility of multiple chemical and biological species detection with sensor array in an integrated chip.


2D Materials ◽  
2021 ◽  
Author(s):  
Mohammad Mosarof Hossain ◽  
Babar Shabbir ◽  
Yingjie Wu ◽  
Wenzhi Yu ◽  
Vaishnavi Krishnamurthi ◽  
...  

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