Stealth properties of poly(ethylene oxide)-based triblock copolymer micelles: A prerequisite for a pH-triggered targeting system

2011 ◽  
Vol 7 (10) ◽  
pp. 3700-3707 ◽  
Author(s):  
K. Van Butsele ◽  
M. Morille ◽  
C. Passirani ◽  
P. Legras ◽  
J.P. Benoit ◽  
...  
RSC Advances ◽  
2015 ◽  
Vol 5 (64) ◽  
pp. 52105-52120 ◽  
Author(s):  
E. Villar-Alvarez ◽  
E. Figueroa-Ochoa ◽  
S. Barbosa ◽  
J. F. A. Soltero ◽  
P. Taboada ◽  
...  

Reverse triblock copolymer micelles with lengthy polyethylene oxide blocks as efficient sustained dual drug-loaded nanocarriers.


Biomaterials ◽  
2004 ◽  
Vol 25 (17) ◽  
pp. 3553-3558 ◽  
Author(s):  
Mingxiao Deng ◽  
Rong Wang ◽  
Guangzhuo Rong ◽  
Jingru Sun ◽  
Xuefei Zhang ◽  
...  

2019 ◽  
Vol 72 (2) ◽  
pp. 155
Author(s):  
Aya Saruwatari ◽  
Kei Hashimoto ◽  
Ryota Tamate ◽  
Ryoji Usui ◽  
Hisashi Kokubo ◽  
...  

We report the photocontrollable micelle–cluster transition of an ABC-type triblock copolymer in an ionic liquid (IL). Polystyrene-b-poly(ethylene oxide)-b-poly(4-phenylazobenzyl acrylamide-r-N-isopropylacrylamide) (PSt-b-PEO-b-P(AzoBnAm-r-NIPAm)) was synthesised, where PSt is IL-phobic, PEO is IL-philic, and P(AzoBnAm-r-NIPAm) is photo- and thermoresponsive in the IL. At high temperatures, the triblock copolymer forms micelles with PSt cores; furthermore, at low temperatures, micelles self-assemble into clusters induced by the aggregation of P(AzoBnAm-r-NIPAm). Under UV irradiation, the micelles form clusters at lower temperatures than that in the dark because of the change in the solubility of P(AzoBnAm-r-NIPAm) induced by photoisomerisation of the azobenzene groups, indicating that this triblock copolymer has a photocontrollable micelle–cluster transition temperature.


1993 ◽  
Vol 26 (8) ◽  
pp. 1825-1828 ◽  
Author(s):  
Zdenek Hruska ◽  
Mark Piton ◽  
Ahmad Yekta ◽  
Jean Duhamel ◽  
Mitchell A. Winnik ◽  
...  

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